Results 261 to 270 of about 66,180 (284)
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Metabolism of VLDL and LDL subclasses
Current Opinion in Lipidology, 1994The recognition of lipoprotein heterogeneity has given new depth to our understanding of lipoprotein metabolism and the role of plasma triglyceride as a determinant of lipoprotein subclass distribution and potential atherogenicity. It has also provided insight into the relationship between exogenous and endogenous lipid transport pathways, the roles of
Bruce A. Griffin, Christopher J. Packard
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Estimation of VLDL cholesterol in hyperlipidemia
Clinica Chimica Acta, 1985Lipoprotein data from 10947 fasting blood samples drawn between 1968 and 1982 in the Molecular Disease Branch at the National Institutes of Health were used to test the generalizability of estimating very low density lipoprotein cholesterol (VLDL-C) from plasma triglyceride (TG).
L. A. Zech +6 more
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IDL, VLDL, chylomicrons and atherosclerosis
European Journal of Epidemiology, 1992In humans with the lipoprotein lipase deficiency disorder large amounts of chylomicrons and large very low-density lipoprotein (VLDL) accumulate in plasma. In spite of this, atherosclerosis does not seem to develop at an accelerated rate, suggesting that these lipoproteins do not promote atherogenesis.
A. Tybjærg-Hansen +1 more
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Canadian Journal of Physiology and Pharmacology, 2023
Avoiding hepatic steatosis is crucial for preventing liver dysfunction, and one mechanism by which this is accomplished is through synchronization of the rate of very low density lipoprotein (VLDL) synthesis with its secretion. Endoplasmic reticulum (ER)-to-Golgi transport of nascent VLDL is the rate-limiting step in its secretion and is mediated by ...
Ryan Clay +2 more
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Avoiding hepatic steatosis is crucial for preventing liver dysfunction, and one mechanism by which this is accomplished is through synchronization of the rate of very low density lipoprotein (VLDL) synthesis with its secretion. Endoplasmic reticulum (ER)-to-Golgi transport of nascent VLDL is the rate-limiting step in its secretion and is mediated by ...
Ryan Clay +2 more
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Biochemical Journal, 2012
Metabolism under hypoxia is significantly different from that under normoxia. It has been well elucidated that HIF-1 (hypoxia-inducible factor-1) plays a central role in regulating glucose metabolism under hypoxia; however, the role of HIF-1 in lipid ...
G. Shen +8 more
semanticscholar +1 more source
Metabolism under hypoxia is significantly different from that under normoxia. It has been well elucidated that HIF-1 (hypoxia-inducible factor-1) plays a central role in regulating glucose metabolism under hypoxia; however, the role of HIF-1 in lipid ...
G. Shen +8 more
semanticscholar +1 more source
Metabolism of n-VLDL and β-VLDL in peritoneal macrophages from diabetic mice
Journal of Tongji Medical University, 1989Peritoneal macrophages were harvested from both healthy mice and mice with diabetes induced by intravenous injection of streptozotocin. After incubation with normal plasma very low density lipoprotein (n-VLDL) from swine for 24 h, the content of triglyceride (TG) in macrophages from diabetic mice was higher than that in the controls, and it was the ...
Ze-lan Wei +5 more
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Hyperinsulinemia and VLDL Kinetics
1993The most frequent lipoprotein abnormality in diabetes mellitus is hypertriglyceridemia. The frequency of hypercholesterolemia is not very different from that found in the nondiabetic population.1,2 In those diabetic individuals who are grossly insulin deficient, the hypertriglyceridemia is due to an accumulation of chylomicrons, the primary ...
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1977
Of the methods to measure VLDL triglyceride (TG) turnover in humans, the simplest is that utilizing 3H-glycerol. We showed that when simultaneous measurements were made with the radioglycerol method and the lipolytic rate method, a method which depends on different assumptions, similar turnover rates were obtained (Steiner and Murase, 1975). This paper
Georg Steiner, Dan Streja
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Of the methods to measure VLDL triglyceride (TG) turnover in humans, the simplest is that utilizing 3H-glycerol. We showed that when simultaneous measurements were made with the radioglycerol method and the lipolytic rate method, a method which depends on different assumptions, similar turnover rates were obtained (Steiner and Murase, 1975). This paper
Georg Steiner, Dan Streja
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Diabetes, 1993
The effects of short-term hyperinsulinemia on the production of both VLDL triglyceride and VLDL apoB were determined semiquantitatively before and during a 6-h euglycemic hyperinsulinemic clamp (40 mU · m−2 · min−1) in 17 women (8 chronically hyperinsulinemic obese, BMI = 35.7 kg/m2; 9 normal weight, BMI = 22.5 kg/m2).
Gary F. Lewis +3 more
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The effects of short-term hyperinsulinemia on the production of both VLDL triglyceride and VLDL apoB were determined semiquantitatively before and during a 6-h euglycemic hyperinsulinemic clamp (40 mU · m−2 · min−1) in 17 women (8 chronically hyperinsulinemic obese, BMI = 35.7 kg/m2; 9 normal weight, BMI = 22.5 kg/m2).
Gary F. Lewis +3 more
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Effects of VLDL and Remnant Particles on Platelets
Pathophysiology of Haemostasis and Thrombosis, 2006There is a considerable body of evidence supporting an association between hypertriglyceridaemia, a hypercoagulable state and atherothrombosis. A disorder of triglyceride metabolism is a key feature of the metabolic syndrome that increases risk of both ischaemic heart disease and type 2 diabetes approximately 3-fold. An increasing prevalence of obesity
Olufadi, Rasaq, Byrne, Christopher D.
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