Results 41 to 50 of about 16,357 (238)

Detailed schematic of the experimental VNS protocol.

, 2018
Standard P-VNS or S-VNS with different degree of stochasticity (STOCH, 10% and 20%) was administered across different frequencies (FREQ, 20, 30, and 10 Hz) with stabilization times between protocols and conditions. P-VNS, periodic vagus nerve stimulation;
Elizabeth M. Annoni (5029715), Bruce H. KenKnight (5029721), Elena G. Tolkacheva (3942389), Imad Libbus (5029718), Kanchan Kulkarni (5029712), Steven W. Lee (5029724)   +5 more
core   +1 more source

Genetic testing among patients evaluated for epilepsy surgery

Epileptic Disorders, EarlyView.
Abstract Objective Genetic testing performed to identify the underlying etiology of epilepsy has become increasingly common and is now being recommended as part of the presurgical evaluation for epilepsy surgery. This study aimed to characterize the types of genetic tests performed in patients evaluated for epilepsy surgery and assess how genetic ...
Anni Saarela, Veera‐Julia Kuronen, Oskari Timonen, Leena Jutila, Katri Silvennoinen, Annemari Kilpeläinen, Jarkko Kirjavainen, Reetta Kälviäinen   +7 more
wiley   +1 more source

The potential of invasive and non-invasive vagus nerve stimulation to improve verbal memory performance in epilepsy patients

Scientific Reports, 2022
It has been demonstrated that acute vagus nerve stimulation (VNS) improves word recognition memory in epilepsy patients. Transcutaneous auricular vagus nerve stimulation (taVNS) has gained interest as a non-invasive alternative to improve cognition.
Ann Mertens, Stefanie Gadeyne, Emma Lescrauwaet, Evelien Carrette, Alfred Meurs, Veerle De Herdt, Frank Dewaele, Robrecht Raedt, Marijke Miatton, Paul Boon, Kristl Vonck   +10 more
doaj   +1 more source

Artificial intelligence for adaptive neuromodulation in drug‐resistant epilepsy

Epilepsia, EarlyView.
Abstract Drug‐resistant epilepsy (DRE) affects nearly one third of people with epilepsy and is associated with substantial cognitive, psychiatric, and mortality burdens. For patients who are not candidates for resection or laser interstitial thermal therapy, neuromodulation therapies such as vagus nerve stimulation, deep brain stimulation, and ...
Amir Hossein Daraie, Arianna Damiani, Mahsa Khoshkhou, Luis A. Sanchez, Rachel J. Smith, Shruti H. Agashe, Jorge A. Gonzalez‐Martinez, Jennifer Hopp, Adam S. Charles, Sridevi V. Sarma, Joon‐Yi Kang   +10 more
wiley   +1 more source

Possible relationship between vagus nerve stimulation and ictal discharges revealed by long-term electroencephalographic and electrocorticographic monitoring in a non-responsive patient

Interdisciplinary Neurosurgery, 2021
Background: Vagus nerve stimulation (VNS) is a well-known palliative therapy for refractory epilepsy. However, some non-responsive patients experience persistent epileptic seizures after VNS.
Takafumi Shimogawa, Nobutaka Mukae, Takato Morioka, Shunya Tanaka, Ayumi Sakata, Taira Uehara, Masahiro Mizoguchi   +6 more
doaj   +1 more source

VNS in children : more than just seizure reduction [PDF]

, 2015
This dissertation aims to gain more insight into the effects of vagus nerve stimulation (VNS) in children with hard-to-treat epilepsy. VNS appears to be both a tolerable and safe form of treatment. Predictors of a favourable outcome with VNS therapy were
Klinkenberg, S.
core   +4 more sources

Gamma suppression correlates with thalamic stimulation therapeutic response in intractable epilepsy

Epilepsia, EarlyView.
Abstract Objective In patients with drug‐resistant epilepsy who undergo anterior nucleus of the thalamus (ANT) deep brain stimulation (DBS), efficacy is assessed months after therapy initiation and clinicians have no guidance when choosing stimulation parameters due to the lack of real‐time biomarkers.
Zachary T. Sanger, Xinbing Zhang, Thomas Lisko, Hafsa Farooqi, Steffen Ventz, Sandipan Pati, Thomas R. Henry, David P. Darrow, Michael C. Park, Theoden I. Netoff, Robert A. McGovern   +10 more
wiley   +1 more source

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). II. Treatments in more advanced clinical development

Epilepsia, EarlyView.
Abstract This article summarizes data for 13 investigational treatments for which at least preliminary seizure outcome data in patients with epilepsy were reported at the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices held in Madrid, Spain, on May 3–6, 2026.
Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell   +7 more
wiley   +1 more source

Vagus Nerve Stimulation Reduces Neuroinflammation Through Microglia Polarization Regulation to Improve Functional Recovery After Spinal Cord Injury

Frontiers in Neuroscience, 2022
BackgroundSpinal cord injury (SCI) is a devastating disease that lacks effective treatment. Interestingly, recent studies indicated that vagus nerve stimulation (VNS), neuromodulation that is widely used in a variety of central nervous system (CNS ...
Hui Chen, Zhou Feng, Lingxia Min, Weiwei Deng, Mingliang Tan, Jian Hong, Qiuwen Gong, Dongyun Zhang, Hongliang Liu, Jingming Hou   +9 more
doaj   +1 more source

Effects of STOCH on the chronotropic effects of VNS.

, 2018
Mean percent drop in HR for (A) S-VNS (10%) and (B) S-VNS (20%) being compared to its immediate preceding P-VNS protocol at different FREQ. (C) Comparison of mean relative drop in HR between P-VNS protocols and (D) S-VNS (20%) and its subsequent P-VNS ...
Elizabeth M. Annoni (5029715), Bruce H. KenKnight (5029721), Elena G. Tolkacheva (3942389), Imad Libbus (5029718), Kanchan Kulkarni (5029712), Steven W. Lee (5029724)   +5 more
core   +1 more source