Structural morphometry distinguishes vagus nerve stimulation outcomes in individuals with epilepsy [PDF]
Epilepsia Open, EarlyView.Abstract Objective Vagus nerve stimulation (VNS) is a commonly used treatment for drug‐resistant epilepsy. However, response to VNS is variable, while understanding of this response variability is limited. The vagus afferent network (VagAN), the neural circuits thought to be involved in response to vagal afferents, has been implicated in response ...
Harry J. Clifford +9 more
wiley +2 more sources
Noninvasive or minimally invasive neuromodulation in animal models of acute ischemic stroke: A systematic review and meta‐analysis [PDF]
Neuroprotection, EarlyView.This systematic review and meta‐analysis assessed the cytoprotective effects of neuromodulation in preclinical models of ischemic stroke. Pooled analyses showed that neuromodulation significantly reduced infarct volume and improved neurological outcomes.
Igor Caitano Salles +7 more
wiley +2 more sources
Right vagus nerve stimulation promotes motor cortical plasticity [PDF]
Scientific ReportsStimulation of the left cervical vagus nerve (l-VNS) paired with motor training is FDA-approved to improve upper limb function after stroke. However, recent preclinical studies have revealed a striking asymmetry in engagement of the midbrain dopaminergic
Hailey F. Welch +2 more
doaj +2 more sources
Continuous vs. intermittent chronic vagus nerve stimulation: effects on T-cell dependent antibody response, heart rate variability and body weight in immunized mice [PDF]
Bioelectronic MedicineVagal-immune interactions are increasingly recognized to play a role in the pathogenesis of diseases associated with immune dysfunction. To study the direct effects of altered vagal activity on adaptive immune function and antibody production, we modeled
Michael Gerber +6 more
doaj +2 more sources
Reducing VNS stimulation parameters: Is it safe?
Brazilian Neurosurgery, 2022 Introduction Vagal nerve stimulation (VNS) is an adjuvant therapy used in the treatment of patients with refractory epilepsy who are not candidates for resective surgery or who have limited results after surgical procedures.
Tatiana Von Hertwig Fernandes de Oliveira +4 more
doaj +1 more source
Brain Sciences, 2021 Objective: The effectiveness of vagus nerve stimulation (VNS) for residual seizures after corpus callosotomy (CC) has not yet been fully investigated. We hypothesized that seizure control would be improved by VNS after CC.
Keisuke Hatano +4 more
doaj +1 more source
Stochastic vagus nerve stimulation affects acute heart rate dynamics in rats. [PDF]
PLoS ONE, 2018 Vagus nerve stimulation (VNS) is an approved therapy for treatment of epilepsy and depression. While also shown to be promising in several preclinical and clinical studies to treat cardiovascular diseases, optimal therapeutic stimulation paradigms are ...
Steven W Lee +5 more
doaj +1 more source
Solving the minimum labelling spanning tree problem using hybrid local search [PDF]
, 2007 Given a connected, undirected graph whose edges are labelled (or coloured), the minimum labelling spanning tree (MLST) problem seeks a spanning tree whose edges have the smallest number of distinct labels (or colours).
Moreno-Perez, J A +3 more
core +6 more sources
Effect of vagus nerve stimulation against generalized seizure and status epilepticus recurrence
Frontiers in Neurology, 2023 ObjectiveVagus nerve stimulation (VNS) is a palliative surgery for drug-resistant epilepsy. The two objectives of this study were to (1) determine the seizure type most responsive to VNS and (2) investigate the preventive effect on status epilepticus (SE)
Yasushi Iimura +18 more
doaj +1 more source
A VNS-based approach for solving the Manhattan metric straddle carrier routing problem with buffer areas [PDF]
Yugoslav Journal of Operations ResearchThis paper presents a metaheuristic approach for solving an optimization problem that arises at container terminals where straddle carriers (SCs) transport containers between the stacking areas and the seaside.
Cürebal Ahmet +3 more
doaj +1 more source