Results 51 to 60 of about 338,609 (353)

Phenotyping Healthcare Use 2–3 Decades Before the First Multiple Sclerosis Demyelinating Event

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Phenotype hospital, physician, and emergency department (ED) visits by diagnoses and specialty up to 29 years pre‐multiple sclerosis (MS) onset versus a matched population without MS. Methods We identified people with MS (PwMS) using population‐based administrative data from Ontario, Canada (1991–2020).
Helen Tremlett, Karl Everett, Colleen J. Maxwell, Feng Zhu, Ayesha Asaf, Ping Li, Kyla A. McKay, Yinshan Zhao, Ruth Ann Marrie   +8 more
wiley   +1 more source

Frequency and determinants of vitamin D deficiency among premenopausal and postmenopausal women in Karachi Pakistan

BMC Women's Health, 2021
Background Vitamin D deficiency is becoming a serious public health problem, even in sun-drenched cities like Karachi, Pakistan. We investigated the prevalence of vitamin D deficiency and its association with sociodemographic characteristics ...
Uzma Shamsi, Iqbal Azam, Azra Shamsi, Dua Shamsi, David Callen   +4 more
doaj   +1 more source

Prevalence and Related Risk Factors of Vitamin D Deficiency in Saudi Children with Epilepsy

Children, 2022
Background: Vitamin D has a role in the pathogenesis of many medical disorders, especially those of the central nervous system. It is essential in maintaining the bone health of children.
Reem Al Khalifah, Muddathir H. Hamad, Abrar Hudairi, Lujain K. Al-Sulimani, Doua Al Homyani, Dimah Al Saqabi, Fahad A. Bashiri   +6 more
doaj   +1 more source

25(OH)D Inadequacy Has Different Pathway with VEGF in Increases the Risk of Severe Preeclampsia [PDF]

, 2015
Objectives: To identify in vivo correlation between 25(OH)D and VEGF in severe preeclampsia.Materials and Methods: A case control, cross sectional study of 36 pregnant women which consist of 18 patients with preeclampsia and 18 patients as control with ...
Aditiawarman, A. (Aditiawarman), Damayanti, H. E. (Hanifa)   +1 more
core   +1 more source

BCS1L‐Associated Disease: 5′‐UTR Variant Shifts the Phenotype Towards Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To investigate the consequences of a pathogenic missense variant (c.838C>T; p.L280F) and a 5′‐UTR regulatory variant (c.‐122G>T) in BCS1L on disease pathogenesis and to understand how regulatory variants influence disease severity and clinical presentation.
Rotem Orbach, Nunziata Maio, Russell J. Butterfield, A. Reghan Foley, Sarah Silverstein, Yan Li, Katherine Chao, Tanya J. Lehky, Abigail Potticary, Tracey A. Rouault, Sandra Donkervoort, Carsten G. Bönnemann   +11 more
wiley   +1 more source

Vitamin D in pregnancy: A metabolic outlook

Indian Journal of Endocrinology and Metabolism, 2013
Vitamin D deficiency is a preventable health problem. Vitamin D deficiency among pregnant women is frequent in many populations over the world. Research indicates that adequate vitamin D intake in pregnancy is optimal for maternal, fetal and child health.
Manila Kaushal, Navneet Magon
doaj   +1 more source

D-vitamin es neuropathia. [PDF]

, 2014
Diabetes is a widespread disease and, therefore, studies dealing with diabetes and its complications are very important for public health. Numerous reports link vitamin D deficiency to the increased risk of diabetes mellitus and complications such as ...
Kempler, Miklós Soma, Kempler, Péter, Körei, Anna Erzsébet, Martos, Tímea, Németh, Nóra, Putz, Zsuzsanna, Szabó, Márta, Vági, Orsolya Erzsébet   +7 more
core   +1 more source

Timing and Predictive Value of Clinical Conditions Preceding Multiple Sclerosis in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Multiple sclerosis (MS) patients often experience a higher incidence of clinical conditions before diagnosis, suggesting a prodromal phase. However, their predictive value and temporal trajectories remain underexplored. We investigated these aspects using the large UK Biobank's population‐based cohort, which provided clinical ...
Andrea Nova, Teresa Fazia, Giovanni Di Caprio, Davide Gentilini, Luisa Bernardinelli, Roberto Bergamaschi   +5 more
wiley   +1 more source

Cognitive Resilience in Apolipoprotein ε4 Carrier Women Predicted by Neuron‐Derived Extracellular Vesicles

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Apolipoprotein (APOE) ε4 allele is the strongest genetic risk factor for late‐onset Alzheimer's disease (AD); however, many ε4 carriers remain cognitively intact into old age. Leveraging plasma neuron‐derived extracellular vesicles (NDEVs), we sought to identify biomarkers of cognitive resilience and their interplay with APOE ...
Apostolos Manolopoulos, Maja Mustapic, Carlos Nogueras‐Ortiz, Francheska Delgado‐Peraza, Krishna A. Pucha, Pamela J. Yao, Joseph Blommer, Michael P. Vreones, William York, De' Larrian Knight, Stephen R. Rapp, Aladdin H. Shadyab, JoAnn E. Manson, Ramon Casanova, Robert B. Wallace, Luigi Ferrucci, Susan M. Resnick, Dimitrios Kapogiannis   +17 more
wiley   +1 more source

Severe vitamin D deficiency in 6 Canadian First Nation formula-fed infants [PDF]

, 2013
Background. Rickets was first described in the 17th century and vitamin D deficiency was recognized as the underlying cause in the early 1900s. Despite this long history, vitamin D deficiency remains a significant health concern.
Balasubramanian S, Binet A, Camadoo L, Canadian Paediatric Society, Committee on Use of Dietary Reference Intakes in Nutrition Labeling, David L, Gallo S, Godel JC, Hatun S, Haworth HC, Haworth JC, Johnson DD, Lebrun JB, McCaffree J, Moffatt MK, Namgung R, Orbak Z, Pal BR, Rodd C, Rowe PM, Sachan A, Salama MM, Salle BL, Wagner CL, Ward LM, Weiler HA, Wharton B   +26 more
core   +1 more source