Results 41 to 50 of about 181,889 (303)

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Regulation of Vitamin C Homeostasis during Deficiency [PDF]

Nutrients, 2013
Large cross-sectional population studies confirm that vitamin C deficiency is common in humans, affecting 5%–10% of adults in the industrialized world. Moreover, significant associations between poor vitamin C status and increased morbidity and mortality have consistently been observed.
Maiken Lindblad, Pernille Tveden-Nyborg, Jens Lykkesfeldt   +2 more
openaire   +3 more sources

Tuberculosis incidence correlates with sunshine : an ecological 28-year time series study [PDF]

, 2013
Birmingham is the largest UK city after London, and central Birmingham has an annual tuberculosis incidence of 80 per 100,000. We examined seasonality and sunlight as drivers of tuberculosis incidence. Hours of sunshine are seasonal, sunshine exposure is
Martin Dedicoat, Kunst, Heinke, Gavin C K W Koh, Hawthorne Gemma, Koh, Gavin, Hawthorne, Gemma, Koh, Gavin C K W, Turner, AM, Koh, GCKW, Hawthorne, G, Turner, Alice M., Turner Alice M., Alice M Turner, Turner, Alice M, Dedicoat Martin, Dedicoat, Martin, Gemma Hawthorne, Dedicoat, M, Koh Gavin C. K. W., Kunst Heinke, Heinke Kunst, Kunst, H   +21 more
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

Comparative analysis of vitamin D contents in patients with chronic viral hepatitis C and healthy.

Medičnì Perspektivi, 2019
From scientific literature it is known that vitamin D helps maintain the most important functions of the immune system, there is evidence of its role in inflammatory and metabolic diseases of the liver, including infection with hepatitis C.
L. L. Shostakovych-Koretskaya, M. A. Nikolaychuk, I. V. Budayeva, O. P. Shevchenko-Makarenko, K. Yu. Lytviy, S. V. Biletska   +5 more
doaj   +1 more source

Prevalence of vitamin B12 insufficiency during pregnancy and its effect on offspring birthweight: a systematic review and meta-analysis. [PDF]

, 2016
Background: Vitamin B-12 and folate are micronutrients essential for normal embryogenesis. Vitamin B-12 insufficiency in pregnancy is high in certain parts of the world, such as India, and although this has been linked to low birth weight (LBW) in these ...
Rafnsson, Snorri B., Kandala, Ngianga-Bakwin, Saravanan, Ponnusamy, Yajnik, Chittaranjan, Sukumar, Nithya, Rafnsson, Snorri B, Bhopal, Raj, Yajnik, Chittaranjan S., Rafnsson, Snorri, Yajnik, Chittaranjan S   +9 more
core   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Scurvy with Musculoskeletal Pain in Indonesian Pediatric Patient: A Case Report

Jurnal Kedokteran Diponegoro
Background: Scurvy is a potentially fatal disease caused by a severe deficiency of vitamin C, which can manifest as a musculoskeletal problem. Early diagnosis and treatment of vitamin C deficiency are crucial to prevent severe symptoms.
Hilmi Muhammad, Meirizal Meirizal, Yudha Mathan Sakti, Aditya Fuad Robby Triangga, Zikrina Abiyanti Lanodiyu, Ginanjar Reza Putra, Yasser Yasser, Yuni Artha Prabowo Putro   +7 more
doaj   +1 more source

Vitamin D supplementation as an adjuvant therapy for patients with T2DM : an 18-month prospective interventional study [PDF]

, 2012
Background Vitamin D deficiency has been associated with impaired human insulin action, suggesting a role in the pathogenesis of diabetes mellitus type 2 (T2DM).
Al-Othman, Abdulaziz, Osama Moharram, Alokail Majed S, El-Kholie, Emad, Kumar Sudhesh, Sabico, Shaun, Sudhesh Kumar, Sabico Shaun, George P Chrousos, Al-Othman Abdulaziz, Alokail, Majed S., Al-Daghri, Nasser M., Al-Saleh, Yousef, Majed S Alokail, Al-Saleh Yousef, Yousef Al-Saleh, Alkharfy Khalid M, Chrousos, George P., Kumar, Sudhesh, Chrousos George P, Abdulaziz Al-Othman, Emad El-Kholie, Moharram Osama, Nasser M Al-Daghri, Shaun Sabico, El-Kholie Emad, Moharram, Osama, Al-Daghri Nasser M, Alkharfy, Khalid M., Khalid M Alkharfy   +29 more
core   +1 more source