Results 81 to 90 of about 43,032 (288)

Can virtual nature improve patient experiences and memories of dental treatment? A study protocol for a randomized controlled trial [PDF]

open access: yes, 2014
Background Dental anxiety and anxiety-related avoidance of dental care create significant problems for patients and the dental profession. Distraction interventions are used in daily medical practice to help patients cope with unpleasant procedures ...
Andrade, J   +10 more
core   +4 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

How choice reveals and shapes expected hedonic outcome [PDF]

open access: yes, 2009
Humans tend to modify their attitudes to align with past action. For example, after choosing between similarly valued alternatives, people rate the selected option as better than they originally did, and the rejected option as worse.
De Martino, Benedetto   +2 more
core   +1 more source

An exploratory study of imagining sounds and “hearing” music in autism [PDF]

open access: yes, 2020
Individuals with autism spectrum disorder (ASD) reportedly possess preserved or superior music-processing skills compared to their typically developing counterparts. We examined auditory imagery and earworms (tunes that get “stuck” in the head) in adults
Bacon, Alex   +2 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Equivocal and Deceitful Didactic Poetry. What Style matters can say about Empedocles' audience

open access: yesArchai: Revista de Estudos sobre as Origens do Pensamento Ocidental
Since antiquity, Empedocles has been considered as an example of both successful and unsuccessful communication. Aristotle credits him with vividness of images, but blames him for failure of clarity, and eventually compares his obscureness to that of ...
Ilaria Andolfi
doaj   +1 more source

Impact of an interactive anti-speeding threat appeal: how much threat is too much? [PDF]

open access: yes, 2011
This study investigates the impact of an interactive television public service announcement (PSA) containing an anti-speeding threat appeal on feelings of telepresence and behavioral intention.
Cauberghe, Veroline   +2 more
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

The effect of eye movements on traumatic memories and the susceptibility to misinformation : a partial replication : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Psychology at Massey University, Manawatū, New Zealand [PDF]

open access: yes, 2018
The issue of whether certain techniques used in psychotherapy might increase false memories is a major source of contention between cognitive and practising psychologists. Recently, a study by Houben, Otgaar, Merckelbach, and Roelofs (2018) found that
Sievwright, Olivia
core  

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

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