Results 101 to 110 of about 13,082 (286)
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Relative vividness ratings for Experiment 1.
, 2016 Error bars are SEM. Y-axis is the reported vividness of the action block relative to the vividness of the stationary block after the condition's action was performed. Negative values mean the action block was less vivid or faded more than the stationary (
Jessica Tinker (2557915) +1 more
core +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
The association between vividness and verbal and figural creativity
, 2017 Research on creativity in the technical field considers that one specific skill in the domain is spatial visualization, seeing with the eyes of the mind.
Victor Adîr, Beatrice Adriana Balgiu
core +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
, 2015 Habil(25) ile Kabil(25) sıkı iki arkadaştır. İkisi de işçidir. Birlikte bir yük taşıma işi yaparlar. İşveren kişi paralarını bir gün sonra ödeyeceğini söyler. Ertesi gün Kabil'in bir işi çıkar. Parayı almaya gidecek zamanı olmaz. Habil iş sahibine gidip yaptıkları işin ücretini almaya giderken borçlu olduğu bir adamla karşılaşır.
openaire +2 more sources
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
The effects of picture degradation on vividness ratings.
, 2013 Picture degradation reduced picture vividness, and this vividness loss was overall more pronounced following size reduction compared to picture blurring.
Andrea De Cesarei (360880) +1 more
core +1 more source