Results 61 to 70 of about 1,065,947 (371)

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

Molecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu, Fenglin Shen, Yang Liu, Ziqing Zhong, Yongling Chen, Zhiyuan Xia, Cuiju Mo, Hongxiu Yu   +7 more
wiley   +1 more source

Prevalence of vitamin B12 deficiency in type 2 diabetic patients taking metformin, a cross-sectional study in primary healthcare

Frontiers in Endocrinology, 2023
BackgroundSeveral studies documented that metformin use contributes to vitamin B12 deficiency in patients with type 2 diabetes mellitus (T2DM). However, there has been a lack of data assessing this issue in Jordan.AimsAssess the vitamin B12 serum levels,
Thekraiat Al Quran, Ateka Khader, Hadeel Allan, Rua’a Al-Momani, Hamzeh T. Aqel, Mu’taz Alsaleh, Ziad Bataineh, Ziad Bataineh   +7 more
doaj   +1 more source

Efficient synthesis of Vitamin D3 in a 3D ultraviolet photochemical microreactor fabricated using an ultrafast laser [PDF]

arXiv, 2023
Large-scale, high-precision, and high-transparency microchannels hold great potential for developing high-performance continuous-flow photochemical reactions. We demonstrate ultrafast laser-enabled fabrication of 3D microchannel reactors in ultraviolet (UV) grade fused silica which exhibit high transparency under the illumination of UV light sources of
arxiv  

Modeling a methylmalonic acid–derived change point for serum vitamin B-12 for adults in NHANES [PDF]

, 2013
Background: No consensus exists about which cutoff point should be applied for serum vitamin B-12 (SB-12) concentrations to define vitamin B-12 status in population-based research.
Alicia Carriquiry, Bailey, Bailey, Carmel, Carmel, Christine M Pfeiffer, Christopher T Sempos, Clarke, Cleveland, Cleveland, Elizabeth A Yetley, Food and Nutrition Board, Green, Kim, Kolenikov, Lerman, Lloyd-Wright, Miller, Oussalah, Pennypacker, Pfeiffer, Ralph Carmel, Ralph Green, Ramon A Durazo-Arvizu, Refsum, Regan L Bailey, Selhub, Selvin, Smith, Vogiatzoglou, Yetley   +30 more
core   +3 more sources

Clinical Phenotyping of Long COVID Patients Evaluated in a Specialized Neuro‐COVID Clinic

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To report Long COVID characteristics and longitudinal courses of patients evaluated between 4/14/21–4/14/22 at the University of Pennsylvania Neurological COVID Clinic (PNCC), including clinical symptoms, neurological examination findings, and neurocognitive screening tests from a standardized PNCC neurological evaluation approach ...
Luana D. Yamashita, Neel Desai, Abigail R. Manning, Caitlin Pileggi, Sara Manning Peskin, Danielle K. Sandsmark, Dennis L. Kolson, Matthew K. Schindler   +7 more
wiley   +1 more source

A life-threatening case of vitamin B 12 deficiency

Journal of Obstetrics and Gynaecology, 2002
Repeat CTG later the same evening revealed recurrent deccelarations from a baseline of 150 bpm down to 120 bpm; there was no uterine activity present. A caesarean section was performed by a consultant obstetrician under general anaesthesia. Thick meconium-stained liquor was present and a 2265 g male infant was delivered with APGARS of 4 and 9 at 1 and ...
J.C.R. Hardwick, E. Walker
openaire   +3 more sources

Screening for vitamin B-12 and folate deficiency in older persons [PDF]

The American Journal of Clinical Nutrition, 2003
Vitamin B-12 deficiency is usually accompanied by elevated concentrations of serum total homocysteine (tHcy) and methylmalonic acid (MMA). Folate deficiency also results in elevated tHcy. Measurement of these metabolites can be used to screen for functional vitamin B-12 or folate deficiency.We assessed the prevalence of vitamin B-12 and folate ...
Clarke, R., Refsum, H., Birks, J., Evans, J.G., Johnston, C., Sherliker, P., Ueland, P.M., Schneede, J., McPartlin, J., Nexø, Ebba, Scott, J.M.   +10 more
openaire   +5 more sources

The Masking Effect: A comparison of pre and post folic acid fortification periods for vitamin B-12 deficiency without macrocytosis in the United States [PDF]

, 2014
Background: There has been a concern regarding the masking of vitamin B-12 deficiency in the post-fortification period (after January 1, 1998). Objective: The objective of this study was to investigate the potential masking of vitamin B-12 deficiency by ...
Steele, Benjamin D
core   +1 more source

The Impact of Diabetes and Metabolic Syndrome Burden on Pain, Neuropathy Severity and Fiber Type

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Determine the association between diabetes and metabolic syndrome (MetS) burden (number of MetS criteria fulfilled) and pain, neuropathy severity, and fiber type involvement in individuals with established polyneuropathy. Methods The Peripheral Neuropathy Research Registry was queried for individuals with type 1 and type 2 diabetes ...
Long Davalos, Brian C. Callaghan, Lavanya Muthukumar, Simone Thomas, Evan L. Reynolds, A. Gordon Smith, J. Robinson Singleton, Ahmet Höke, Senda Ajroud‐Driss, Mazen M. Dimachkie, Stefanie Geisler, David M. Simpson, PNRR Study Group, Amro M. Stino   +13 more
wiley   +1 more source

The effectiveness of vitamin D supplementation in functional outcome and quality of life (QoL) of lumbar spinal stenosis (LSS) requiring surgery

Journal of Orthopaedic Surgery and Research, 2020
Study design This is a retrospective cohort comparative study. Background Vitamin D supplementation is considered to be associated with good functional outcome.
Sangbong Ko, Seungbum Chae, Wonkee Choi, Jaibum Kwon, Je-Yong Choi   +4 more
doaj   +1 more source