Results 91 to 100 of about 452,665 (337)
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth+2 more
wiley +1 more source
This review highlights emerging bioengineering strategies for treating neointimal hyperplasia in the peripheral vasculature, focusing on approaches that promote re‐endothelialization, modulate smooth muscle cell phenotype, reduce inflammation, mitigate oxidative stress, and optimize biomechanical compliance.
Nikita Wilson John+5 more
wiley +1 more source
Complications in diabetes mellitus: diabetic neuropathy focus
The article deals with one of the frequent complications in diabetes mellitus diabetic neuropathy, which is associated with early disability of patients and an impaired quality of life. Distal neuropathy is the most common clinical form of diabetes.
E. V. Biryukova
doaj +1 more source
Rumen Synthesis of the Vitamin B Complex.
Work reported by McElroy and Gross1 indicates the ability of sheep to synthesize several members of the vitamin B complex in the rumen. Significant increases in the vitamin content of rumen ingesta were found in comparison to the amounts in the ration fed. The vitamins determined were thiamin, riboflavin, pyridoxine, and pantothenic acid.
M.I. Wegner+3 more
openaire +2 more sources
Holotranscobalamin, a marker of vitamin B-12 status: analytical aspects and clinical utility12345 [PDF]
Approximately one-quarter of circulating cobalamin (vitamin B-12) binds to transcobalamin (holoTC) and is thereby available for the cells of the body. For this reason, holoTC is also referred to as active vitamin B-12.
Aarsetøy+62 more
core +2 more sources
Role of vitamin A/retinoic acid in regulation of embryonic and adult hematopoiesis [PDF]
Vitamin A is an essential micronutrient throughout life. Its physiologically active metabolite retinoic acid (RA), acting through nuclear retinoic acid receptors (RARs), is a potent regulator of patterning during embryonic development, as well as being ...
Adamo+23 more
core +4 more sources
Lipid Nanoparticle‐Mediated CRISPR‐Cas13a Delivery for the Control of Bacterial Infection
New formulations of lipid nanoparticles (LNPs) that can deliver nucleic acids to Gram‐negative bacteria are proposed to combat bacterial infection. The delivery of nucleic acids by LNPs is aided by LNP‐helpers which weaken the bacterial outer membrane. LNPs encapsulating the Cas13a/gRNA expression vector achieve an antibacterial effect in both in vivo ...
Bookun Kim+9 more
wiley +1 more source
Vitamin B Complex and Gastric Secretion
Webster and Armour1 reported that artificially fed dogs with oesophagotomy, gastric fistula, obstructed pylorus and duodenal fistula, in which a condition of practically total avitaminosis had been induced, developed a complete achlorhydria without anorexia and inanition.
D. R. Webster, J. C. Armour
openaire +2 more sources
Cognitive tests used in chronic adult human randomised controlled trial micronutrient and phytochemical intervention studies [PDF]
In recent years there has been a rapid growth of interest in exploring the relationship between nutritional therapies and the maintenance of cognitive function in adulthood.
Anderson+28 more
core +1 more source
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto+2 more
wiley +1 more source