Results 111 to 120 of about 57,061 (258)
Drug–drug interaction profile of ritlecitinib as perpetrator and victim through cytochrome P450
British Journal of Clinical Pharmacology, Volume 91, Issue 8, Page 2316-2326, August 2025.Aims To assess the effect of a potent cytochrome P450 (CYP) 3A inhibitor and CYP inducer on the pharmacokinetics of ritlecitinib, a JAK3/TEC family kinase inhibitor, and assess the effect of ritlecitinib on the pharmacokinetics of CYP substrates (midazolam, efavirenz, tolbutamide, caffeine and oral contraceptives [ethinyl oestradiol and levonorgestrel])
Vivek S. Purohit +6 more
wiley +1 more source
Psoriasis and vitiligo are close relatives
Clinical, Cosmetic and Investigational Dermatology, 2017 Khalifa E Sharquie,1 Husam Ali Salman,1 Aseel K Yaseen2 1Department of Dermatology and Venereology, College of Medicine, University of Baghdad, Baghdad, Iraq, 2Department of Dermatology and Venereology, Baghdad Teaching Hospital, Baghdad, Iraq Background:
Sharquie KE, Salman HA, Yaseen AK
doaj
Anais Brasileiros de Dermatologia, 2011 FUNDAMENTO: O vitiligo é considerado a hipomelanose adquirida mais frequente. Apesar de sua etiopatogenia ser incerta, acredita-se que a etiologia autoimune seja a mais plausível, teoria que se fundamenta na concomitância de vitiligo com doenças ...
Daniel Holthausen Nunes +1 more
doaj +1 more source
Clinical Case Reports, Volume 13, Issue 8, August 2025.ABSTRACT Congenital melanocytic nevi (CMN), arising from the proliferation of melanocytes, manifest at birth and are colloquially termed as bathing trunk, coat‐sleeve, or stocking nevi. These lesions, occurring in approximately 1 to 2% of neonates, predominantly localize over the trunk and thigh regions.
Nabaa Al‐Zubaidi +4 more
wiley +1 more source
Categories of Cutaneous Mosaicism
JEADV Clinical Practice, Volume 4, Issue 3, Page 652-658, August 2025.ABSTRACT In this overview, the following 12 different categories of cutaneous mosaicism are considered: (1) Discrimination between monoallelic and biallelic mosaicism in autosomal dominant traits; (2) Segmental versus disseminated mosaicism in autosomal dominant disorders.
Rudolf Happle
wiley +1 more source
Anais Brasileiros de Dermatologia, 2005 FUNDAMENTOS: O estudo da associação de psoríase e vitiligo é necessário em razão das prováveis origens imunológicas dessas enfermidades e da proximidade de loci encontrados no cromossomo 1p31.
Caio César Silva de Castro
doaj +1 more source
Macrophages: Subtypes, Distribution, Polarization, Immunomodulatory Functions, and Therapeutics
MedComm, Volume 6, Issue 8, August 2025.Macrophages originate from the yolk sac, fetal liver, and bone marrow, differentiating into two main subtypes: M1‐like (proinflammatory) and M2‐like (anti‐inflammatory). These subtypes exhibit high plasticity, allowing them to transform in response to environmental cues or therapeutic interventions.
Mengyuan Peng +10 more
wiley +1 more source