Results 181 to 190 of about 208,965 (228)
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 46, Issue 11, November 2026.ABSTRACT Introduction Non‐infectious uveitis (NIU) is a chronic immune‐mediated ocular inflammatory disease that may cause irreversible visual impairment. The comparative efficacy and safety of systemic immunomodulatory therapies, including conventional agents and biologics, remain incompletely defined.
Kai‐Yang Chen +2 more
wiley +1 more source
Recombinant versus native botulinum neurotoxin type A: structural and pharmacodynamic comparison
Acta Crystallographica Section F, Volume 82, Issue 11, Page 391-401, November 2026.For the first time, the recombinant core botulinum neurotoxin type A (BoNT/A) expressed in Escherichia coli and nicked in vitro is shown to be structurally identical to native BoNT/A from Clostridium botulinum, enabling direct activity comparison between the recombinant product and the native toxin.Botulinum neurotoxins (BoNTs) are highly potent ...
Zongren Yao +9 more
wiley +1 more source
3dcon: tomogram denoising by deconvolution
Acta Crystallographica Section D, Volume 82, Issue 11, Page 1240-1250, November 2026.An open‐source entropy‐regularized deconvolution workflow is presented for denoising tomographic reconstructions from cryo‐electron microscopy.Cryo‐electron tomography is an expanding technology for the study of macromolecules, viruses and cells.
Peter Kirchweger +3 more
wiley +1 more source
The impacts of high refractive errors on self‐reported visual function and visual concern
Acta Ophthalmologica, Volume 104, Issue 7, Page 780-788, November 2026.Abstract Purpose To examine the association between refractive errors and self‐reported visual function and visual concern, considering self‐perceived present eyesight, concerns about vision, accomplishing less and limitations in daily activities in an eye‐healthy cohort.
Jens Riis Møller +9 more
wiley +1 more source
Acta Ophthalmologica, Volume 104, Issue 7, Page e724-e744, November 2026.Abstract Coats disease diagnosed in adulthood is a rare idiopathic retinal telangiectatic vasculopathy that may differ in phenotype from childhood‐diagnosed cases. This systematic review synthesizes current evidence to characterize its clinical spectrum, imaging features, treatment outcomes and underlying mechanisms, with a focus on immunovascular ...
Catarina Francisco +2 more
wiley +1 more source
Clinical and Experimental Neuroimmunology, Volume 17, Issue 4, November 2026.ABSTRACT Background Paraneoplastic and autoimmune retinopathies can cause progressive visual loss before structural ophthalmic or neurologic findings are diagnostic. Case Presentation A 66‐year‐old woman developed bilateral visual decline and was diagnosed with small‐cell lung cancer‐associated paraneoplastic neuroretinal dysfunction, with persistent ...
Alan B. Dogan +2 more
wiley +1 more source
Ocular Manifestations of Metabolic Syndrome: A Systemic Vascular Phenotype
Diabetes, Obesity and Metabolism, Volume 28, Issue 11, Page 9809-9818, November 2026.ABSTRACT Context Metabolic syndrome (MetS) is defined by central obesity, insulin resistance, hypertension and dyslipidemia. MetS affects over one‐third of US adults. Beyond its cardiovascular burden, MetS has clinically relevant associations with ocular health and may contribute to a systemic vascular and neuro‐metabolic phenotype involving the retina,
Ron T. Varghese, Ansu A. John
wiley +1 more source
Ideal Silicate Glass Compositions: From the Perspective of Network Topology
Journal of the American Ceramic Society, Volume 109, Issue 11, November 2026.ABSTRACT The interpretation of commercial soda‐lime‐silicate and related silicate glass properties through existing topological approaches has received little attention, despite its potential to clarify the relationship between glass chemistry and material properties, including crystallization, physical characteristics, and mechanical behavior ...
Erhan Kilinc, Russell J. Hand
wiley +1 more source
Journal of the American Ceramic Society, Volume 109, Issue 11, November 2026.ABSTRACT Improving the crack resistance (CR) in oxide glass remains a significant challenge in the field of damage tolerance, particularly in scenarios involving sharp contact loading. In this study, lithium‐, sodium‐, and potassium‐aluminoborate glasses with compositions ranging from 50 to 80 mol.% B2O3 were prepared to investigate the interplay ...
Nathan Kail +5 more
wiley +1 more source
Contrast‐Enhanced Ultrasonography of Orbital and Intraocular Pathologies in 24 Dogs and 6 Cats
Veterinary Ophthalmology, Volume 29, Issue 6, November 2026.ABSTRACT Objective Contrast‐enhanced ultrasonography (CEUS) is a noninvasive and relatively safe imaging technique to assess ocular perfusion, showing high sensitivity and specificity for tumor characterization in human oncology, while reports on its application in canine and feline diseased eyes are limited.
Janneke I. Ortner +3 more
wiley +1 more source