Results 101 to 110 of about 389,924 (238)
Personalized Medicine in Ocular Fibrosis: Myth or Future Biomarkers [PDF]
, 2016 SIGNIFICANCE: Fibrosis-related events play a part in the pathogenesis or failure of treatment of virtually all the blinding diseases around the world, and also account for over 40% of all deaths.
Khaw, PT, Yu-Wai-Man, C
core +1 more source
Post‐Translational Modifications in Cilia and Ciliopathies
Advanced Science, Volume 12, Issue 31, August 21, 2025.This review synthesizes current understanding of post‐translational modifications (PTMs) in ciliary proteins and emphasizes their roles in ciliary formation, homeostasis, and signaling. This review also discusses the implication of PTM dysregulation in ciliopathies and explores therapeutic strategies targeting PTM‐modifying enzymes.
Jie Ran, Jun Zhou
wiley +1 more source
Hybrid wide-angle viewing-endoscopic vitrectomy using a 3D visualization system
Clinical Ophthalmology, 2018 Mihori Kita, Yuki Mori, Sachiyo Hama Department of Ophthalmology, National Organization Kyoto Medical Center, Kyoto, Japan Purpose: To introduce a hybrid wide-angle viewing-endoscopic vitrectomy, which we have reported, using a 3D visualization system ...
Kita M, Mori Y, Hama S
doaj
Therapeutic Interventions against Inflammatory and Angiogenic Mediators in Proliferative Diabetic Retinopathy [PDF]
, 2012 The global prevalence of diabetes is estimated to be 336 million people, with diabetic complications contributing to significant worldwide morbidity and mortality.
Gologorsky, Daniel +2 more
core +3 more sources
Alzheimer's &Dementia, Volume 21, Issue 8, August 2025.Abstract Diabetic retinopathy (DR) and Alzheimer's disease (AD) are progressive neurodegenerative disorders affecting the eye and the brain, respectively. Despite targeting different organs, they share common molecular mechanisms. A central process connecting these conditions is the unfolded protein response (UPR), which maintains protein homeostasis ...
Adrián G. Palacios +2 more
wiley +1 more source
Proliferative vitreoretinopathy: current and emerging treatments
Clinical Ophthalmology, 2012 Ama Sadaka,1 Gian Paolo Giuliari2,31Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, MA, USA; 2Centro de Cirugía Oftalmológica (CECOF), Caracas, Venezuela; 3Department of Ophthalmology, Domingo Luciani ...
Sadaka A, Giuliari GP
doaj
Leveraging AAV1-Rac1T17N to prevent experimental proliferative vitreoretinopathy
Journal of Translational MedicineBackground Platelet-derived growth factor receptor β (PDGFRβ) is the principal PDGFR isoform in retinal pigment epithelial (RPE) cells from the epiretinal membranes of patients with proliferative vitreoretinopathy (PVR).
Duo Li +8 more
doaj +1 more source
Journal of Neurochemistry, Volume 169, Issue 8, August 2025.GABA receptors, widely expressed in the retina, play a key role in lateral inhibition and synaptic regulation. Emerging evidence links their dysregulation to retinal diseases such as diabetic retinopathy, retinitis pigmentosa, glaucoma, and age‐related macular degeneration.
Alan E. Medina Arellano +5 more
wiley +1 more source
Inflammatory and angiogenic protein detection in the human vitreous : cytometric bead assay [PDF]
, 2011 Introduction. To evaluate clinical feasibility and reproducibility of cytometric bead assay (CBA) in nondiluted vitreous samples of patients with age-related macular degeneration (ARMD), diabetic macular edema (DME), and central retinal vein occlusion ...
Koch, Frank H. +2 more
core
Interference microscopy delineates cellular proliferations on flat mounted internal limiting membrane specimens. [PDF]
, 2009 Aim: To demonstrate that interference microscopy of flat mounted internal limiting membrane specimens clearly delineates cellular proliferations at the vitreomacular interface.
Gandorfer, Arnd +4 more
core +1 more source