Results 11 to 20 of about 40,368 (229)

Vagus Nerve Stimulation in Refractory Epilepsy: Effects on Pro- and Anti-Inflammatory Cytokines in Peripheral Blood [PDF]

, 2010
Objective: The vagus nerve has important immunological functions that may be relevant for its anticonvulsive action. We postulate that this anticonvulsive action is activated by a shift in the immune system resulting in a reduction of neurotoxic and an ...
Berfelo, M. W., Hulsman, J. A. R. J., Majoie, H. J. M., Myint, A., Rijkers, K., Schwarz, M., Vles, J. S. H.   +6 more
core   +10 more sources

Timing of vagus nerve stimulation during fear extinction determines efficacy in a rat model of PTSD

Scientific Reports, 2022
Studies have indicated that vagus nerve stimulation (VNS) enhances extinction learning in rodent models. Here, we investigated if pairing VNS with the conditioned stimulus is required for the enhancing effects of VNS.
Rimenez R. Souza, Mark B. Powers, Robert L. Rennaker, Christa K. McIntyre, Seth A. Hays, Michael P. Kilgard   +5 more
doaj   +1 more source

Effect of vagus nerve stimulation against generalized seizure and status epilepticus recurrence

Frontiers in Neurology, 2023
ObjectiveVagus nerve stimulation (VNS) is a palliative surgery for drug-resistant epilepsy. The two objectives of this study were to (1) determine the seizure type most responsive to VNS and (2) investigate the preventive effect on status epilepticus (SE)
Yasushi Iimura, Yasushi Iimura, Hiroharu Suzuki, Hiroharu Suzuki, Takumi Mitsuhashi, Takumi Mitsuhashi, Tetsuya Ueda, Tetsuya Ueda, Kazuki Nishioka, Kazuki Nishioka, Kou Horikoshi, Kou Horikoshi, Kazuki Nomura, Kazuki Nomura, Hidenori Sugano, Hidenori Sugano, Hidenori Sugano, Akihide Kondo, Akihide Kondo   +18 more
doaj   +1 more source

Vagus nerve stimulation paired with tactile training improved sensory function in a chronic stroke patient [PDF]

, 2018
Background: Recent studies indicate that vagus nerve stimulation (VNS) paired with rehabilitation can enhance neural plasticity in the primary sensory and motor cortices, improve forelimb function after stroke in animal models and improve motor function ...
Alexander, Jen, Dawson, Jesse, Kilgard, Michael P., Rennaker, Robert L.   +3 more
core   +1 more source

How to fail with paired VNS therapy

Brain Stimulation, 2023
Vagus nerve stimulation (VNS) has gained enormous traction as a promising bioelectronic therapy. In particular, the delivery of VNS paired with training to promote neural changes has demonstrated clinical success for stroke recovery and found far ...
Seth A. Hays, Robert L. Rennaker, II, Michael P. Kilgard   +2 more
doaj   +1 more source

A VNS-based approach for solving the Manhattan metric straddle carrier routing problem with buffer areas [PDF]

Yugoslav Journal of Operations Research
This paper presents a metaheuristic approach for solving an optimization problem that arises at container terminals where straddle carriers (SCs) transport containers between the stacking areas and the seaside.
Cürebal Ahmet, Radojičić Nina, Heilig Leonard, Vos Stefan   +3 more
doaj   +1 more source

Continuous vagus nerve stimulation exerts beneficial effects on rats with experimentally induced Parkinson's disease: Evidence suggesting involvement of a vagal afferent pathway

Brain Stimulation, 2023
Background: Vagus nerve stimulation (VNS) exerts neuroprotective and anti-inflammatory effects in preclinical models of central nervous system disorders, including Parkinson's disease (PD).
Kakeru Hosomoto, Tatsuya Sasaki, Takao Yasuhara, Masahiro Kameda, Susumu Sasada, Ittetsu Kin, Ken Kuwahara, Satoshi Kawauchi, Yosuke Okazaki, Satoru Yabuno, Chiaki Sugahara, Koji Kawai, Takayuki Nagase, Shun Tanimoto, Cesario V. Borlongan, Isao Date   +15 more
doaj   +1 more source

The continuous p-centre problem: An investigation into variable neighbourhood search with memory [PDF]

, 2015
A VNS-based heuristic using both a facility as well as a customer type neighbourhood structure is proposed to solve the p-centre problem in the continuous space.
Abdalla Elshaikh, Al-Khedhairi, Chen, Cooper, Daskin, Drezner, Drezner, Eiselt, Elzinga, Gábor Nagy, Hansen, Hearn, Lu, Megiddo, Mladenović, Mladenović, Mladenović, Murray, Plastria, Said Salhi, Salhi, Suzuki, Wei, Xu   +23 more
core   +1 more source

High intensity VNS disrupts VNS-mediated plasticity in motor cortex [PDF]

Brain Research, 2021
Vagus nerve stimulation (VNS) paired with motor rehabilitation enhances recovery of function after neurological injury in rats and humans. This effect is ascribed to VNS-dependent facilitation of plasticity in motor networks. Previous studies document an inverted-U relationship between VNS intensity and cortical plasticity, such that moderate ...
Robert A. Morrison, Tanya T. Danaphongse, Stephanie T. Abe, Madison E. Stevens, Vikram Ezhil, Armin Seyedahmadi, Katherine S. Adcock, Robert L. Rennaker, Michael P. Kilgard, Seth A. Hays   +9 more
openaire   +2 more sources

A proposal towards a VNS-based decision support tool for large scale location-covering-type problems [PDF]

Yugoslav Journal of Operations Research
We describe a number of typical features, constraints and objectives, frequently appearing in spatial system-design of maximum covering-type, such as emergency response systems.
Plastria Frank
doaj   +1 more source