Results 41 to 50 of about 9,135 (190)

Molecular Surgery: Proteomics of a Rare Genetic Disease Gives Insight into Common Causes of Blindness

open access: yesiScience, 2020
Summary: Rare diseases are an emerging global health priority. Although individually rare, the prevalence of rare “orphan” diseases is high, affecting approximately 300 million people worldwide.
Gabriel Velez, Vinit B. Mahajan
doaj   +1 more source

Proliferative vitreoretinopathy

open access: yesZdravniški Vestnik, 2005
Background: Proliferative vitreoretinopathy (PVR) is a disease characterized by formation of membranes on both surfaces of the retina and vitreous base. PVR is a wound healing response which is inadequate and uncontrolled in the eye. Identifying the risk
Mojca Globočnik-Petrovič   +1 more
doaj  

Annexin A2 promotes proliferative vitreoretinopathy in response to a macrophage inflammatory signal in mice

open access: yesNature Communications
Proliferative vitreoretinopathy is a vision-threatening response to penetrating ocular injury, for which there is no satisfactory treatment. In this disorder, retinal pigment epithelial cells, abandon their attachment to Bruch’s membrane on the scleral ...
Min Luo   +7 more
doaj   +1 more source

Anterior proliferative vitreoretinopathy in a patient with Coats disease [PDF]

open access: yesInternational Journal of Ophthalmology, 2018
Letter to the ...
Satoru Kase   +3 more
doaj   +1 more source

Preoperative electrophysiological characterization of patients with primary macula-involving rhegmatogenous retinal detachment [PDF]

open access: yes, 2018
Purpose: To determine 1) which components of retinal function are impaired after rhegmatogenous retinal detachment, 2) which outer retinal pathways (rod- or cone-driven) are more severely affected, and 3) whether there is concomitant inner retinal ...
Apte, Rajendra   +3 more
core   +3 more sources

Tolerability and Efficacy of Multiple Series of Intravitreal Methotrexate Injections for Complex Retinal Detachment Associated with Proliferative Vitreoretinopathy

open access: yesFuture Pharmacology, 2023
In this study, we retrospectively reviewed the outcomes of patients treated with one or more series of intravitreal methotrexate (MTX) injections as a surgical adjunct for the prevention of recurrent rhegmatogenous retinal detachment (RRD) related to ...
Tessnim R. Ahmad, Jay M. Stewart
doaj   +1 more source

Human cytokines activate JAK–STAT signaling pathway in porcine ocular tissue [PDF]

open access: yes, 2015
Background: The JAK/STAT (Janus Tyrosine Kinase, Signal Transducers and Activators of Transcription) pathway is associated with cytokine or growth factor receptors and it is critical for growth control, developmental regulation and homeostasis.
Barteneva, Natasha S   +8 more
core   +1 more source

Experimental proliferative vitreoretinopathy

open access: yesYeungnam University Journal of Medicine, 1991
The authors performed experimental study to produce proliferative vitreoretinopathy by intravitreal injection of homologous fibroblasts in pigmented rabbits. Twenty four eyes of 12 rabbits were divided into control and experimental groups. In experimental group, the eyes were pretreated with expanding gas, perfluoropropane for the vitrectomy.
Duk Kee Hahn   +2 more
openaire   +2 more sources

Lipid peroxidation in proliferative vitreoretinopathies [PDF]

open access: yesEye, 1999
To study the lipid hydroperoxide activity in vasoproliferative and fibroproliferative retinal disorders.Vitreous body samples from patients undergoing vitrectomy because of proliferative vitreoretinopathy (PVR; n = 12) or proliferative diabetic retinopathy (PDR; n = 15), and rhegmatogenous retinal detachment/macular hole/epiretinal membranes as the ...
P Marco   +3 more
openaire   +3 more sources

The impact of octreotide in experimental proliferative vitreoretinopathy

open access: yesIndian Journal of Ophthalmology, 2013
Aims: This study aims to investigate the effects of intravitreal octreotide on the growth factors, which have significant roles in the pathogenesis of proliferative vitreoretinopathy (PVR). Settings and Design: An experimental trial.
Ozge Evren   +3 more
doaj   +1 more source

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