Results 21 to 30 of about 168,717 (262)

Vitamin D Analogue-Specific Recruitment of Vitamin D Receptor Coactivators [PDF]

Journal of Bone and Mineral Research, 2002
Abstract Synthetic ligands for the vitamin D receptor (VDR) are potential therapeutic agents for metabolic, neoplastic, and autoimmune disorders. Some of these ligands have similar or more potent antiproliferative, yet reduced hypercalcemic actions, than calcitriol.
Issa, L. L., Leong, G. M., Sutherland, R. L., Eisman, J. A.   +3 more
openaire   +3 more sources

Role of the placental Vitamin D receptor in modulating feto-placental growth in Fetal growth restriction and Preeclampsia-affected pregnancies.

Frontiers in Physiology, 2016
Fetal growth restriction (FGR) is a common pregnancy complication that affects up to 5% of pregnancies worldwide. Recent studies demonstrate that Vitamin D deficiency is implicated in reduced fetal growth, which may be rescued by supplementation of ...
Padma eMurthi, Padma eMurthi, Padma eMurthi, Padma eMurthi, Hannah EJ Yong, Hannah EJ Yong, Thy PH Nguyen, Thy PH Nguyen, Stacey eEllery, Stacey eEllery, Harmeet eSingh, Harmeet eSingh, Rahana eRahman, Rahana eRahman, Hayley eDickinson, Hayley eDickinson, David W Walker, David W Walker, Miranda eDavies-Tuck, Miranda eDavies-Tuck, Euan eWallace, Euan eWallace, Peter eEbeling   +22 more
doaj   +1 more source

Renal vitamin D receptor expression and vitamin D renoprotection [PDF]

Kidney International, 2012
Therapy to enhance the renoprotective actions of vitamin D receptor (VDR) activation should safely overcome the distinct VDR content along the nephron to effectively control renal calcium reabsorption, control renal klotho levels for the phosphaturic actions of FGF23, and inhibit proteinuria and the activation of the renin-angiotensin system.
openaire   +2 more sources

Vitamin D receptor expression levels determine the severity and complexity of disease progression among leprosy reaction patients

New Microbes and New Infections, 2015
We studied the roles of vitamin D and its receptor, VDR, in the progression of leprosy. The majority of individuals with leprosy from Kolkata, India, with a type 1 or type 2 reaction have low levels of vitamin D3 in serum samples.
D. Mandal, A.H.H. Reja, N. Biswas, P. Bhattacharyya, P.K. Patra, B. Bhattacharya   +5 more
doaj   +1 more source

The role of vitamin D in children with recurrent Tonsillopharyngitis

Italian Journal of Pediatrics, 2012
Background The exact etiology of recurrent tonsillopharyngitis in children is not clear. Recurrent tonsillitis in children has multifactorial etiology like most of the diseases in childhood.
Yildiz Ismail, Unuvar Emin, Zeybek Umit, Toptas Bahar, Cacina Canan, Toprak Sadık, Kilic Ayse, Aydin Salih   +7 more
doaj   +1 more source

The pleiomorphic actions of vitamin D and its importance for children [PDF]

Annals of Pediatric Endocrinology & Metabolism, 2013
Knowledge regarding the physiological role and dietary requirements of vitamin D has dramatically expanded over the past several decades. The "new" vitamin D is not only a mediator of calcium homeostasis, it also has important immunomodulatory ...
Se Young Kim
doaj   +1 more source

Vitamin D Signaling in Inflammation and Cancer: Molecular Mechanisms and Therapeutic Implications

Molecules, 2020
Vitamin D and its active metabolites are important nutrients for human skeletal health. UV irradiation of skin converts 7-dehydrocholesterol into vitamin D3, which metabolized in the liver and kidneys into its active form, 1α,25-dihydroxyvitamin D3 ...
Ahmed El-Sharkawy, Ahmed Malki
doaj   +1 more source

Vitamin D and vitamin D receptor in patients with ophthalmic pterygium

European Journal of Histochemistry, 2017
Pterygium, an ultraviolet radiation (UV)-related disease, is a relatively benign process, but since it displays tumor-like features, it has been proposed to be a neoplastic- like growth disorder.
Cristina Maxia, Daniela Murtas, Michela Corrias, Ignazio Zucca, Luigi Minerba, Franca Piras, Cristiana Marinelli, Maria Teresa Perra   +7 more
doaj   +1 more source

Association of vitamin D level and vitamin D receptor A-1012G polymorphism with psoriasis – case control study

Acta Biochimica Indonesiana, 2020
Background: Psoriasis is a chronic inflammation of the skin caused by combination of genetic, immune and environmental factors. The Vitamin D receptors alongside with plasma vitamin D (25(OH)D) level have known to be related with psoriasis.
Pocut Astari, Yahwardiah Siregar, Ariyati Yosi   +2 more
doaj   +1 more source

Lack of vitamin D signalling per se does not aggravate cardiac functional impairment induced by myocardial infarction in mice.

PLoS ONE, 2018
Epidemiological studies have linked vitamin D deficiency to an increased incidence of myocardial infarction and support a role for vitamin D signalling in the pathophysiology of myocardial infarction.
Kristopher Ford, Nejla Latic, Svetlana Slavic, Ute Zeitz, Marlies Dolezal, Oleh Andrukhov, Reinhold G Erben, Olena Andrukhova   +7 more
doaj   +1 more source