Results 181 to 190 of about 569,165 (382)
ATF3 Deficiency Exacerbates Ageing‐Induced Atherosclerosis and Clinical Intervention Strategy
Advanced Science, EarlyView.Targeting ATF3 with terazosin to against VSMC Senescence and atherosclerosis. TZ reduces the binding affinity of YTHDF2 to Atf3 mRNA, while enhancing mRNA stability. ATF3 promotes Atg7 transcription, enhancing autophagy. ATG7 binds to ATF3 in the cytoplasm, facilitating ATF3 translocation to the nucleus and establishing positive feedback. By modulating
Hao Nie +11 more
wiley +1 more source
Vitamin E deficiency dysregulates thiols, amino acids and related molecules during zebrafish embryogenesis. [PDF]
Redox Biol, 2021 Zhang J +5 more
europepmc +1 more source
CREATINE AND GLYCOCYAMINE METABOLISM IN RABBITS IN VITAMIN E DEFICIENCY
, 1951 Robert S. Melville, J.P. Hummel
openalex +1 more source
Mitochondrial Regulation of CD8⁺ T Cells: Mechanisms and Therapeutic Modulation
Advanced Science, EarlyView.This article comprehensively explores the pivotal role of mitochondrial function in CD8⁺ T cell immunotherapy. It highlights how mitochondrial dynamics regulate T cell activation, differentiation, and persistence, and how mitochondrial dysfunction leads to immune exhaustion and impaired antitumor/antiviral responses.
Xu Chen +7 more
wiley +1 more source
Cot deaths and deficiency of vitamin E and selenium. [PDF]
, 1971 D.F.L. Money
openalex +1 more source
Advanced Science, EarlyView.This study develops a human engineered heart tissue‐derived model of diabetic cardiomyopathy that accurately replicates the dynamic changes in the structural, contractile, and electrophysiological properties of the myocardium. Furthermore, this model is used to confirm the direct protective effects of empagliflozin on the heart through an SGLT2 off ...
Lin Cai +9 more
wiley +1 more source
Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2016 Introduction: Epilepsy is regarded as one of the prevalent neurological disorders in children. The role of anti-oxidants in protection of epilepsy has been discussed in several studies.
S Rezaei Tireh Shabankareh +6 more
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Effect of vitamin C and vitamin E deficiencies upon nitrogen constituents of muscle tissue
, 1951 Marion Barclay
openalex +2 more sources
Advanced Science, EarlyView.This study deciphers maternal‐driven microbial transmission in pigs using a deep learning model (maternal–offspring microbial transmission model), identifying Christensenellaceae R‐7 group as a key transmitted taxon. Filtered galacto‐oligosaccharides‐targeted Christensenellaceae R‐7 group alters offspring microbial functions via maternal ...
Haibo Shen +9 more
wiley +1 more source
Ataxia with vitamin E deficiency associated with deafness
The Turkish Journal of Pediatrics, 2008 Ataxia with vitamin E deficiency (AVED) is a rare autosomal recessive disorder, usually with a phenotype resembling Friedreich ataxia, caused by selective impairment of gastrointestinal vitamin E absorption.
Bülent Kara +6 more
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