Results 261 to 270 of about 569,165 (382)

Advances on Albumin‐Based Carriers for Anticancer Drug Delivery

open access: yesAdvanced NanoBiomed Research, EarlyView.
This study systematically classifies the drug delivery modes of albumin by examining the characteristics of its surface‐active groups and internal binding sites. It provides an in‐depth analysis of various drug delivery strategies and their corresponding targeting mechanisms.
Ruoli Zhou   +4 more
wiley   +1 more source

Exosomes in Intervertebral Disc Regeneration: Roles, Opportunities, and Challenges

open access: yesAdvanced NanoBiomed Research, EarlyView.
Factors of Intervertebral Disc Degeneration Extracellular Matrix (ECM) Exosomes and Intervertebral Disc Degeneration (IVDD) Exosome‐Mediated Therapy for IVDD of Different Cell Sources Application of Engineered Exosomes in IVDD Clinical Application of Exosomes in IVDD Treatment Conclusion and Future Perspectives. Intervertebral disc degeneration (IVDD),
Xianglong Zhou   +7 more
wiley   +1 more source

Neuroleukemiosis Masquerading as Drug Toxicity in an Adolescent With Refractory AML

open access: yes
American Journal of Hematology, EarlyView.
Nia Choi   +11 more
wiley   +1 more source

Stability and Release Characteristics of Core‐Shell Beads with Emulsion Core Under Gastrointestinal Conditions

open access: yesAdvanced NanoBiomed Research, EarlyView.
A combined emulsion–core‐shell structure system is developed for targeted delivery of lipophilic compounds to the proximal intestine. Using vitamin D3‐loaded sunflower oil emulsions, the core‐shell structure enhances droplet stability, encapsulation efficiency, and gastric protection.
Fariba Malekpour Galogahi   +3 more
wiley   +1 more source

Mechanochemical Strategies Applied to the Late‐Stage Modifications of Pharmaceutically Active Compounds

open access: yesAngewandte Chemie International Edition, Accepted Article.
This review explores the potential of mechanochemistry in the late‐stage modification of active pharmaceutical ingredients (APIs), offering a comprehensive analysis of methods designed to transform structurally complex molecular scaffolds. By examining the scope, efficiency, and mechanistic aspects of these approaches, the review highlights protocols ...
Johanna Templ, Lars Borchardt
wiley   +1 more source

Developing HaloTag and SNAP‐Tag Chemical Inducers of Dimerization to Probe Receptor Oligomerization and Downstream Signaling

open access: yesAngewandte Chemie International Edition, EarlyView.
Controlling protein interactions is key to studying signaling. Antibody methods have limits, but chemical inducers of dimerization (CIDs) using HaloTags and SNAP‐Tags offer precise control. We present CIDs to covalently link heteromers with varied linkers and a FRET‐based sensor.
Michael Trumpp   +8 more
wiley   +1 more source

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