Results 51 to 60 of about 19,174,629 (255)

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

The role of inflammation and oxidative stress in the pathophysiology of depressions: time to consider vitamin C deficiency

Exploration of Neuroscience
Depression is on the rise and medication does not always provide satisfactory relief. This raises the question of a treatment gap that has not yet been (sufficiently) addressed. Inflammation and oxidative stress play an important pathophysiological role,
Claudia Vollbracht, Marc Werner
doaj   +1 more source

Proceedings of the Rank Forum on Vitamin D [PDF]

, 2010
The Rank Forum on Vitamin D was held on 2nd and 3rd July 2009 at the University of Surrey, Guildford, UK. The workshop consisted of a series of scene-setting presentations to address the current issues and challenges concerning vitamin D and health, and ...
Lamberg-Allardt, C, C. Nowson, Martineau, A.R., Miles, LM, Lamberg-Allardt, C., Martineau, AR, Darling, A. L., Macdonald, H M, H. M. Macdonald, Berry, J.L., A. L. Darling, Fraser, WD, S. Reddy, M. Kiely, Darling, A.L., de Groot, CPGM, Macdonald, H. M., C. P. G. M. de Groot, S. A. Lanham-New, Prentice, A., Mavroeidi, A.; id_orcid, de Groot, C P G M, Kiely, M., Stone, E M, Fraser, W. D., Miles, L.M., Macdonald, HM, Lanham-New, S. A., Masud, T, De Groot, C. P.G.M., A. Prentice, Francis, R.M., Vieth, R, Francis, RM, K. D. Cashman, Masud, T., E. Hyppönen, Williams, C. M., Boucher, BJ, de Groot, C.P.G.M., Williams, Christine Mary, Mavroeidi, A., Buttriss, J L, de Groot, C. P. G. M., Boucher, B.J., Mavroeidi, A, Reddy, S., A. Mavroeidi, Nowson, C., Stone, E.M., Cooper, C., W. D. Fraser, Fraser, W D, Cooper, C, A. R. Martineau, Boucher, B. J., Berry, J L, E. M. Stone, Buttriss, J.L., C. Cooper, Francis, R. M., Stone, EM, Williams, CM, Reddy, S, Kiely, K, Kiely, M, Hyppönen, E, T. Masud, Martineau, A. R., Francis, R M, Lanham-New, SA, Vieth, R., C. M. Williams, Hyppönen, E., Prentice, A, Macdonald, H.M., B. J. Boucher, M. Ashwell, Williams, M., J. L. Berry, Ashwell, M., Buttriss, JL, Fraser, W.D., L. M. Miles, Miles, L. M., Nowson, C, Stone, E. M., Cashman, K.D., Lanham-New, S A, C. Lamberg-Allardt, Cashman, K D, Berry, J. L., Berry, J.L, Miles, L M, Cashman, K. D., Ashwell, M, Darling, A L, Buttriss, J. L., J. L. Buttriss, Cashman, KD, de Groot, C.P., R. Vieth, Darling, AL, Williams, C.M., Berry, JL, Lanham-New, S.A., Boucher, B J, Groot, C.P.G.M., de, R. M. Francis, Williams, C M, Martineau, A R, Hypöpnen, E., Hyppöpnen, E., Lanham New, S.A.   +113 more
core   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Vitamin C deficiency can lead to pulmonary hypertension: a systematic review of case reports

BMC Pulmonary Medicine
Background In the early literature, unintentional vitamin C deficiency in humans was associated with heart failure. Experimental vitamin C deficiency in guinea pigs caused enlargement of the heart.
Harri Hemilä, Angelique M.E. de Man
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Scurvy in the Intensive Care Unit

Journal of Investigative Medicine High Impact Case Reports, 2021
Scurvy, caused by vitamin C deficiency, is a forgotten disease in the modern era of medicine. The prevalence of vitamin C deficiency in the United States is reported to be 7.1%. We present a case of a 56-year-old man with a history of chronic alcohol use
Amarah Baluch MD, David Landsberg MD
doaj   +1 more source

Effect of vitamin D deficiency on surgical outcomes of degenerative cervical myelopathy

North American Spine Society Journal, 2023
: Background: Due to its association with bone metabolic status and muscle strength/mass, vitamin D deficiency has the potential to affect neurological symptom recovery after surgery for degenerative cervical myelopathy (DCM).
Hiroyuki Inose, MD, PhD, Takuya Takahashi, MD, Yu Matsukura, MD, PhD, Jun Hashimoto, MD, PhD, Kurando Utagawa, MD, PhD, Satoru Egawa, MD, PhD, Kentaro Yamada, MD, PhD, Takashi Hirai, MD, PhD, Kunihiko Takahashi, PhD, Toshitaka Yoshii, MD, PhD   +9 more
doaj   +1 more source

Micronutrient malnutrition and wasting in adults with pulmonary tuberculosis with and without HIV co-infection in Malawi. [PDF]

, 2004
BACKGROUND: Wasting and micronutrient malnutrition have not been well characterized in adults with pulmonary tuberculosis. We hypothesized that micronutrient malnutrition is associated with wasting and higher plasma human immunodeficiency virus (HIV ...
Johnny J Kumwenda, Tamara D Clark, Richard D Semba, Harries Anthony D, Zijlstra, Ed E, Clark Tamara D, Taha Taha E, Taha, Taha E, Kumwenda, Johnny J, Semba Richard D, Anthony D Harries, Kumwenda Johnny J, Zijlstra Ed E, Harries, Anthony D, Monique van Lettow, Taha E Taha, Clark, Tamara D, van Lettow Monique, van Lettow, Monique, Ed E Zijlstra, Semba, Richard D   +20 more
core   +2 more sources

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source