Results 51 to 60 of about 114,620 (205)
iScience, 2020 Summary: Rare diseases are an emerging global health priority. Although individually rare, the prevalence of rare “orphan” diseases is high, affecting approximately 300 million people worldwide.
Gabriel Velez, Vinit B. Mahajan
doaj +1 more source
Immunity, Inflammation and Disease, Volume 14, Issue 6, June 2026.ABSTRACT Objective To systematically review the structural features of secreted frizzled‑related protein 5 (SFRP5) and its dual regulation of canonical/non‑canonical Wnt signaling, analyze its association with metabolic disorders, and specifically explore the role and mechanisms of the SFRP5–lipid metabolism axis in neural and optic nerve development ...
Qianfang Jia +4 more
wiley +1 more source
Molecular Genetics &Genomic Medicine, Volume 14, Issue 6, June 2026.Overview of neurological, ocular, and genetic findings in individuals with bi‐allelic loss‐of‐function (LoF) ESAM variants. All affected subjects (n = 21) exhibited characteristic neurovascular and neurodevelopmental anomalies, while 45% also showed ocular (mainly retinal) involvement.
Mauro Lecca +7 more
wiley +1 more source
Proliferative vitreoretinopathy: an update on the current and emerging treatment options. [PDF]
Proliferative vitreoretinopathy (PVR) remains the main cause of failure in retinal detachment (RD) surgery and a demanding challenge for vitreoretinal surgeons.
Ferro Desideri, Lorenzo +4 more
core +2 more sources
, 2020 A Therapeutic Perspective for Proliferative Vitreoretinopathy Based on the Inhibition of Epithelial-Mesenchymal Transition by miR ...
Decimo, Ilaria +2 more
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The impact of octreotide in experimental proliferative vitreoretinopathy
Indian Journal of Ophthalmology, 2013 Aims: This study aims to investigate the effects of intravitreal octreotide on the growth factors, which have significant roles in the pathogenesis of proliferative vitreoretinopathy (PVR). Settings and Design: An experimental trial.
Ozge Evren +3 more
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Migrasomes, Matrix‐Bound Nanovesicles, and More: Messengers in the Matrix
PROTEOMICS, Volume 26, Issue 6, Page 9-21, June 2026.ABSTRACT Extracellular vesicles (EVs) and particles (EPs) are diverse micro‐ and nanoparticles that circulate in bodily fluids and can attach to, or be deposited onto, the extracellular matrix (ECM) and other surfaces. To date, the nomenclature and classification of matrix‐bound or matrix‐associated EVs and EPs (MEVPs) have been unclear, largely due to
Anna V. Kolesov +3 more
wiley +1 more source
A Retrospective Clinical Study of the Etiology and Post-operative Visual Outcome of Rhegmatogenous Retinal Detachment [PDF]
Journal of Clinical and Diagnostic Research, 2014 Aim: To study the etiology of rhegmatogenous retinal detachment and visual outcome after retinal detachment surgery. Materials and methods: Retrospective study conducted at the tertiary eye care hospital over a period of one year.
Achyut N Pandey, Anil Kakde
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Vitreoretinal complications and surgical outcomes in patients with X‐linked retinoschisis
Acta Ophthalmologica, Volume 104, Issue 4, Page 410-422, June 2026.Abstract Purpose X‐linked retinoschisis (XLRS) is an inherited vitreoretinal disorder characterized by macular retinoschisis. In a subgroup of patients, peripheral retinoschisis can occur, potentially leading to complications such as vitreous haemorrhage (VH) and retinal detachment (RD).
Jonathan Hensman +11 more
wiley +1 more source
Experimental Models to Study Epithelial-Mesenchymal Transition in Proliferative Vitreoretinopathy
, 2023 Proliferative vitreoretinal diseases (PVDs) encompass proliferative vitreoretinopathy (PVR), epiretinal membranes, and proliferative diabetic retinopathy.
François Willermain +5 more
core +1 more source