Results 91 to 100 of about 389,924 (238)

Molecular and cellular mechanisms underlying gyrate atrophy: Why is the retina primarily affected?

Acta Ophthalmologica, Volume 103, Issue 7, Page e436-e455, November 2025.
Abstract Gyrate atrophy of the choroid and retina (GACR; OMIM #258870) is a rare early‐onset autosomal recessive disorder, caused by bi‐allelic pathogenic variants in the gene coding for ornithine aminotransferase (OAT) resulting in hyperornithinaemia.
Mark J. N. Buijs, Berith M. Balfoort, Marion M. Brands, Anneloor L. M. A. ten Asbroek, Camiel J. F. Boon, Roselie M. H. Diederen, Corrie Timmer, Margreet A. E. M. Wagenmakers, Hans R. Waterham, Ronald J. A. Wanders, Riekelt H. Houtkooper, Clara D. van Karnebeek, Arthur A. Bergen   +12 more
wiley   +1 more source

Intravitreal injection of bevacizumab in primary vitrectomy to decrease the rate of retinal redetachment: A randomized pilot study

Journal of Ophthalmic & Vision Research, 2016
Purpose: To evaluate the effect of intravitreal bevacizumab (IVB) as a surgical adjunct in prevention of proliferative vitreoretinopathy (PVR) after retinal detachment surgery. Methods: In this controlled, randomized pilot study, 27 patients with primary
Adib Tousi, Hossein Hasanpour, Masoud Soheilian   +2 more
doaj   +1 more source

Profound Re-Organization of Cell Surface Proteome in Equine Retinal Pigment Epithelial Cells in Response to In Vitro Culturing [PDF]

, 2012
The purpose of this study was to characterize the cell surface proteome of native compared to cultured equine retinal pigment epithelium (RPE) cells. The RPE plays an essential role in visual function and represents the outer blood-retinal barrier.
Aisenbrey, Alcazar, Alge, Bhutto, Bodaghi, Burke, Campochiaro, Christoph Szober, Chu, Claudia Alge-Priglinger, Clegg, Cornelia Deeg, Deeg, Deeg, Deeg, Deeg, Deeg, Degroote, Doherty, Dunn, Eberhardt, Ehrenhofer, Greer, Gullapalli, Gundersen, Ham, Hamel, Hauck, Hauck, Hauck, Hauck, Ho, Huang, Karl, Kerstin Euler, Kristina Fröhlich, Li, Limb, Machemer, Marius Ueffing, McBee, Milyushina, Mochizuki, Muramatsu, Nagai, Parker, Philp, Rizzolo, Rotilio, Singer, Stefanie Hauck, Strauss, Vacanti, Wolf, Wu   +54 more
core   +3 more sources

Internal closure of a posterior perforation using amniotic membrane: A novel surgical technique

Acta Ophthalmologica, Volume 104, Issue 2, Page 236-238, March 2026.
J. S. Suwandi, B. A. van der Wel, E. H. C. van Dijk, S. S. Manning, M. Manzulli, P. Geeraert, S. van Romunde, K. Faridpooya   +7 more
wiley   +1 more source

Free Radicals in Health and Disease

MedComm, Volume 6, Issue 10, October 2025.
Free radicals have dual roles that can either selectively create oxidative damages to transformed cells in treating proliferative diseases such as cancers and some dermatological disorders or boost the antioxidant system in treating degenerative diseases such as neurodegenerative disorder, joint degeneration, and metabolic conditions.
Xiaofeng Dai, Zizheng Huang, Ruohan Lyu
wiley   +1 more source

Osteoprotegerin is a new regulator of inflammation and angiogenesis in proliferative diabetic retinopathy [PDF]

, 2003
Osteoprotegerin (OPG) is a novel regulator of endothelial cell function, angiogenesis, and vasculogenesis. We correlated expression levels of OPG with those of the angiogenic and inflammatory factors vascular endothelial growth factor (VEGF) and monocyte
Abu El-Asrar, Ahmed M, Struyf, Sofie, Mohammad, Ghulam, Gouwy, Mieke, Rytinx, Pieter, Siddiquei, Mohammad Mairaj, Hernández, Cristina, Alam, Kaiser, Mousa, Ahmed, De Hertogh, Gert, Opdenakker, Ghislain, Simó, Rafael   +11 more
core   +3 more sources

Dual‐Crosslinked Betaine‐Based Amphiphilic Hydrogel as a Promising Vitreous Substitute: Anti‐Adhesion, Anti‐Fouling, and Anti‐Cell Proliferation

Advanced Science, Volume 12, Issue 36, September 25, 2025.
A novel multiple cross‐linked betaine‐type amphiphilic polymer hydrogels are developed via in situ free radical copolymerization. The resultant formation, named P(SBMA‐co‐AANa) hydrogel, functions as a vitreous substitute and demonstrates superior performance in optical properties, support capacity, and biocompatibility on a vitrectomized rabbit model.
Yuting Cai, Yun Tan, Jian Cao, Xiaoyuan Zhou, Xingyuan Li, Jianghua Li, Chuntai Liu, Yi Zhang, Yun Li   +8 more
wiley   +1 more source

CHARACTERISTICS OF RETINAL DETACHMENT PATIENTS WITH PROLIFERATIVE VITREORETINOPATHY AT Dr. SOETOMO GENERAL ACADEMIC HOSPITAL

IJRETINA (International Journal of Retina), 2019
Introduction: The aim of this study is to evaluate the incidence and characteristics of retinal detachment patients with proliferative vitreoretinopathy.
Ifan Romadhon Lukmana, Sauli Ari Widjaja, Wimbo Sasono, Muhammad Firmansjah, Ima Yustiarini, Ady Dwi Prakosa, Moestidjab Moestidjab, Gatut Suhendro   +7 more
doaj   +1 more source

Comparison of treatment routine using aflibercept: Strict vs. relaxed retreatment regimen (TOLERANT study)—A non‐inferiority, randomized controlled trial

Acta Ophthalmologica, Volume 103, Issue 6, Page e385-e393, September 2025.
Abstract Purpose This trial evaluated the noninferiority of a relaxed compared to a strict treat‐and‐extend treatment strategy in patients with neovascular Age‐related macular degeneration (AMD). Methods Multicenter, randomized, controlled, phase IV, non‐inferiority clinical trial.
Damian Jaggi, Lieselotte E. Berger, Sandrine Zweifel, Matthias D. Becker, Stephan Michels, Odile Stalder, Joel‐Benjamin Lincke, Oussama Habra, Sebastian Wolf, Martin S. Zinkernagel   +9 more
wiley   +1 more source

A Retrospective Clinical Study of the Etiology and Post-operative Visual Outcome of Rhegmatogenous Retinal Detachment [PDF]

Journal of Clinical and Diagnostic Research, 2014
Aim: To study the etiology of rhegmatogenous retinal detachment and visual outcome after retinal detachment surgery. Materials and methods: Retrospective study conducted at the tertiary eye care hospital over a period of one year.
Achyut N Pandey, Anil Kakde
doaj   +1 more source