Results 141 to 150 of about 32,741 (282)
Re-definition of VMD and Necessary Elements
, 2021 VMD（ビジュアルマーチャンダイジング）戦略は、リテールにおけるビジネスモデルの「マーチャンダイジングの視覚化」という概念で、購買のフックとして機能することがその目的と考えられてきた。しかし、ECでの購買が主流になり、リアル店舗は、「ショールーム」や「ネット販売の拠点」化していく今、VMDに必要なのは、購買行動の入口だけに留まらず、顧客心理に寄り添いカスタマージャーニーの全てに関わっていくことである。来店の理由を生み出し、期待をもって来店した顧客に新しい発見や体験を通して ...
荒木 , 淳一郎
core
Stoichiometric Binding of Cyclophilin‐A to The HIV‐1 Capsid Modulates Its Mechanoelastic Properties
Small, EarlyView.The HIV‐1 capsid is a protein nanocapsule that must balance rigidity and flexibility to enter the cell nucleus. Atomic force microscopy simulations reveal that binding of the host protein Cyclophilin A tunes this mechanical response: partial coverage preserves deformability, while excessive binding induces brittleness and failure.
Juan S. Rey +2 more
wiley +1 more source
Small Methods, EarlyView.Nanopore technology has revolutionized single‐molecule sensing, yet it suffers from an inherent interpretive challenge. Molecular dynamics has emerged as a go‐to method for determining the relationship between the structure of translocating molecules and the nanopore current signals.
Behzad Mehrafrooz +5 more
wiley +1 more source
Wildlife Biology, EarlyView.Exploration of new wildlife surveying methodologies that leverage advances in sensor technology and machine learning has led to tentative research into the application of seismology techniques. This, most commonly, involves the deployment of a footfall trap – a seismic sensor and data logger customised for wildlife footfall.
Benjamin J. Blackledge +4 more
wiley +1 more source
Zeitschrift für anorganische und allgemeine Chemie, EarlyView.Pore‐size‐controlled nanoconfinement of rubrene within UiO‐66 and UiO‐67 suppresses aggregation‐caused quenching and restores bright solid‐state emission. Geometric exclusion and energetic destabilization prevent parallel stacking, yielding solution‐like absorption and fluorescence quantum yields up to 25%.
Julia Larcher +6 more
wiley +1 more source
International Journal of Nursing Knowledge, EarlyView.Abstract Purpose To evaluate the evidence of internal structure validity of the nursing outcome (NO) “Mechanical Ventilation Weaning Response: Adult (0412)” of the NOs classification for critically ill COVID‐19 patients. Methods A methodological study focused on internal structural validation, part of a multicenter study, was carried out in the ...
Aline Batista Maurício +8 more
wiley +1 more source
PEG400 regulates Falcipain 2 activity through an allosteric mechanism
The FEBS Journal, EarlyView.Falcipain‐2 can potentially be leveraged as a drug target due to its critical role as a haemoglobinase during the intra‐erythrocytic stage of Plasmodium falciparum. Here, we investigate the regulation of the proteolytic and haemoglobinase activity of falcipain‐2 in the presence of polyethylene glycol.
Bikram Nath +2 more
wiley +1 more source
The FEBS Journal, EarlyView.We investigated the potential of iloperidone as an activator of Sigma‐1 receptor (S1R) neuroprotective function in juvenile Huntington's disease (jHD). We tested iloperidone on cortical neurons differentiated from patient‐derived iPSCs, demonstrating that it acts as a S1R agonist, decreasing apoptosis, huntingtin aggregation, and oxidative stress ...
Ersilia Fornetti +11 more
wiley +1 more source
The FEBS Journal, EarlyView.Xylan, the second most abundant plant cell wall polysaccharide, is degraded by β‐xylanases and β‐xylosidases. Here, we present the 2.65 Å cryo‐EM structure of Enterobacter cloacae β‐xylosidase (EcXyl43, GH43) and the 2.4 Å X‐ray structure of its inactive F507A mutant.
Lorenzo Briganti +8 more
wiley +1 more source
The FEBS Journal, EarlyView.Athe_2052 is an ABC transporter substrate‐binding protein that recognizes xyloglucan heptasaccharide (XXXG), a soluble breakdown product of plant xyloglucan. The crystal structure of Athe_2052, together with binding assays and computational modeling, shows how XXXG is recognized by this sugar transporter.
Hansen Tjo +6 more
wiley +1 more source