Results 61 to 70 of about 340,270 (377)

Serum vitamin D decreases during chemotherapy: an Australian prospective cohort study [PDF]

, 2018
Background and Objectives: Vitamin D plays an important role in bone and muscle function, and cell prolifera-tion. The impact of chemotherapy and associated behavioural changes such as fatigue and sun avoidance on vit-amin D (25(OH) D) is unknown.
Isenring, Elisabeth, Karapetis, Christos Stelios, Kichenadasse, Ganessan, Kimlin, Michael G, Koczwara, Bogda, Marshall, Skye, Sukumaran, Shawgi, Teleni, Laisa, Walpole, Euan, Woodman, Richard John   +9 more
core   +1 more source

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

FEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura, Lixiang Wang, Nao Hasuzawa, Ayako Nagayama, Sawako Moriyama, Kenji Ashida, Yoshinori Moriyama, Masatoshi Nomura, Ken Yamamoto   +8 more
wiley   +1 more source

Prevalence of vitamin B12 deficiency in type 2 diabetic patients taking metformin, a cross-sectional study in primary healthcare

Frontiers in Endocrinology, 2023
BackgroundSeveral studies documented that metformin use contributes to vitamin B12 deficiency in patients with type 2 diabetes mellitus (T2DM). However, there has been a lack of data assessing this issue in Jordan.AimsAssess the vitamin B12 serum levels,
Thekraiat Al Quran, Ateka Khader, Hadeel Allan, Rua’a Al-Momani, Hamzeh T. Aqel, Mu’taz Alsaleh, Ziad Bataineh, Ziad Bataineh   +7 more
doaj   +1 more source

A life-threatening case of vitamin B 12 deficiency

Journal of Obstetrics and Gynaecology, 2002
Repeat CTG later the same evening revealed recurrent deccelarations from a baseline of 150 bpm down to 120 bpm; there was no uterine activity present. A caesarean section was performed by a consultant obstetrician under general anaesthesia. Thick meconium-stained liquor was present and a 2265 g male infant was delivered with APGARS of 4 and 9 at 1 and ...
J.C.R. Hardwick, E. Walker
openaire   +3 more sources

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Prevalence of vitamin B12 deficiency in patients treated with metformin [PDF]

Scripta Medica
Background/Aim: Metformin has been associated with vitamin B 12 (cobalamin) deficiency, pushing scientific societies such as the American Diabetes Association and the European Association for the Study of Diabetes to emphasise the need for screening B 12
Peixoto Bruno Daniel Oliveira, Gonçalves Mariana Abreu, da Costa Ana Isabel Ferreira, Gonçalves Eresa Filipa Ramôa   +3 more
doaj   +1 more source

Screening for vitamin B-12 and folate deficiency in older persons [PDF]

The American Journal of Clinical Nutrition, 2003
Vitamin B-12 deficiency is usually accompanied by elevated concentrations of serum total homocysteine (tHcy) and methylmalonic acid (MMA). Folate deficiency also results in elevated tHcy. Measurement of these metabolites can be used to screen for functional vitamin B-12 or folate deficiency.We assessed the prevalence of vitamin B-12 and folate ...
Clarke, R., Refsum, H., Birks, J., Evans, J.G., Johnston, C., Sherliker, P., Ueland, P.M., Schneede, J., McPartlin, J., Nexø, Ebba, Scott, J.M.   +10 more
openaire   +5 more sources

Vitamin D supplementation as an adjuvant therapy for patients with T2DM : an 18-month prospective interventional study [PDF]

, 2012
Background Vitamin D deficiency has been associated with impaired human insulin action, suggesting a role in the pathogenesis of diabetes mellitus type 2 (T2DM).
Al-Daghri, Nasser M., Al-Othman, Abdulaziz, Al-Saleh, Yousef, Alkharfy, Khalid M., Alokail, Majed S., Chrousos, George P., El-Kholie, Emad, Kumar, Sudhesh, Moharram, Osama, Sabico, Shaun   +9 more
core   +3 more sources

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source

The effectiveness of vitamin D supplementation in functional outcome and quality of life (QoL) of lumbar spinal stenosis (LSS) requiring surgery

Journal of Orthopaedic Surgery and Research, 2020
Study design This is a retrospective cohort comparative study. Background Vitamin D supplementation is considered to be associated with good functional outcome.
Sangbong Ko, Seungbum Chae, Wonkee Choi, Jaibum Kwon, Je-Yong Choi   +4 more
doaj   +1 more source