Results 51 to 60 of about 20,924,698 (293)

Functional Improvement in Geriatric Hip Fractures

Geriatric Orthopaedic Surgery & Rehabilitation, 2015
Introduction: The “Integrated Care Pathway” for geriatric intertrochanteric (IT) fractures in Singapore’s Tan Tock Seng Hospital has shown significant functional recovery in patients’ activities of daily living.
W. R. D. Seng MBChB, MRCS(Glasg), M. H. Belani, R. Ramason MBChB (Leeds), MRCP (UK), DGM (London), G. Naidu MBBS, FRCS (Edin), FRCS (Edin) (Ortho), FAMS (Ortho), H. K. Doshi Bac. Med. Sc, M.D. (M'sia), MRCS (Ed), AFRCSI (Dublin), FRCS Ed (Ortho), FEBOT (Europe), M.Med.Ortho (S'pore), Dip SICOT (Belgium)   +4 more
doaj   +1 more source

Effect of vitamin D on the pregnancy and the health of newborns and infants: state-of-the-art [PDF]

РМЖ. Мать и дитя, 2020
I.N. Zakharova1, S.V. Mal’tsev1, V.V. Zubkov2, V.A. Kur’yaninova3, A.V. Dmitriev4, L.I. Mal’tseva5, N.E. Verisokina3, L.Ya. Klimov3, E.N. Vasil’eva6, S.I. Malyavskaya7, A.L.
I.N. Zakharova, S.V. Mal’tsev, V.V. Zubkov, V.A. Kur’yaninova, A.V. Dmitriev, L.I. Mal’tseva, N.E. Verisokina, L.Ya. Klimov, E.N. Vasil’eva, S.I. Malyavskaya, A.L. Zaplatnikov   +10 more
doaj  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Proxy markers of serum retinol concentration, used alone and in combination, to assess population vitamin A status in Kenyan children: a cross-sectional study [PDF]

, 2015
Background Serum retinol concentration determined by high-performance liquid chromatography (HPLC) is recommended by the World Health Organization to assess population vitamin A status.
Inge D Brouwer, Verhoef, H., Elise F Talsma, Alida Melse-Boonstra, Brouwer, Inge D, Hulshof, Paul JM, Talsma, E.F., Anne S Mburu-de Wagt, Paul JM Hulshof, Hans Verhoef, Talsma, Elise F, Mburu-de Wagt, Anne S, Melse-Boonstra, Alida, Brouwer, I.D., Hulshof, P.J.M., Mburu-de Wagt, A.S., Verhoef, Hans, Boonstra, A., Talsma, E.F.; Verhoef, H.; Brouwer, I.D.; Mburu-de Wagt, A.S.; Hulshof, P.J.M.; Melse-Boonstra, A.   +18 more
core   +2 more sources

Blood plasma B vitamins in depression and the therapeutic response to electroconvulsive therapy

Brain, Behavior, & Immunity - Health, 2020
A growing body of research has indicated a role for B vitamins in depression, with some previous studies suggesting that B vitamin status in patients with depression can impact on antidepressant response.
Karen M. Ryan, Kelly A. Allers, Andrew Harkin, Declan M. McLoughlin   +3 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Adjunctive Multicomponent Crystals of Two Anti-Tubercular Drugs with Pyridoxine

Pharmaceutics
Background/Objectives: Cocrystallisation is a well-established path for altering the physicochemical properties and bioavailability of active pharmaceutical ingredients (APIs). A common side effect of anti-tubercular medicines is the depletion of group B
Tsebang A. Matlapeng, Theodor E. Geswindt, Roderick B. Walker, Vincent J. Smith   +3 more
doaj   +1 more source

Biosynthesis of Vitamin B6

Journal of Biological Chemistry, 1972
The biosynthesis of vitamin B6 was studied in an Escherichia coli mutant, blocked between pyridoxol and pyridoxal. Specific incorporation of glycerol, pyruvate, serine, and glucose was shown by chemical degradation of labeled samples of pyridoxol isolated from the medium of cultures which had been incubated with various 14C-labeled radiomers of these ...
R E, Hill, F J, Rowell, R N, Gupta, I D, Spenser   +3 more
openaire   +2 more sources

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Inflammation causes tissue-specific depletion of vitamin B-6 [PDF]

, 2005
Previously we observed strong and consistent associations between vitamin B-6 status and several indicators of inflammation in patients with rheumatoid arthritis.
Selhub, J., Roubenoff, Ronenn, Chiang, Eugene, Chiang, E.P., Smith, D.E., Smith, Donald, Selhub, Jacob, Roubenoff, R., Dallal, Gerard, Wang, Yi-Cheng, Dallal, G., Wang, Y.C.   +11 more
core   +1 more source