Results 21 to 30 of about 16,357 (238)

Timing of vagus nerve stimulation during fear extinction determines efficacy in a rat model of PTSD

Scientific Reports, 2022
Studies have indicated that vagus nerve stimulation (VNS) enhances extinction learning in rodent models. Here, we investigated if pairing VNS with the conditioned stimulus is required for the enhancing effects of VNS.
Rimenez R. Souza, Mark B. Powers, Robert L. Rennaker, Christa K. McIntyre, Seth A. Hays, Michael P. Kilgard   +5 more
doaj   +1 more source

A variable neighborhood-based heuristic for the heterogeneous fleet vehicle routing problem [PDF]

, 2008
The heterogeneous fleet vehicle routing problem is investigated using some adaptations of the variable neighborhood search (VNS). The initial solution is obtained by Dijkstra's algorithm based on a cost network constructed by the sweep algorithm and the ...
Imran, Arif, Wassan, Niaz A., Salhi, Said   +2 more
core   +1 more source

Continuous vagus nerve stimulation exerts beneficial effects on rats with experimentally induced Parkinson's disease: Evidence suggesting involvement of a vagal afferent pathway

Brain Stimulation, 2023
Background: Vagus nerve stimulation (VNS) exerts neuroprotective and anti-inflammatory effects in preclinical models of central nervous system disorders, including Parkinson's disease (PD).
Kakeru Hosomoto, Tatsuya Sasaki, Takao Yasuhara, Masahiro Kameda, Susumu Sasada, Ittetsu Kin, Ken Kuwahara, Satoshi Kawauchi, Yosuke Okazaki, Satoru Yabuno, Chiaki Sugahara, Koji Kawai, Takayuki Nagase, Shun Tanimoto, Cesario V. Borlongan, Isao Date   +15 more
doaj   +1 more source

Variable neighborhood search for solving the balanced location problem

, 2012
In this paper we propose a general variable neighborhood search approach for the balanced location problem. Next to large shaking neighborhoods, the embedded variable neighborhood descent utilizes three neighborhood structures that focus on different ...
Leitner, Markus, Kratica, Jozef, Ljubic, Ivana   +2 more
core   +4 more sources

A proposal towards a VNS-based decision support tool for large scale location-covering-type problems [PDF]

Yugoslav Journal of Operations Research
We describe a number of typical features, constraints and objectives, frequently appearing in spatial system-design of maximum covering-type, such as emergency response systems.
Plastria Frank
doaj   +1 more source

Vagus Nerve Stimulation Amplifies Task-Induced Cerebral Blood Flow Increase

Frontiers in Human Neuroscience, 2021
BackgroundVagus nerve stimulation (VNS) is an established palliative surgical treatment for refractory epilepsy. Recently, pairing VNS with rehabilitation received growing attention for their joint effect on neural plasticity.
Naoto Kunii, Tomoyuki Koizumi, Kensuke Kawai, Seijiro Shimada, Nobuhito Saito   +4 more
doaj   +1 more source

Vagal nerve stimulation preserves right ventricular function in a rat model of right ventricular pressure overload

Pulmonary Circulation, 2022
Vagal nerve stimulation (VNS) ameliorates pulmonary vascular remodeling and improves survival in a rat model of pulmonary hypertension (PH). However, the direct impact of VNS on right ventricular (RV) function, which is the key predictor of PH patients ...
Keimei Yoshida, Keita Saku, Harm Jan Bogaard, Kohtaro Abe, Kenji Sunagawa, Hiroyuki Tsutsui   +5 more
doaj   +1 more source

Self-Administration of Right Vagus Nerve Stimulation Activates Midbrain Dopaminergic Nuclei

Frontiers in Neuroscience, 2021
Background: Left cervical vagus nerve stimulation (l-VNS) is an FDA-approved treatment for neurological disorders including epilepsy, major depressive disorder, and stroke, and l-VNS is increasingly under investigation for a range of other neurological ...
Jackson Brougher, Umaymah Aziz, Nikitha Adari, Muskaan Chaturvedi, Aryela Jules, Iqra Shah, Saba Syed, Catherine A. Thorn   +7 more
doaj   +1 more source

Treatment of vagus nerve stimulator-induced sleep-disordered breathing: A case series

Epilepsy & Behavior Reports, 2019
Objective: Vagus nerve stimulation (VNS) is a treatment option for patients with drug-resistant seizures, but it is also associated with sleep-disordered breathing (SDB).
Daniel M. Oh, Jacklyn Johnson, Bankim Shah, Sushanth Bhat, Rolla Nuoman, Xue Ming   +5 more
doaj   +1 more source

Identification of vagus nerve stimulation parameters affecting rat hippocampal electrophysiology without temperature effects

Brain Stimulation, 2020
Background: Recent experiments in rats have demonstrated significant effects of VNS on hippocampal excitability but were partially attributed to hypothermia, induced by the applied VNS parameters.
Wouter Van Lysebettens, Kristl Vonck, Lars Emil Larsen, Latoya Stevens, Charlotte Bouckaert, Charlotte Germonpré, Mathieu Sprengers, Evelien Carrette, Jean Delbeke, Wytse Jan Wadman, Paul Boon, Robrecht Raedt   +11 more
doaj   +1 more source