Results 121 to 130 of about 195,506 (167)

Autosomal Recessive Cerebellar Ataxias: Translating Genes to Therapies

Annals of Neurology, EarlyView.
Autosomal recessive cerebellar ataxias are disabling neurodegenerative genetic conditions affecting balance and coordination. Advancements in genomic testing have improved diagnosis, leading to a new focus on the development of targeted precision therapeutics addressing cellular, biochemical, and genetic disease mechanisms with a resulting emphasis on ...
Brent L. Fogel, Thomas Klopstock, David R. Lynch, Francesca Maltecca, Mayank Verma, Berge A. Minassian, Frances M. Platt, Débora Farina Gonçalves, Hélène Puccio, Andreas Roos, Matthis Synofzik   +10 more
wiley   +1 more source

Light‐Triggered CRISPR/Cas12a for Genomic Editing and Tumor Regression

Angewandte Chemie, EarlyView.
A photo‐triggered CRISPR/Cas12a machinery for gene editing is introduced. The machinery is applied for endogenous DNA methyltransferase 1 (DNMT1) gene editing and for in vitro disruption of the hepatocyte growth factor (HGF) gene. The machinery is used for in vivo knockout and disruption of the HGF gene in HepG2 tumors, resulting in effective apoptosis
Hong Liu, Jiantong Dong, Renzhi Wu, Jun Dai, Xiaoding Lou, Fan Xia, Itamar Willner, Fujian Huang   +7 more
wiley   +2 more sources

Nutritional Management for Pediatric Biliary Atresia Patients Preparing for Liver Transplantation. [PDF]

Children (Basel)
Choe U.
europepmc   +1 more source

Thrombocytopenia and Anemia After Cardiac Surgery

American Journal of Hematology, EarlyView.
Myriam Beshai, Nour Alhomsi, Theodore E. Warkentin   +2 more
wiley   +1 more source

Advances on Albumin‐Based Carriers for Anticancer Drug Delivery

Advanced NanoBiomed Research, EarlyView.
This study systematically classifies the drug delivery modes of albumin by examining the characteristics of its surface‐active groups and internal binding sites. It provides an in‐depth analysis of various drug delivery strategies and their corresponding targeting mechanisms.
Ruoli Zhou, Rongbin Zhong, Zhonghui Luo, Hua Wei, Cui‐Yun Yu   +4 more
wiley   +1 more source

Editorial: Synergic combination of natural bioactive compounds for preventing and treating human diseases. [PDF]

Front Nutr
Maisto M, Ben Hsouna A, Tenore GC.
europepmc   +1 more source

Architected Microalgae‐Based Matter via 3D Printing: Properties, Printing Techniques, and Applications

Advanced NanoBiomed Research, EarlyView.
Microalgae are emerging as sustainable and economical bioresources that can be utilized as bioinks for creating constructs with intriguing functionalities. This review discusses the properties and applications of microalgae, providing a comprehensive review of recent advancements and challenges in 3D‐printed microalgae‐based constructs for various ...
Yiwei Zou, Jiuhong Yi, Yunlu Dai, Iek Man Lei   +3 more
wiley   +1 more source

A Hypoxia‐Triggered Bioreduction of Hydrophilic Type I Photosensitizer for Switchable In Vivo Photoacoustic Imaging and High‐Specificity Cancer Phototherapy

Angewandte Chemie, EarlyView.
A hydrophilic type I phototherapeutic agent (NanoPcN8O) was developed which selectively responded to hypoxic tumor microenvironments and switched on type I photodynamic and photothermal effects as well as a photoacoustic signal for activatable photoacoustic imaging and tumor phototherapy.
Yuan‐Yuan Zhao, Yihui Xu, Xiaojun Zhang, Zixuan Chen, Heejeong Kim, Xingshu Li, Juyoung Yoon   +6 more
wiley   +2 more sources

Perfluoroalkyl and Polyfluoroalkyl Substances (PFAS) and Vitamin Metabolism: A Nutritional Perspective on an Emerging Environmental Health Issue. [PDF]

Nutrients
Liu C, Zhou B, Huang L, Han D, He M, Zhou M, Xu P, Zhang R.   +7 more
europepmc   +1 more source

Associations between the intake of single and multiple dietary vitamins and depression risk among populations with chronic kidney disease. [PDF]

Front Nutr
Yu C, Liu K, Yao W, Tang D.
europepmc   +1 more source