Results 291 to 300 of about 512,688 (367)

Flux Sampling Suggests Metabolic Signatures of High Antibody‐Producing CHO Cells

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Chinese hamster ovary (CHO) cells remain the industry standard for producing numerous therapeutic proteins, particularly monoclonal antibodies (mAbs). However, achieving higher recombinant protein titers remains an ongoing challenge and a fundamental understanding of the cellular mechanism driving improved bioprocess performance remains ...
Kate E. Meeson   +9 more
wiley   +1 more source

Physiology and Robustness of Yeasts Exposed to Dynamic pH and Glucose Environments

open access: yesBiotechnology and Bioengineering, EarlyView.
The authors investigated how three Saccharomyces cerevisiae strains respond to dynamic substrate and pH oscillations using dynamic microfluidic single‐cell cultivation (dMSCC) and intracellular biosensors. By combining performance and robustness analysis of selected intracellular parameters, growth and morphological analysis, the authors identified ...
Luca Torello Pianale   +3 more
wiley   +1 more source

Effects of vitamin D supplementation on symptoms and clinical outcomes in adults with different baseline vitamin D levels: an interventional study. [PDF]

open access: yesJ Health Popul Nutr
Albasheer O   +14 more
europepmc   +1 more source

Detecting Excess Biofilm Thickness in Microbial Electrolysis Cells by Real‐Time In‐Situ Biofilm Monitoring

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Long‐term stable operation of bioelectrochemical systems (BES) presupposes the avoidance of mass transfer limitations of the electroactive biofilm. Excessive pH‐gradients from bulk to electrode interface or substrate limitations of the electroactive biofilm are known to diminish the electrical performance of BES.
Andreas Netsch   +3 more
wiley   +1 more source

Deficiency of B vitamins in women of childbearing age, pregnant, and lactating women in Brazil: a systematic review. [PDF]

open access: yesSyst Rev
de Macedo TSG   +6 more
europepmc   +1 more source

Recent advances of nanomaterials in imaging liver fibrosis

open access: yesBMEMat, EarlyView.
Schematic summary on the latest strategies of liver fibrosis imaging based on various nanomaterials. Abstract Liver fibrosis is a pathological process resulting from prolonged exposure to various injury factors. It is characterized by the abnormal proliferation and activation of hepatic stellate cells and excessive deposition of extracellular matrix ...
Jin Cui   +11 more
wiley   +1 more source

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