Results 31 to 40 of about 462,758 (290)

Estimation of the Number Needed to Treat, the Number Needed to be Exposed, and the Exposure Impact Number with Instrumental Variables [PDF]

arXiv, 2023
The Number needed to treat (NNT) is an efficacy index defined as the average number of patients needed to treat to attain one additional treatment benefit. In observational studies, specifically in epidemiology, the adequacy of the populationwise NNT is questionable since the exposed group characteristics may substantially differ from the unexposed. To
arxiv  

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

Molecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang, Haimei Wen, Ying Chen, Jingya Ning, Di Hu, Yujiao Dong, Chenyu Yao, Bo Yuan, Shuanying Yang   +8 more
wiley   +1 more source

A reviewed approach to vitamin D supplementation in pediatric age in Portugal

Portuguese Journal of Pediatrics
Vitamin D deficiency is a well-established cause of rickets in children and has been reported as associated to impacts on other systems and organs. Vitamin D deficiency and insufficiency are pediatric worldwide global health problems.
Carla Rêgo, Gonçalo Cordeiro-Ferreira, Maria J. Lages-Fonseca, Mariana Moura-Relvas, Ricardo Ferreira, Sofia Pinto-da Costa   +5 more
doaj   +1 more source

Vitamin D Deficiency Association with Comorbid Diseases in Palestine: “A Cross-Sectional Observation Study”

International Journal of General Medicine, 2022
Abdallah Damin Abukhalil, Hiba Falana,* Rawan Hamayel,* Fatima Yasser,* Aleen Nasser,* Hani Naseef, Ni’meh Al-Shami, Abdullah Rabba Pharmacy Department, Faculty of Pharmacy, Nursing and Health Professions, Birzeit University, Birzeit ...
Abukhalil AD, Falana H, Hamayel R, Yasser F, Nasser A, Naseef H, Al-Shami N, Rabba A   +7 more
doaj  

Vitamin D deficiency in association with endothelial dysfunction: Implications for patients with COVID-19 [PDF]

Reviews in Cardiovascular Medicine, 2020
There is emerging evidence to suggest that vitamin D deficiency is associated with adverse outcomes in COVID-19 patients. Conversely, vitamin D supplementation protects against an initial alveolar diffuse damage of COVID-19 becoming progressively worse ...
Jun Zhang, Peter A. McCullough, Kristen M. Tecson
doaj   +1 more source

Decreased serum vitamin D level as a prognostic marker in patients with COVID-19 [PDF]

arXiv, 2022
Background: The corona virus disease 2019 (COVID-19) pandemic, which is caused by severe acute respiratory syndrome coronavirus 2, is still localized outbreak and has resulted in a high rate of infection and severe disease in older patients with comorbidities.
arxiv  

The role of tachysterol in vitamin D photosynthesis - A non-adiabatic molecular dynamics study [PDF]

Physical Chemistry Chemical Physics 19 (8), 5763-5777 (2017), 2017
To investigate the role of tachysterol in the photophysical/chemical regulation of vitamin D photosynthesis, we studied its electronic absorption properties and excited state dynamics using time-dependent density functional theory (TDDFT), coupled cluster theory (CC2), and non-adiabatic molecular dynamics.
arxiv   +1 more source

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

Molecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad, Caterina Miro, Annarita Nappi, Francesco Del Giudice, Annunziata Gaetana Cicatiello, Serena Sagliocchi, Lucia Acampora, Federica Restolfer, Melania Murolo, Emery Di Cicco, Federico Capone, Ciro Imbimbo, Monica Dentice, Felice Crocetto   +13 more
wiley   +1 more source

Prevalence of Vitamin D deficiency in treatment-naive individual consecutive cancer patients

Cancer Research, Statistics, and Treatment, 2020
Background: There is a lack of information regarding Vitamin D deficiency in treatment-naive cancer patients. Aim: The aim of this was to study the prevalence of Vitamin D deficiency in cancer patients. Objectives: The objective was to measure the extent
Avinash Pandey, Anjana Singh, Shivkant Singh   +2 more
doaj   +1 more source

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

Molecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu, Fenglin Shen, Yang Liu, Ziqing Zhong, Yongling Chen, Zhiyuan Xia, Cuiju Mo, Hongxiu Yu   +7 more
wiley   +1 more source