Results 31 to 40 of about 377,437 (162)

p21CIP/WAF1 saRNA inhibits proliferative vitreoretinopathy in a rabbit model.

PLoS ONE, 2023
PurposeProliferative vitreoretinopathy (PVR) is a disease process resulting from proliferation of retinal pigment epithelial (RPE) cells in the vitreous and periretinal area, leading to periretinal membrane formation and traction and eventually to ...
Qi Zhang, Yangchen Guo, Moorim Kang, Wei-Hsiang Lin, Jian-Cheng Wu, Ying Yu, Long-Cheng Li, Aimin Sang   +7 more
doaj   +2 more sources

Polarity and epithelial-mesenchymal transition of retinal pigment epithelial cells in proliferative vitreoretinopathy

PeerJ, 2020
Under physiological conditions, retinal pigment epithelium (RPE) is a cellular monolayer composed of mitotically quiescent cells. Tight junctions and adherens junctions maintain the polarity of RPE cells, and are required for cellular functions.
Hui Zou, Chenli Shan, Linlin Ma, Jia Liu, Ning Yang, Jinsong Zhao   +5 more
semanticscholar   +1 more source

Exosomes mediate an epithelial‐mesenchymal transition cascade in retinal pigment epithelial cells: Implications for proliferative vitreoretinopathy

Journal of Cellular and Molecular Medicine, 2020
Exosomes have recently emerged as a pivotal mediator of many physiological and pathological processes. However, the role of exosomes in proliferative vitreoretinopathy (PVR) has not been reported.
Yao Zhang, Kaizhe Wang, Jiabin Pan, Shuai Yang, Haipei Yao, Min Li, Hui Li, Hetian Lei, Haiying Jin, F. Wang   +9 more
semanticscholar   +1 more source

Retinal shortening: Ultrasonic evaluation of proliferative vitreoretinopathy

Indian Journal of Ophthalmology, 2017
Purpose: To evaluate the effect of extraretinal proliferative vitreoretinopathy (PVR) on retinal shortening in eyes with rhegmatogenous retinal detachment (RD) using ultrasound (USG) and objectively prove the presence of intraretinal PVR (iPVR). Methods:
Brijesh Takkar, Shreyas Temkar, Nripen Gaur, Pradeep Venkatesh, Rohan Chawla, Atul Kumar   +5 more
doaj   +1 more source

MicroRNAs in the Vitreous Humor of Patients with Retinal Detachment and a Different Grading of Proliferative Vitreoretinopathy: A Pilot Study

Translational Vision Science & Technology, 2020
Purpose Although the expression of microRNAs (miRNAs) in retinal pigment epithelial (RPE) cells undergoing epithelial-mesenchymal transition (EMT) is involved in the pathogenesis of proliferative vitreoretinopathy (PVR), its expression in the vitreous of
M. Toro, M. Reibaldi, T. Avitabile, C. Bucolo, S. Salomone, R. Rejdak, K. Nowomiejska, Sarah Tripodi, C. Posarelli, M. Ragusa, C. Barbagallo   +10 more
semanticscholar   +1 more source

Infectious necrotizing scleritis and proliferative vitreoretinopathy after scleral buckling in a patient with atopic dermatitis

American Journal of Ophthalmology Case Reports, 2021
Purpose: To report a case of necrotizing scleritis and proliferative vitreoretinopathy due to an acute infection following scleral buckling for the management of rhegmatogenous retinal detachment in a patient with untreated atopic dermatitis ...
Hajime Sakata, Yosuke Harada, Tomona Hiyama, Yoshiaki Kiuchi   +3 more
doaj  

Endoscopy-assisted pars plana vitrectomy in retinal detachments associated with anterior proliferative vitreoretinopathy and epiciliary membranes

BMC Ophthalmology, 2023
Background Proliferative vitreoretinopathy (PVR) is the leading cause of recurrent retinal detachment. Anterior PVR can contribute to recurrent retinal detachment and is often difficult to remove during conventional pars plana vitrectomy.
Radwan S. Ajlan, Matthew Pfannenstiel, Yong Kam, Harrison Sciulli   +3 more
doaj   +1 more source

Predictive modeling of proliferative vitreoretinopathy using automated machine learning by ophthalmologists without coding experience

Scientific Reports, 2020
We aimed to assess the feasibility of machine learning (ML) algorithm design to predict proliferative vitreoretinopathy (PVR) by ophthalmologists without coding experience using automated ML (AutoML).
F. Antaki, Ghofril Kahwati, Julia Sebag, R. Coussa, Anthony Fanous, R. Duval, M. Sebag   +6 more
semanticscholar   +1 more source

Topical delivery of a small molecule RUNX1 transcription factor inhibitor for the treatment of proliferative vitreoretinopathy

Scientific Reports, 2020
Proliferative vitreoretinopathy (PVR) is the leading cause of retinal detachment surgery failure. Despite significant advances in vitreoretinal surgery, it still remains without an effective prophylactic or therapeutic medical treatment.
Santiago Delgado-Tirado, Dhanesh Amarnani, Guannan Zhao, E. Rossin, D. Eliott, John B. Miller, Whitney A. Greene, Leslie Ramos, Said Arévalo-Alquichire, David Leyton-Cifuentes, L. González-Buendía, Daniela Isaacs-Bernal, Hannah A. B. Whitmore, N. Chmielewska, Brandon V. Duffy, Eric J. Kim, H. Wang, J. Ruiz-Moreno, L. Kim, Joseph F. Arboleda-Velasquez   +19 more
semanticscholar   +1 more source

Transmission electron microscopy of the vitreous body tissue in chronic hemophthalmos

Veterinární Medicína, 2005
Haemolytic products arising in chronic hemophthalmos cause cellular infiltration, necrosis of the vitreous structure, and fibrous membrane formation. In this process, retinal pigment epithelium plays an important role for its antioxidant properties and ...
S. Synek, L. Pac
doaj   +1 more source