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Urinary metabolites of vitamin D3
Journal of Steroid Biochemistry, 1980Abstract Relatively little is known regarding the identity of the terminal metabolites of vitamin D 3 , yet measurement of these compounds would give additional useful data on the normal and pathophysioogy of vitamin D in man. We have therefore investigated the metabolism of [26.27- 3 H]-25-hydroxy vitamin D 3 administered orally to a human subject.
C H, Shackleton, E, Roitman, J, Whitney
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Questions on the Use of Vitamin D3
Pediatrics, 1980From their observations in a boy with hypophosphatemic rickets Chan and Bartter1 conclude that administration of 1α,25-dihydroxyvitamin D3 (1,25-(OH)2D3) is the treatment of choice for this disease. Since this point of view is not shared by everybody, it demands careful scrutiny.
S, Balsan, R, Steendijk
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Treatment of osteoporosis with vitamin D3
Osteoporosis International, 1993The aims of the treatment of osteoporosis are to halt the rapid decrease in bone mass, and if possible, to increase the bone mass. Appropriate treatment is expected to lower the incidence of bone fracture in patients with a low bone mass by maintaining or increasing bone mass on a long-term basis.
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Canadian journal of comparative medicine : Revue canadienne de medecine comparee, 1984
Plasma levels of vitamin D3 or 25-hydroxyvitamin D3 in ewes after administration of a single massive intravenous dose of vitamin D3 (2 X 10(6) IU) or 25-hydroxy vitamin D3 (5 mg) were determined at zero, one, two, three, five, ten and 20 days postinjection.
M, Hidiroglou, J E, Knipfel
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Plasma levels of vitamin D3 or 25-hydroxyvitamin D3 in ewes after administration of a single massive intravenous dose of vitamin D3 (2 X 10(6) IU) or 25-hydroxy vitamin D3 (5 mg) were determined at zero, one, two, three, five, ten and 20 days postinjection.
M, Hidiroglou, J E, Knipfel
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La Revue de medecine interne, 2008
Nearly one billion people around the world are deficient in vitamin D and need to be supplemented. Vitamin D is available in medicines and fortified foods. It is available in two forms: vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol).The pharmacopeiae consider these steroid hormones as equivalent and interchangeable.
V I, Mistretta +4 more
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Nearly one billion people around the world are deficient in vitamin D and need to be supplemented. Vitamin D is available in medicines and fortified foods. It is available in two forms: vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol).The pharmacopeiae consider these steroid hormones as equivalent and interchangeable.
V I, Mistretta +4 more
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Steroids, 2015
Information regarding the endogenous storages of vitamin D3 after cutaneous vitamin D synthesis compared to oral vitamin D3 supplementation is sparse. Furthermore it is not known whether vitamin D3 can be stored for later use during periods of shortages of vitamin D3.
Anders, Burild +3 more
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Information regarding the endogenous storages of vitamin D3 after cutaneous vitamin D synthesis compared to oral vitamin D3 supplementation is sparse. Furthermore it is not known whether vitamin D3 can be stored for later use during periods of shortages of vitamin D3.
Anders, Burild +3 more
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Archives of Dermatological Research, 1992
The physiologically active metabolite of vitamin D3, 1 alpha,25-dihydroxycolicalciferol [1,25(OH)2D3, calcitriol] has achieved the status of a hormone. It is believed to mediate its effects by binding to a specific receptor which belongs to the family of nuclear receptors for glucocorticoids, estrogens, thyroxine, and retinoid acid.
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The physiologically active metabolite of vitamin D3, 1 alpha,25-dihydroxycolicalciferol [1,25(OH)2D3, calcitriol] has achieved the status of a hormone. It is believed to mediate its effects by binding to a specific receptor which belongs to the family of nuclear receptors for glucocorticoids, estrogens, thyroxine, and retinoid acid.
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Hepatic accumulation of vitamin D3 and 25-hydroxyvitamin D3☆
Biochimica et Biophysica Acta (BBA) - General Subjects, 1976Concomitant intravenous administration of 25-hydroxycholecalciferol and [3H] vitamin D3 to vitamin D-depleted rats did not affect the conversion of [3H] vitamin D3 to 25-OH-[3H] vitamin D3 as indicated by a serum 25-OH-[3H] vitamin D3 to content at 3 and 24 h identical to those observed in animals receiving [3H] vitamin D3 alone.
S, Rojanasathit, J G, Haddad
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Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 1999
Pharmacokinetic and pharmacodynamic properties of vitamin D3 were described. Clinical aspects of application were also revealed.
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Pharmacokinetic and pharmacodynamic properties of vitamin D3 were described. Clinical aspects of application were also revealed.
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Combined Use of Vitamin D3, Vitamin D3 Metabolites and Vitamin C in Bone Metabolism
1987Vitamin D is formed in the skin or ingested in food and is metabolized in particular organs. It is hydroxylated in the liver by an endoplasmic enzyme to 25(OH)D3. Enzymatic hydroxylation to l,25(OH)2D3 takes place mainly in the mitochondrial portion of the renal cortical cells.
H. Weiser, M. Schlachter
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