Results 111 to 120 of about 149,521 (328)

Natural Products Targeting Notch Signaling in Cancer: Mechanistic Insights and Food‐Based Chemoprevention Potential

Food Frontiers, EarlyView.
The Notch signaling pathway plays a dual role in cancer, acting as both a tumor promoter and suppressor depending on cellular context. This review highlights how natural products modulate Notch signaling to inhibit tumor initiation, progression, angiogenesis, and cancer stem cell maintenance.
Rabab Fatima, Parteek Prasher, Mousmee Sharma, Dietrich Büsselberg, Gabriela Figueroa‐González, Octavio Daniel Reyes‐Hernández, Edgar Yebrán Villegas‐Vázquez, Hernán Cortés, Gerardo Leyva‐Gómez, Jesús Herrera‐Bravo, Solomon Habtemariam, Javad Sharifi‐Rad, Monica Butnariu, Cristian Berar, Angela Caunii, William C. Cho   +15 more
wiley   +1 more source

Weekly High Dose Versus Daily Low Dose Vitamin D3 in Treatment of Vitamin D3 Deficiency in Pregnancy: A Randomized Controlled Clinical Trial

Journal of Family and Reproductive Health, 2019
Objective: To compare administration of weekly high dose versus daily low dose vitamin D3 in treatment of vitamin D3 deficiency in pregnancy. Materials and methods: A randomized controlled clinical trial was performed between July 2016 until 2 July 2017 ...
Farahnaz Rostami, Lida Moghaddam Banaem, Sedigheh Hantoushzadeh   +2 more
doaj  

Effects of a multi-component exercise program and calcium–vitamin-D3-fortified milk on bone mineral density in older men : a randomised controlled trial

, 2009
Summary We examined the independent and combined effects of a multi-component exercise program and calcium–vitamin-D3-fortified milk on bone mineral density (BMD) in older men.
Bass, S., Daly, R., Kukuljan, S., Nicholson, G., Nowson, C., Salmon, J., Sanders, K., Seibel, M.   +7 more
core   +1 more source

CYP24A1 inhibition facilitates the anti-tumor effect of vitamin D3 on colorectal cancer cells [PDF]

, 2013
AIM: The effects of vitamin D3 have been investigated on various tumors, including colorectal cancer (CRC). 25-hydroxyvitamin-D3-24-hydroxylase (CYP24A1), the enzyme that inactivates the active vitamin D3 metabolite 1,25-dihydroxyvitamin D3 (1,25-D3), is
Balla Bernadett, Horváth Evelin, Horváth Henrik Csaba, Horváth P, Kovács Dóra Irén, Kósa János, Lakatos Péter, Mátyus Péter, Nagy Zsolt, Speer Gábor, Takács István, Wölfling János   +11 more
core   +1 more source

Effects of vitamin D2-fortified bread v. supplementation with vitamin D2 or D3 on serum 25-hydroxyvitamin D metabolites: an 8-week randomised-controlled trial in young adult Finnish women [PDF]

, 2016
There is a need for food-based solutions for preventing vitamin D deficiency. Vitamin D3(D3) is mainly used in fortified food products, although the production of vitamin D2(D2) is more cost-effective, and thus may hold opportunities. We investigated the
Cashman, Kevin D., Erkkola, Maijaliisa, Itkonen, Suvi T., Jakobsen, Jette, Lamberg-Allardt, Christel, Saaristo, Pilvi, Saarnio, Elisa M., Skaffari, Essi   +7 more
core   +1 more source

Predictors of 25(OH)D half-life and plasma 25(OH)D concentration in The Gambia and the UK [PDF]

, 2014
Summary: Predictors of 25(OH)D3 half-life were factors associated with vitamin D metabolism, but were different between people in The Gambia and the UK.
A Prentice, A. Prentice, AJ Batchelor, AJ Batchelor, AJ Brown, B Casetta, C Prynne, D Vanderschueren, D Vicchio, D Wagner, D. Vanderschueren, E Fitt, E Gravesen, EB Mawer, I Schoenmakers, I Schoenmakers, I. Schoenmakers, IOM, JE Smith, K. S. Jones, KA Young, KS Jones, KS Jones, L Haddock, M Abboud, M Davies, MR Clements, MR Clements, MR Clements, PH Anderson, R Bouillon, R Bouillon, R Bouillon, R. Bouillon, RF Chun, RW Gray, S. Assar, UK Møller, V Braithwaite   +38 more
core   +2 more sources

24R,25(OH)2D3 regulates tumorigenesis in estrogen sensitive laryngeal cancer cells via membrane‐associated receptor complexes in ER+ and ER− cells

International Journal of Cancer, EarlyView.
What's New? Estrogen receptors likely influence the development of laryngeal cancer and are of particular interest in regard to their relationship with the vitamin D metabolite 24R,25(OH)2D3. In this study the authors examined interactions between 24R,25(OH)2D3 and estrogen‐responsive laryngeal tumorigenesis.
Cydney D. Dennis, D. Joshua Cohen, Kusal Debnath, Nofrat Schwartz, Brock P. Lodato, Jonathan T. Dillon, Tillat Batool, Matthew S. Halquist, Preetam Ghosh, Zvi Schwartz, Barbara D. Boyan   +10 more
wiley   +1 more source

Electronic structure of vitamins D2 and D3

Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1997
AbstractThe electronic structures of vitamins D2 and D3 were studied by He I photoelectron spectroscopy (UPS) and semi-empirical AM1 MO calculations. The analysis of electronic structure reveals two important facts. The vitamin D compounds have electronic structures which resemble steroid hormones and not other vitamins.
Novak, I., Potts, A.W.
openaire   +3 more sources

Effects Of Papaya Leaf Meal, Pineapple Skin Meal And Vitamin D3 Supplements On Meat Quality Of Spent Layer Hens [PDF]

, 2010
A study was conducted to evaluate the effects of supplementation of vitamin D3, papaya leaf meal (PLM) and pineapple skin meal (PSM) for 7 days prior to slaughter on meat quality of spent layer chickens. In Experiment 1, based on Completely Randomized
Navid, Saeid
core  

Vitamin D supplementation does not improve human skeletal muscle contractile properties in insufficient young males [PDF]

, 2014
Vitamin D may be a regulator of skeletal muscle function, although human trials investigating this hypothesis are limited to predominantly elderly populations.
Close, Graeme L, Donovan, Timothy F, Fraser, William D, Impey, Samuel G, Morton, James P, Owens, Daniel J, Tang, Jonathan, Webber, Daniel   +7 more
core   +1 more source