Results 111 to 120 of about 43,625 (305)
Neural network topologies supporting individual variations in vividness of visual imagery
NeuroImageVividness of visual imagery varies considerably across individuals, yet its neural underpinnings remain unclear. As emphasized in recent debates, a key controversy is whether early sensory architecture explains imagery or whether it is explained by ...
Timo L. Kvamme +9 more
doaj +1 more source
Prospective cognitions in anxiety and depression: Replication and methodological extension [PDF]
, 2000 The present study presents a replication and methodological extension of MacLeod, Tata, Kentish, and Jacobsen (1997) with a nonclinical sample, using future-directed imagery to assess prospective cognitions.
Alloy L. B. +5 more
core +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Partial Evidence: An enquiry concerning a possible affinity between literary moral cognitivism and moral pluralism [PDF]
, 2017 This paper begins by affirming the view that if there is a debate to be had over whether literature can convey moral knowledge, then efforts by proponents to substantiate this claim will already be necessarily conditioned by an understanding of what ...
Shum, Peter
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
A Systematic Review of Aphantasia: Concept, Measurement, Neural Basis, and Theory Development
VisionPeople with aphantasia exhibit the inability to voluntarily generate or form mental imagery in their minds. Since the term “aphantasia” was proposed to describe this, it has gained increasing attention from psychiatrists, neuroscientists, and clinicians.
Feiyang Jin, Shen-Mou Hsu, Yu Li
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Kinesthetic imagery: does it exist and how can we measure it? [PDF]
, 2005 [Introduction]: The emergence of sport psychology has influenced how athletes train and compete. Increasingly, coaches and athletes are incorporating mental as well as physical skills into their training programs and competition routines.
Burton, Lorelle, Dun, Kristine
core
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source