Results 71 to 80 of about 79,292,901 (294)

Vitamin B 12 Deficiency and Multiple Sclerosis; Is there Any Association?

International Journal of Preventive Medicine, 2012
Background: Vitamin B 12 (Cobalamin) deficiency can result in some clinical and paraclinical characteristics similar to what is seen in multiple sclerosis (MS) patients.
Mohamad Reza Najafi, Vahid Shaygannajad, Maryam Mirpourian, Ali Gholamrezaei   +3 more
doaj  

The effect of Helicobacter pylori on vitamin B 12 blood levels in chronic renal failure patients: A single blind control trial

Saudi Journal of Kidney Diseases and Transplantation, 2013
Helicobacter pylori (HP) is a common infection worldwide and has been associated with severe morbidity. The level of vitamin B 12 in HP-infected chronic kidney disease (CKD) patients is reported to be lower than in the general population.
Hossein Khedmat, Mohsen Amini, Ashraf Karbasi, Reza Azizi   +3 more
doaj   +1 more source

Late onset of symptoms in an atypical patient with the cblJ inborn error of vitamin B-12 metabolism: Diagnosis and novel mutation revealed by exome sequencing

, 2014
Inborn errors of vitamin B-12 (cobalamin) metabolism are characterized by decreased production of active cobalamin cofactors and subsequent deficiencies in the activities of methionine synthase and methylmalonyl-CoA mutase.
Kim, Jaeseung C.;Lee, Ni-Chung;Hwu, Paul Wuh-Liang;Chien, Yin-Hsiu;Fahiminiya, Somayyeh;Majewski, Jacek;Watkins, David;Rosenblatt, David S., 李妮鍾 ;簡穎秀   +1 more
core   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Cobamide Fingerprinting Reveals Nutritional Diversity of Vitamin B₁₂ in Edible Shellfish

Fishes
In edible shellfish, vitamin B12 content has traditionally been evaluated based on total content; however, recent studies reveal substantial diversity in corrinoid composition among species. This review integrates molecular and ecological perspectives to
Fumio Watanabe, Kyohei Koseki, Tomohiro Bito   +2 more
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru, Akansha Chandrasekar, Kyla Blasingame, Jonathan Rosen, Jesse M. Levine, Karla Salazar, Madhuri Chilakapati, Rod Foroozan, Victoria Hardwick, Jonathan M. Yarimi, Nikita Shukla, Timothy E. Lotze, Kristen S. Fisher, Alexander J. Sandweiss   +13 more
wiley   +1 more source

Quantification of vitamin B₁₂ in infant formula by dimensional liquid chromatography with solid phase extraction

浙江大学学报. 农业与生命科学版, 2013
Only a small amount of vitamin B12 is absorbed and utilized by human body. The suitable vitamin B12 levels can improve the utilization efficiency of folic acid. Excessive intake of vitamin B12 may cause allergic reactions, while vitamin B12 deficiency in
CHU Xiaojun, TAO Baohua, LAI Shiyun, ZHANG jingshun, SONG Yiwen, REN Yiping   +5 more
doaj   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Strategy for Optimizing Vitamin B12 Production in Pseudomonas putida KT2440 Using Metabolic Modeling

Metabolites
Background/Objectives: Vitamin B12 is very important for human health, as it is a cofactor for enzymatic activities and plays various roles in human physiology. It is highly valued in the pharmaceutical, food, and additive production industries.
Thomaz Satuye Prieto-de Lima, Keilor Rojas-Jimenez, Christopher Vaglio   +2 more
doaj   +1 more source