Results 11 to 20 of about 48,688 (308)

High intensity VNS disrupts VNS-mediated plasticity in motor cortex [PDF]

Brain Research, 2021
Vagus nerve stimulation (VNS) paired with motor rehabilitation enhances recovery of function after neurological injury in rats and humans. This effect is ascribed to VNS-dependent facilitation of plasticity in motor networks. Previous studies document an inverted-U relationship between VNS intensity and cortical plasticity, such that moderate ...
Robert A. Morrison, Tanya T. Danaphongse, Stephanie T. Abe, Madison E. Stevens, Vikram Ezhil, Armin Seyedahmadi, Katherine S. Adcock, Robert L. Rennaker, Michael P. Kilgard, Seth A. Hays   +9 more
openaire   +3 more sources

Treatment of chronic migraine with transcutaneous stimulation of the auricular branch of the vagal nerve (auricular t-VNS): a randomized, monocentric clinical trial [PDF]

The Journal of Headache and Pain, 2015
BackgroundAim of the study was assessment of efficacy and safety of transcutaneous stimulation of the auricular branch of the vagal nerve (t-VNS) in the treatment of chronic migraine.MethodsA monocentric, randomized, controlled, double-blind study was ...
Andreas Straube, Jens Ellrich, Ozan Eren, Bernhard Blum, Ruth Ruscheweyh   +4 more
openalex   +2 more sources

A Review of Parameter Settings for Invasive and Non-invasive Vagus Nerve Stimulation (VNS) Applied in Neurological and Psychiatric Disorders [PDF]

Frontiers in Neuroscience, 2021
Vagus nerve stimulation (VNS) is an established form of neuromodulation with a long history of promising applications. Earliest reports of VNS in the literature date to the late 1800’s in experiments conducted by Dr. James Corning. Over the past century,
Sean Thompson, Georgia H. O’Leary, Christopher W. Austelle, Elise Gruber, Alex T. Kahn, Andrew J. Manett, Baron Short, Bashar W. Badran   +7 more
openalex   +2 more sources

Evolution of the Vagus Nerve Stimulation (VNS) Therapy System Technology for Drug-Resistant Epilepsy

Frontiers in Medical Technology, 2021
The vagus nerve stimulation (VNS) Therapy® System is the first FDA-approved medical device therapy for the treatment of drug-resistant epilepsy. Over the past two decades, the technology has evolved through multiple iterations resulting in software ...
P. Afra, B. Adamolekun, Seyhmus Aydemir, G. Watson   +3 more
semanticscholar   +1 more source

Vagus Nerve Stimulation Paired With Rehabilitation for Upper Limb Motor Impairment and Function After Chronic Ischemic Stroke: Subgroup Analysis of the Randomized, Blinded, Pivotal, VNS-REHAB Device Trial

Neurorehabilitation and Neural Repair, 2022
Background Vagus Nerve Stimulation (VNS) paired with rehabilitation improved upper extremity impairment and function in a recent pivotal, randomized, triple-blind, sham-controlled trial in people with chronic arm weakness after stroke. Objective We aimed
Jesse Dawson, N. Engineer, Steven C. Cramer, S. Wolf, Rushna Ali, M. O'dell, David Pierce, Cecília N. Prudente, J. Redgrave, Wuwei Feng, Charles Y Liu, G. Francisco, Benjamin L Brown, A. Dixit, Jen Alexander, Louis DeMark, Vibor Krishna, S. Kautz, A. Majid, Brent W. Tarver, D. Turner, T. Kimberley   +21 more
semanticscholar   +1 more source

Efficacy and safety of VNS therapy or continued medication management for treatment of adults with drug-resistant epilepsy: systematic review and meta-analysis

Journal of Neurology, 2021
Vagus nerve stimulation (VNS) Therapy® is an adjunctive neurostimulation treatment for people with drug-resistant epilepsy (DRE) who are unwilling to undergo resective surgery, have had unsuccessful surgery or are unsuitable for surgery.
J. Conry, S. Batson, S. Mitchell, R. Shankar, J. Boggs, Rodney Radtke, F. Barion, Joanna Murphy, V. Danielson   +8 more
semanticscholar   +1 more source

Vagus nerve stimulation therapy in people with drug-resistant epilepsy (CORE-VNS): rationale and design of a real-world post-market comprehensive outcomes registry

BMJ Neurology Open, 2021
Introduction The Vagus Nerve Stimulation Therapy System (VNS Therapy) is an adjunctive neuromodulatory therapy that can be efficacious in reducing the frequency and severity of seizures in people with drug-resistant epilepsy (DRE).
Arjune Sen, Ryan Verner, J. Valeriano, Ricky W. Lee, Muhammad Zafar, R. Thomas, K. Kotulska, Ellen Jespers, M. Dibué, Patrick S L Kwan   +9 more
semanticscholar   +1 more source

Timing of vagus nerve stimulation during fear extinction determines efficacy in a rat model of PTSD

Scientific Reports, 2022
Studies have indicated that vagus nerve stimulation (VNS) enhances extinction learning in rodent models. Here, we investigated if pairing VNS with the conditioned stimulus is required for the enhancing effects of VNS.
Rimenez R. Souza, Mark B. Powers, Robert L. Rennaker, Christa K. McIntyre, Seth A. Hays, Michael P. Kilgard   +5 more
doaj   +1 more source

Continuous vagus nerve stimulation exerts beneficial effects on rats with experimentally induced Parkinson's disease: Evidence suggesting involvement of a vagal afferent pathway

Brain Stimulation, 2023
Background: Vagus nerve stimulation (VNS) exerts neuroprotective and anti-inflammatory effects in preclinical models of central nervous system disorders, including Parkinson's disease (PD).
Kakeru Hosomoto, Tatsuya Sasaki, Takao Yasuhara, Masahiro Kameda, Susumu Sasada, Ittetsu Kin, Ken Kuwahara, Satoshi Kawauchi, Yosuke Okazaki, Satoru Yabuno, Chiaki Sugahara, Koji Kawai, Takayuki Nagase, Shun Tanimoto, Cesario V. Borlongan, Isao Date   +15 more
doaj   +1 more source

PPAR-γ Mediates Ta-VNS-Induced Angiogenesis and Subsequent Functional Recovery after Experimental Stroke in Rats

BioMed Research International, 2020
Background Neoangiogenesis after cerebral ischemia in mammals is insufficient to restore neurological function, illustrating the need to design better strategies for improving outcomes. Our previous study has suggested that transcutaneous auricular vagus
Jiani Li, Keming Zhang, Qinbin Zhang, Xueling Zhou, Lan Wen, Jingxi Ma, Lingchuan Niu, Changqing Li   +7 more
semanticscholar   +1 more source