Results 91 to 100 of about 320,245 (377)

Nitrous oxide myelopathy with functional vitamin B 12 deficiency

BMJ Case Reports, 2019
Recreational use of nitrous oxide as a ‘legal high’ is increasing in the UK. Physicians should be ‘street wise’ to this increasing prevalence and aware of the potential neurological complications which may result from misuse.
J. Williamson, S. Huda, Dinesh Damodaran
semanticscholar   +1 more source

Cognitive Resilience in Apolipoprotein ε4 Carrier Women Predicted by Neuron‐Derived Extracellular Vesicles

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Apolipoprotein (APOE) ε4 allele is the strongest genetic risk factor for late‐onset Alzheimer's disease (AD); however, many ε4 carriers remain cognitively intact into old age. Leveraging plasma neuron‐derived extracellular vesicles (NDEVs), we sought to identify biomarkers of cognitive resilience and their interplay with APOE ...
Apostolos Manolopoulos, Maja Mustapic, Carlos Nogueras‐Ortiz, Francheska Delgado‐Peraza, Krishna A. Pucha, Pamela J. Yao, Joseph Blommer, Michael P. Vreones, William York, De' Larrian Knight, Stephen R. Rapp, Aladdin H. Shadyab, JoAnn E. Manson, Ramon Casanova, Robert B. Wallace, Luigi Ferrucci, Susan M. Resnick, Dimitrios Kapogiannis   +17 more
wiley   +1 more source

Prevalence of vitamin B12 deficiency in patients treated with metformin [PDF]

Scripta Medica
Background/Aim: Metformin has been associated with vitamin B 12 (cobalamin) deficiency, pushing scientific societies such as the American Diabetes Association and the European Association for the Study of Diabetes to emphasise the need for screening B 12
Peixoto Bruno Daniel Oliveira, Gonçalves Mariana Abreu, da Costa Ana Isabel Ferreira, Gonçalves Eresa Filipa Ramôa   +3 more
doaj   +1 more source

VITAMIN D LEVELS IN PATIENTS WITH CHRONIC HEPATITIS B, CHRONIC HEPATITIS C, AND HEALTH CONTROLS [PDF]

Journal of IMAB, 2019
Purpose: Hepatitis B virus and Hepatitis C virus infection are the most common cause of acute and chronic hepatitis. Over the past decade, numerous studies reported that patients with chronic liver disease, especially HCV-positive and HBV-positive ...
Biljana Ilkovska, Bisera K. Trifunova, Sandra Hristovska, Marina Ivanovska   +3 more
doaj   +1 more source

Screening for metabolic vitamin B₁₂ deficiency by holotranscobalamin in patients suspected of vitamin B₁₂ deficiency: a multicentre study [PDF]

Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2012
Background Vitamin B12 deficiency occurs frequently, especially among the elderly. However, screening for vitamin B12 deficiency is hampered by poor sensitivity of the existing total vitamin B12 assay. Methylmalonic acid (MMA) is considered as the most representative indicator of metabolic vitamin B12 deficiency and is used as such in this study.
Ton Rammeloo, J Maurits M Pekelharing, Maurits C.F.J. de Rotte, Robert de Jonge, Merel van Wijnen, Edward Sanders, Sandra G. Heil, Paul H Trienekens, Anneke C. Muller Kobold, Henk J Adriaansen, Rebecca M R Heiner-Fokkema, Jan Lindemans   +11 more
openaire   +4 more sources

The Regulation of Trace Metal Elements in Cancer Ferroptosis

Advanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang, Yuanyuan Xue, Lei Chang, Xuena Zhu, Wenjun Liu, Tingbo Liang   +5 more
wiley   +1 more source

The effect of Helicobacter pylori on vitamin B 12 blood levels in chronic renal failure patients: A single blind control trial

Saudi Journal of Kidney Diseases and Transplantation, 2013
Helicobacter pylori (HP) is a common infection worldwide and has been associated with severe morbidity. The level of vitamin B 12 in HP-infected chronic kidney disease (CKD) patients is reported to be lower than in the general population.
Hossein Khedmat, Mohsen Amini, Ashraf Karbasi, Reza Azizi   +3 more
doaj   +1 more source

Pancytopenia in pregnant patients with COVID-19 infection and vitamin B12 deficiency: a case report study

Journal of Ideas in Health, 2021
Background: Folate and vitamin B 12 deficiency can lead to pancytopenia in pregnancy. Some cases of pancytopenia due to COVID-19 infection have also been reported.
Neha Agarwal, Neha Khatri, Preeti Singh
doaj   +1 more source

The use of homocysteine and other metabolites in the specific diagnosis of vitamin B-12 deficiency.

Journal of NutriLife, 1996
Vitamin B-12 (cobalamin) is a cofactor for only two enzymes, methionine synthase and L-methylmalonyl-CoA mutase. The serum vitamin B-12 concentration has been shown to have limitations in specificity and sensitivity in diagnosing vitamin B-12 deficiency ...
S. Stabler, J. Lindenbaum, R. Allen
semanticscholar   +1 more source

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

Advanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan, Simona Summonte, Fabrizio Ricci, Matthias Sandmeier, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source