Results 61 to 70 of about 777,101 (273)

High-levelexpression of functional recombinant human coagulation factor VII in insect cells [PDF]

: Recombinant coagulation factor VII (FVII) is used as a potential therapeutic intervention in hemophilia patients who produce antibodies against the coagulation factors.
AD Shapiro, Ali Jahanian Najafabadi, Amaneh Mohammadi Roushandeh, B Brenner, B Furie, BG Maick, CR Hay, DA Roth, DE Lynn, DR O’Reilly, G Bray, G Kemball-Cook, HJ Cha, I Nillson, KR Kim, Mahdi Edalati Fathabad, Mahdi Rouhbakhsh, Mahshid Mohammadipour, Mehryar Habibi Roudkenar, MK Miller, Mohamad Ali Shokrgozar, Mohamad Salimi, N Wajih, Nasser Masroori, R Halabian, R Toso, Raheleh Halabian, SM Ruiz, SM Wu, T Li, UK Laemmli   +30 more
core   +1 more source

Neuropsychiatric Symptoms Mimicking Dementia in a Patient Treated With Imatinib

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Tyrosine kinase inhibitors are the cornerstone of chronic myeloid leukemia treatment. Newer agents have more potency and a broader spectrum of action, but also a higher potential for neuropsychiatric side effects. We present a case of a patient on imatinib who developed progressive cognitive, mood, and behavioral alterations.
Ashley Jones, Samuele Bonomi, Keith E. Stockerl‐Goldstein, Randall J. Bateman   +3 more
wiley   +1 more source

Quality of anticoagulation with vitamin K antagonists [PDF]

, 2015
[Abstract] Background. Vitamin K antagonists (VKA) have a narrow therapeutic range, and literature analysis reveals poor quality of anticoagulation control.
Francisco Marin, Inmaculada Roldán, Javier Muñiz, Jesús Castillo-Castillo, José Moreno-Arribas, Juan Sanchis, Manuel Anguita, null null, Vicente Bertomeu-González, Vicente Bertomeu-Martínez, Ángel Cequier   +10 more
core   +2 more sources

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

Evaluation and comparison of vitamin profiles of selected traditional rice and yams grown in Sri Lanka

Tropical Agricultural Research, 2019
The current study was designed to evaluate and compare the vitamin composition of selected traditional and improved rice varieties and four Dioscorea spp. commonly grown and consumed in Sri Lanka.
W. M. A. A. Kulasinghe, S. Wimalasiri, G. Samarasinghe, R. Silva, T. Madhujith   +4 more
doaj   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Vitamin k intake and plasma desphospho-uncarboxylated matrix Gla-protein levels in kidney transplant recipients.

PLoS ONE, 2012
Vitamin K is essential for activation of γ-carboxyglutamate (Gla)-proteins including the vascular calcification inhibitor matrix Gla-protein (MGP).
Paul Y Boxma, Else van den Berg, Johanna M Geleijnse, Gozewijn D Laverman, Leon J Schurgers, Cees Vermeer, Ido P Kema, Frits A Muskiet, Gerjan Navis, Stephan J L Bakker, Martin H de Borst   +10 more
doaj   +1 more source

New oral anticoagulants and their reversal agents [PDF]

, 2018
Atrial fibrillation is a commonly encountered pathology in medical practice, and its prevalence has shown a continuous rise over the past years. Atrial fibrillation has a significant impact on patients\u27 quality of life, not only due to the standard ...
Bodean, Oana, Diaconu, Camelia C, Laslo, Crista L, Marcu, Dragos, Neagu, Tiberiu P, Paduraru, Dan N, Pantea Stoian, Anca, Socea, Bogdan, Socea, Laura I, Stanescu, Ana Maria Alexandra   +9 more
core   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Vitamin K prophylaxis in newborns

BMC Pediatrics, 2021
We looked at existing recommendations and supporting evidence on the effectiveness of vitamin K given after birth in preventing the haemorrhagic disease of the newborn (HDN).
Sophie Jullien
doaj   +1 more source