Results 151 to 160 of about 479,304 (279)

Human breast milk lipoproteins: A preliminary biochemical characterization

open access: yesExperimental Physiology, EarlyView.
Abstract Human breast milk (BM) is an essential fluid for infant development, with a dynamic composition adapted to the infant's needs. It contains bioactive lipids like cholesterol, typically transported by lactosomes, extracellular vesicles, and milk fat globules. However, classic cholesterol‐carrying lipoproteins have not been described in BM.
Gabriela Arenas   +3 more
wiley   +1 more source

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor   +4 more
wiley   +1 more source

Minimally processed, human‐grade diet alters canine epigenetic ageing: Results from a pilot study

open access: yesVeterinary Record Open, Volume 13, Issue 2, December 2026.
Abstract Background Diet plays a critical role in promoting wellness and longevity in both humans and canines. Epigenetic ageing clocks have emerged as accurate tools for assessing biological ageing and evaluating dietary and lifestyle interventions in humans and mice.
Aimee Chen   +5 more
wiley   +1 more source

Consensus Guidelines for Diagnosis and Management of Pyruvate Dehydrogenase Complex Deficiency

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.
ABSTRACT Primary pyruvate dehydrogenase complex deficiency (PDCD) comprises a group of monogenic disorders caused by pathogenic variants in genes encoding subunits of, or regulatory components affecting, the pyruvate dehydrogenase complex. The clinical phenotype spans a broad continuum, ranging from early onset congenital lactic acidosis to infantile ...
Nandaki Keshavan   +23 more
wiley   +1 more source

Metabolism of vitamin D3 in man [PDF]

open access: yesBiochemical Journal, 1968
E B, Mawer, S W, Stanbury
openaire   +2 more sources

Vitamin D Supplementation and Mortality in the Elderly: A Review of a Meta‐Analysis of Randomized Controlled Trials Using the REB Method

open access: yesFundamental &Clinical Pharmacology, Volume 40, Issue 6, November 2026.
ABSTRACT Background The results of randomized controlled trials (RCTs) regarding the effect of vitamin D supplementation on mortality reduction are conflicting. Objective The aim of this study was to assess the level of evidence through a sensitivity analysis of the meta‐analysis by Shah et al.
Natalia Kostakis   +2 more
wiley   +1 more source

Dose-dependent vitamin D3 supplementation attenuates endothelial dysfunction and renal injury in an obstructive sleep apnea rat model. [PDF]

open access: yesFront Pharmacol
Alotaibi AA   +9 more
europepmc   +1 more source

Systematic Optimization of an SLE‐DAPTAD LC–MS/MS Workflow for Simultaneous Quantification of Low‐Abundance Vitamin D3 Metabolites in Plasma

open access: yesRapid Communications in Mass Spectrometry, Volume 40, Issue 20, 30 October 2026.
ABSTRACT Rationale Liquid chromatography–tandem mass spectrometry (LC–MS/MS) analysis of vitamin D3 metabolites is analytically challenging because these compounds are structurally similar, strongly matrix‐associated, and have poor ionization efficiency.
Marzieh Amirmostofian   +3 more
wiley   +1 more source

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