Loss of vesicular dopamine release precedes tauopathy in degenerative dopaminergic neurons in a Drosophila model expressing human tau. [PDF]
, 2013 While a number of genome-wide association studies have identified microtubule-associated protein tau as a strong risk factor for Parkinson's disease (PD), little is known about the mechanism through which human tau can predispose an individual to this ...
Chang, Hui-Yun +6 more
core +2 more sources
Dosimetric Comparison of Tangential Volumetric Arc Therapy and Half Beam Volumetric Modulated Arc Therapy Planning Technique for Carcinoma of the Breast [PDF]
Iranian Journal of Medical PhysicsIntroduction: This study aims to compare tangential volumetric modulated arc therapy with half beam volumetric modulated arc therapy in the treatment of cancer in the left and right breasts.
Shreekripa Rao +3 more
doaj +1 more source
Frontiers in Oncology, 2021 BackgroundAlthough there are some controversies regarding whole pelvic radiation therapy (WPRT) due to its gastrointestinal and hematologic toxicities, it is considered for patients with gynecological, rectal, and prostate cancer.
Hyunsoo Jang +16 more
doaj +1 more source
Lipid peroxidation and apoptotic response in rat brain areas induced by long-term administration of nandrolone: the mutual crosstalk between ROS and NF-kB [PDF]
, 2016 The aim of this study was to evaluate the played by oxidative stress in the apoptotic response in different brain areas of rats chronically treated with supra-physiological doses of nandrolone decanoate (ND).
Busardo', FRANCESCO PAOLO +9 more
core +2 more sources
Precision Radiation Oncology, 2021 Objective We aimed to compare the dosimetric characteristics of 6‐MV flattening filter mode (FF) and flattening filter‐free mode (FFF) volumetric‐modulated arc therapy (VMAT) plans in preoperative radiotherapy for rectal cancer using an Edge linear ...
Zhen Ding +5 more
doaj +1 more source
Dosimetric Performance and Planning/Delivery Efficiency of a Dual-Layer Stacked and Staggered MLC on Treating Multiple Small Targets: A Planning Study Based on Single-Isocenter Multi-Target Stereotactic Radiosurgery (SRS) to Brain Metastases. [PDF]
, 2019 Purpose: To evaluate the dosimetric performance and planning/delivery efficiency of a dual-layer MLC system for treating multiple brain metastases with a single isocenter.
Alonso-Basanta, Michelle +8 more
core +2 more sources
Total Workload for Radioactive Facilities with Volumetric Modulated Arc Treatment
Brazilian Journal of Radiation Sciences, 2019 In recent years, there have been major changes in radiotherapy, particularly in dose delivery for treatments using the techniques of Three-Dimensional Conformal Radiation Therapy (3D-CRT), Intensity-Modulated Radiation Therapy (IMRT) and Volumetric ...
Juraci Passos Reis +2 more
doaj +1 more source
Radiation Oncology, 2020 Background Although whole brain radiation therapy (WBRT) provides palliation and prophylaxis, reduces local recurrence probability and improves overall survival, it is evident that WBRT is associated with neurocognitive deficits due to radiation induced ...
Adams Hei Long Yuen +3 more
doaj +1 more source
South African Journal of Oncology, 2021 Background: External beam radiotherapy (EBRT) is essential in the management of locally advanced cervical cancer (LACC). Volumetric modulated arc therapy (VMAT) is thought to achieve higher conformity to the planned target volume (PTV) and better sparing
Visham Bhagaloo +3 more
doaj +1 more source
Modeling dose to normal brain following hypofractionated stereotactic radiotherapy to a single brain metastasis. [PDF]
J Appl Clin Med PhysAbstract Background Brain metastases (BM) occur in at least 20% of people with an advanced solid malignancy and can lead to morbidity or mortality if not controlled. Hypofractionated stereotactic radiotherapy (HF‐SRT) may be preferred to single fraction stereotactic radiosurgery (SRS) in certain clinical situations to improve the therapeutic ratio ...
Johns E +5 more
europepmc +2 more sources