Results 51 to 60 of about 458,356 (312)

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

Development and Validation of a Quantitative Analysis of Water-Soluble Vitamins Using High-Performance Thin-Layer Chromatography and Its Application to the Analysis of Nutraceuticals

Separations
In this study, a high-performance thin-layer chromatography (HPTLC)-based method was developed for the quantification of five water-soluble vitamins, B2, B3, B6, B12, and C, using ethanol–water (70:30, v/v) as the mobile phase.
K. M. Yasif Kayes Sikdar, Md Khairul Islam, Tomislav Sostaric, Lee Yong Lim, Cornelia Locher   +4 more
doaj   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Functional Improvement in Geriatric Hip Fractures

Geriatric Orthopaedic Surgery & Rehabilitation, 2015
Introduction: The “Integrated Care Pathway” for geriatric intertrochanteric (IT) fractures in Singapore’s Tan Tock Seng Hospital has shown significant functional recovery in patients’ activities of daily living.
W. R. D. Seng MBChB, MRCS(Glasg), M. H. Belani, R. Ramason MBChB (Leeds), MRCP (UK), DGM (London), G. Naidu MBBS, FRCS (Edin), FRCS (Edin) (Ortho), FAMS (Ortho), H. K. Doshi Bac. Med. Sc, M.D. (M'sia), MRCS (Ed), AFRCSI (Dublin), FRCS Ed (Ortho), FEBOT (Europe), M.Med.Ortho (S'pore), Dip SICOT (Belgium)   +4 more
doaj   +1 more source

Effect of vitamin D on the pregnancy and the health of newborns and infants: state-of-the-art [PDF]

РМЖ. Мать и дитя, 2020
I.N. Zakharova1, S.V. Mal’tsev1, V.V. Zubkov2, V.A. Kur’yaninova3, A.V. Dmitriev4, L.I. Mal’tseva5, N.E. Verisokina3, L.Ya. Klimov3, E.N. Vasil’eva6, S.I. Malyavskaya7, A.L.
I.N. Zakharova, S.V. Mal’tsev, V.V. Zubkov, V.A. Kur’yaninova, A.V. Dmitriev, L.I. Mal’tseva, N.E. Verisokina, L.Ya. Klimov, E.N. Vasil’eva, S.I. Malyavskaya, A.L. Zaplatnikov   +10 more
doaj  

Blood plasma B vitamins in depression and the therapeutic response to electroconvulsive therapy

Brain, Behavior, & Immunity - Health, 2020
A growing body of research has indicated a role for B vitamins in depression, with some previous studies suggesting that B vitamin status in patients with depression can impact on antidepressant response.
Karen M. Ryan, Kelly A. Allers, Andrew Harkin, Declan M. McLoughlin   +3 more
doaj   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Detectable Unmetabolized Folic Acid and Elevated Folate Concentrations in Folic Acid-Supplemented Canadian Children With Sickle Cell Disease

Frontiers in Nutrition, 2021
Sickle cell disease (SCD) is an inherited hemoglobinopathy caused by a variant (rs344) in the HBB gene encoding the β-globin subunit of hemoglobin. Chronic hemolytic anemia and increased erythropoiesis and RBC turnover in individuals with SCD can result ...
Brock A. Williams, Brock A. Williams, Cara Mayer, Cara Mayer, Heather McCartney, Angela M. Devlin, Angela M. Devlin, Yvonne Lamers, Yvonne Lamers, Suzanne M. Vercauteren, Suzanne M. Vercauteren, John K. Wu, John K. Wu, Crystal D. Karakochuk, Crystal D. Karakochuk   +14 more
doaj   +1 more source

Clinical use of cyclooxygenase inhibitors impairs vitamin B-6 metabolism

, 2014
Background: A low circulating vitamin B-6 concentration, which is an independent risk factor for cardiovascular disease, is commonly seen in human inflammation.Objective: We investigated whether cyclooxygenase inhibitors alter vitamin B-6 metabolism ...
Lan JL, Chiang EP, Chih HM, Tang FY, Huang ST, Chang HY, Chen DY, Cheng HD   +7 more
core   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source