Results 81 to 90 of about 20,449 (205)
Recruitment of Vitronectin by Bacterial Pathogens: A Comprehensive Overview
The key factor that enables pathogenic bacteria to establish successful infections lies largely in their ability to escape the host’s immune response and adhere to host surfaces.
Angelica Pellegrini +1 more
doaj +1 more source
Controlling the protein corona formation onto carbon nanomaterials (CNMs) enhances their functionalities as platforms for cancer theranostics. Here, we reviewed the effects of the intrinsic and acquired properties of CNMs on protein corona formation, the consequent biological and toxicological outcomes, and the strategies to reshape corona formation ...
Yajuan Zou +5 more
wiley +1 more source
Adherent cells are highly sensitive to the physical and biochemical properties of their microenvironment, particularly the extracellular matrix (ECM), which regulates cell adhesion, signaling, and overall behavior.
Mathilde Hindié +6 more
doaj +1 more source
HIV Modulates Osteoblast Differentiation via Upregulation of RANKL and Vitronectin
Bone loss is a prevalent characteristic among people with HIV (PWH). We focused on mesenchymal stem cells (MSCs) and osteoblasts, examining their susceptibility to different HIV strains (R5- and X4-tropic) and the subsequent effects on bone tissue ...
Rosa Nicole Freiberger +8 more
doaj +1 more source
A developmentally inspired bioprinting approach enables the fabrication of pluripotent tissues that undergo shape‐morphing and in situ cardiac lineage specification. This method employs embedded bioprinting to deposit iPSCs within soft granular hydrogels to create pluripotent tissue constructs that undergo cell‐mediated shape morphogenesis.
Ankita Pramanick +8 more
wiley +1 more source
The Role of CAF‐derived Vitronectin in Promoting Colorectal Cancer Progression and Immunosuppression
Cancer‐associated fibroblasts (CAFs) dominate the tumor stroma in colorectal cancer (CRC), fostering an immunosuppressive microenvironment that supports tumor growth, metastasis, and therapy resistance.
Jiahua Yu +5 more
doaj +1 more source
Binding of Brucella protein, Bp26, to select extracellular matrix molecules
Background Brucella is a facultative intracellular pathogen responsible for zoonotic disease brucellosis. Little is known about the molecular basis of Brucella adherence to host cells. In the present study, the possible role of Bp26 protein as an adhesin
Yasmin ElTahir +7 more
doaj +1 more source
ABSTRACT Background Sarcopenia is characterized by progressive loss of muscle mass, strength and physical performance, yet current diagnostic tools are limited for practical and longitudinal monitoring. Extracellular vesicles (EVs) encapsulate various biomolecules, including proteins, nucleic acids, lipids and metabolites and have emerged as promising ...
Ji Yeon Kim +11 more
wiley +1 more source
Hybrid PLGA–corneal ECM biomembrane for ocular progenitor cell support and progenitor retinal cytoprotection. A hybrid biomembrane composed of PLGA and decellularized corneal extracellular matrix was developed to create a biomimetic microenvironment for ocular progenitor cells.
Ana Karulline Garcia Ungaratti +7 more
wiley +1 more source
Tumor Plasticity and Microenvironmental Crosstalk as Drivers of Metastasis and Therapy Resistance
The graphical abstract is a schematic illustration of the bidirectional crosstalk between tumor plasticity and the tumor microenvironment (TME) in driving metastasis and therapy resistance. Tumor‐intrinsic factors such as genetic mutations and epigenetic reprogramming enable dynamic transitions between epithelial, mesenchymal, and cancer stem cell ...
Gunjan Dagar +12 more
wiley +1 more source

