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Chromatographic separation of vitamin D3 sulfate and vitamin D3
Steroids, 1978This paper describes a simple chromatographic technique on Sephadex LH20 for the separation of vitamin D3 sulfate from free vitamin D3 and its metabolites. This technique has been used in the study of vitamin D3 sulfate metabolism in rats. Seven hours after injection of vitamin D3 sulfate (35S or 35S and 3H) only the peak of vitamin D sulfoconjugate ...
Y, Sorgue, L, Miravet
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Vitamin d3 and brain development
Neuroscience, 2003Evidence for the presence of the vitamin D receptor in brain implies this vitamin may have some function in this organ. This study investigates whether vitamin D(3) acts during brain development. We demonstrate that rats born to vitamin D(3)-deficient mothers had profound alterations in the brain at birth.
Eyles, D +4 more
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Nihon rinsho. Japanese journal of clinical medicine, 1993
With the application of biochemical technique came the discovery that vitamin D is metabolized sequentially to 25-hydroxyvitamin D in liver and then to 1.25-dihydroxyvitamin D (1.25D), the hormonal form of vitamin D, in kidney. The latter process is strictly controlled with the demand of calcium and phosphorus.
M, Inaba, H, Morii
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With the application of biochemical technique came the discovery that vitamin D is metabolized sequentially to 25-hydroxyvitamin D in liver and then to 1.25-dihydroxyvitamin D (1.25D), the hormonal form of vitamin D, in kidney. The latter process is strictly controlled with the demand of calcium and phosphorus.
M, Inaba, H, Morii
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Molecular and Cellular Endocrinology, 2002
Plasma concentrations of the main vitamin D(3) metabolites (i.e., 25(OH)D(3), 1,25(OH)(2)D(3), and 24,25(OH)(2)D(3)) were measured in 14 weeks old large- and small-breed dogs (adult body weight 60 kg vs. 6 kg), raised under the same conditions. Levels of 25(OH)D(3) (approx. 22 microg/l) and 1,25(OH)(2)D(3) (approx. 40 ng/l) were similar in both groups,
Hazewinkel, H.A.W., Tryfonidou, M.A.
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Plasma concentrations of the main vitamin D(3) metabolites (i.e., 25(OH)D(3), 1,25(OH)(2)D(3), and 24,25(OH)(2)D(3)) were measured in 14 weeks old large- and small-breed dogs (adult body weight 60 kg vs. 6 kg), raised under the same conditions. Levels of 25(OH)D(3) (approx. 22 microg/l) and 1,25(OH)(2)D(3) (approx. 40 ng/l) were similar in both groups,
Hazewinkel, H.A.W., Tryfonidou, M.A.
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Critical Reviews in Eukaryotic Gene Expression, 1998
The physiologically active form of vitamin D3, 1 alpha,25-dihydroxyvitamin D3 (VD), is a nuclear hormone with pleiotropic action on the control of calcium homeostasis and bone formation, induction of cellular differentiation and apoptosis, inhibition of cellular proliferation, and other cellular signaling processes.
C, Carlberg, P, Polly
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The physiologically active form of vitamin D3, 1 alpha,25-dihydroxyvitamin D3 (VD), is a nuclear hormone with pleiotropic action on the control of calcium homeostasis and bone formation, induction of cellular differentiation and apoptosis, inhibition of cellular proliferation, and other cellular signaling processes.
C, Carlberg, P, Polly
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Vitamin D3 and Vitamin D3 Analogues as an Adjunct to Cancer Chemotherapy and Radiotherapy
Current Medicinal Chemistry-Anti-Cancer Agents, 2002The development of drugs that are highly selective and yet produce minimal toxicity to host tissue remains one of the most difficult challenges in cancer therapeutics. Since the majority of malignancies are treated with drugs in combination rather than single agents, one practical approach to circumvent this problem is to develop new therapeutic agents
David A, Gewirtz +2 more
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2016
Most tissue types carry receptors for the vitamin D3 hormone and are therefore receptive to its myriad control signals. It exercises a regulatory function over the activity of at least 200 genes. One important responsibility of this hormone lies in bone metabolism (Chapter 75) and in optimizing the body’s neuromuscular coordination.
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Most tissue types carry receptors for the vitamin D3 hormone and are therefore receptive to its myriad control signals. It exercises a regulatory function over the activity of at least 200 genes. One important responsibility of this hormone lies in bone metabolism (Chapter 75) and in optimizing the body’s neuromuscular coordination.
openaire +1 more source