Vitamin B-12 deficiency stimulates osteoclastogenesis via increased homocysteine and methylmalonic acid [PDF]
The risk of nutrient deficiencies increases with age in our modern Western society, and vitamin B(12) deficiency is especially prevalent in the elderly and causes increased homocysteine (Hcy) and methylmalonic acid (MMA) levels.
Bravenboer, N. +37 more
core +1 more source
A randomised controlled trial investigating the effect of vitamin B12 supplementation on neurological function in healthy older people: the Older People and Enhanced Neurological function (OPEN) study protocol [ISRCTN54195799]. [PDF]
BACKGROUND: Vitamin B12 deficiency is common in older people and the prevalence increases with age. Vitamin B12 deficiency may present as macrocytic anaemia, subacute combined degeneration of the spinal cord, or as neuropathy, but is often asymptomatic ...
Allen, Elizabeth +32 more
core +1 more source
Blood levels of vitamin C, carotenoids and retinol are inversely associated with cataract in a north Indian population [PDF]
PURPOSE: To examine the association of blood antioxidants with cataract. METHODS: Cross-sectional study of people aged >or=50 years identified from a household enumeration of 11 randomly sampled villages in North India.
Price, Gill M. +14 more
core +1 more source
In glucose-6-phosphate-dehydrogenase deficiency (favism), exposure to oxidant agents can trigger hemolytic crises. The intravenous administration of very high doses of vitamin C was proposed as a treatment for severe coronavirus disease 2019 (COVID-19 ...
Filippo Luca Fimognari +6 more
doaj +1 more source
A genetic validation study reveals a role of vitamin D metabolism in the response to interferon-alfa-based therapy of chronic hepatitis C [PDF]
Background: To perform a comprehensive study on the relationship between vitamin D metabolism and the response to interferon-α-based therapy of chronic hepatitis C.
Jörg Bojunga +66 more
core +1 more source
Vitamin C Deficiency in an Anticoagulated Patient [PDF]
A 64-year-old woman presented with a hemorrhagic perifollicular rash on her legs while taking warfarin. After biopsy, vitamin C deficiency was suggested as the diagnosis, which ascorbic acid assays later confirmed. Clinical resolution of the rash followed supplementation with vitamin C.
George M, Yousef, Lynne J, Goebel
openaire +2 more sources
Association Between Vitamin Deficiencies and Ophthalmological Conditions
Austin Pereira,1 R Damilola Adekunle,2,* Michele Zaman,3,* Michael J Wan1 1University of Toronto Department of Ophthalmology & Vision Sciences, Toronto, Ontario, Canada; 2Faculty of Medicine, Memorial University of Newfoundland, St.
Pereira A, Adekunle RD, Zaman M, Wan MJ
doaj
Background Hypovitaminosis C and vitamin C deficiency are common in critically ill patients and associated with organ dysfunction. Low vitamin C status often goes unnoticed because determination is challenging.
Sander Rozemeijer +5 more
doaj +1 more source
Vitamin C and D Deficiency in Urban America: A Case Report
Introduction: Scurvy is caused by vitamin C deficiency and manifests with a variety of symptoms including generalized fatigue, apathy, anemia, myalgias, easy bruising, and poor wound healing.
Alyssa A. Lombardi +2 more
doaj +1 more source
Association between MTHFR 677C>T polymorphism and vitamin B12 deficiency: A case-control study [PDF]
Background: Vitamin B12 (cobalamin) deficiency is a prevalent worldwide health concern. Several factors are associated with vitamin B12 deficiency including lifestyle, genetic predisposition, and malfunctions in the absorption and transport of vitamin ...
Al-Batayneh Khalid M. +8 more
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