Results 201 to 210 of about 65,773 (256)
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Vitamin d3 and brain development
Neuroscience, 2003Evidence for the presence of the vitamin D receptor in brain implies this vitamin may have some function in this organ. This study investigates whether vitamin D(3) acts during brain development. We demonstrate that rats born to vitamin D(3)-deficient mothers had profound alterations in the brain at birth.
Eyles, D +4 more
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Nihon rinsho. Japanese journal of clinical medicine, 1993
With the application of biochemical technique came the discovery that vitamin D is metabolized sequentially to 25-hydroxyvitamin D in liver and then to 1.25-dihydroxyvitamin D (1.25D), the hormonal form of vitamin D, in kidney. The latter process is strictly controlled with the demand of calcium and phosphorus.
M, Inaba, H, Morii
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With the application of biochemical technique came the discovery that vitamin D is metabolized sequentially to 25-hydroxyvitamin D in liver and then to 1.25-dihydroxyvitamin D (1.25D), the hormonal form of vitamin D, in kidney. The latter process is strictly controlled with the demand of calcium and phosphorus.
M, Inaba, H, Morii
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Vitamin D3 and calcidiol are not equipotent
The Journal of Steroid Biochemistry and Molecular Biology, 2016Despite the discussion on the optimal threshold of 25-hydroxyvitamin D serum level continues, there is now consensus on the fact that post-menopausal and elderly populations have inadequate Vitamin D serum levels worldwide. The adjustment of these levels is necessary to improve both bone and general health, as it is to optimize bone response to ...
Navarro-Valverde, Cristina +3 more
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2016
Most tissue types carry receptors for the vitamin D3 hormone and are therefore receptive to its myriad control signals. It exercises a regulatory function over the activity of at least 200 genes. One important responsibility of this hormone lies in bone metabolism (Chapter 75) and in optimizing the body’s neuromuscular coordination.
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Most tissue types carry receptors for the vitamin D3 hormone and are therefore receptive to its myriad control signals. It exercises a regulatory function over the activity of at least 200 genes. One important responsibility of this hormone lies in bone metabolism (Chapter 75) and in optimizing the body’s neuromuscular coordination.
openaire +1 more source
Molecular and Cellular Endocrinology, 2002
Plasma concentrations of the main vitamin D(3) metabolites (i.e., 25(OH)D(3), 1,25(OH)(2)D(3), and 24,25(OH)(2)D(3)) were measured in 14 weeks old large- and small-breed dogs (adult body weight 60 kg vs. 6 kg), raised under the same conditions. Levels of 25(OH)D(3) (approx. 22 microg/l) and 1,25(OH)(2)D(3) (approx. 40 ng/l) were similar in both groups,
Hazewinkel, H.A.W., Tryfonidou, M.A.
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Plasma concentrations of the main vitamin D(3) metabolites (i.e., 25(OH)D(3), 1,25(OH)(2)D(3), and 24,25(OH)(2)D(3)) were measured in 14 weeks old large- and small-breed dogs (adult body weight 60 kg vs. 6 kg), raised under the same conditions. Levels of 25(OH)D(3) (approx. 22 microg/l) and 1,25(OH)(2)D(3) (approx. 40 ng/l) were similar in both groups,
Hazewinkel, H.A.W., Tryfonidou, M.A.
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Critical Reviews in Eukaryotic Gene Expression, 1998
The physiologically active form of vitamin D3, 1 alpha,25-dihydroxyvitamin D3 (VD), is a nuclear hormone with pleiotropic action on the control of calcium homeostasis and bone formation, induction of cellular differentiation and apoptosis, inhibition of cellular proliferation, and other cellular signaling processes.
C, Carlberg, P, Polly
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The physiologically active form of vitamin D3, 1 alpha,25-dihydroxyvitamin D3 (VD), is a nuclear hormone with pleiotropic action on the control of calcium homeostasis and bone formation, induction of cellular differentiation and apoptosis, inhibition of cellular proliferation, and other cellular signaling processes.
C, Carlberg, P, Polly
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Vitamin D3 and Vitamin D3 Analogues as an Adjunct to Cancer Chemotherapy and Radiotherapy
Current Medicinal Chemistry-Anti-Cancer Agents, 2002The development of drugs that are highly selective and yet produce minimal toxicity to host tissue remains one of the most difficult challenges in cancer therapeutics. Since the majority of malignancies are treated with drugs in combination rather than single agents, one practical approach to circumvent this problem is to develop new therapeutic agents
David A, Gewirtz +2 more
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Urinary metabolites of vitamin D3
Journal of Steroid Biochemistry, 1980Abstract Relatively little is known regarding the identity of the terminal metabolites of vitamin D 3 , yet measurement of these compounds would give additional useful data on the normal and pathophysioogy of vitamin D in man. We have therefore investigated the metabolism of [26.27- 3 H]-25-hydroxy vitamin D 3 administered orally to a human subject.
C H, Shackleton, E, Roitman, J, Whitney
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Questions on the Use of Vitamin D3
Pediatrics, 1980From their observations in a boy with hypophosphatemic rickets Chan and Bartter1 conclude that administration of 1α,25-dihydroxyvitamin D3 (1,25-(OH)2D3) is the treatment of choice for this disease. Since this point of view is not shared by everybody, it demands careful scrutiny.
S, Balsan, R, Steendijk
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Treatment of osteoporosis with vitamin D3
Osteoporosis International, 1993The aims of the treatment of osteoporosis are to halt the rapid decrease in bone mass, and if possible, to increase the bone mass. Appropriate treatment is expected to lower the incidence of bone fracture in patients with a low bone mass by maintaining or increasing bone mass on a long-term basis.
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