Results 51 to 60 of about 17,125 (241)

Vagus Nerve Stimulation Reduces Neuroinflammation Through Microglia Polarization Regulation to Improve Functional Recovery After Spinal Cord Injury

Frontiers in Neuroscience, 2022
BackgroundSpinal cord injury (SCI) is a devastating disease that lacks effective treatment. Interestingly, recent studies indicated that vagus nerve stimulation (VNS), neuromodulation that is widely used in a variety of central nervous system (CNS ...
Hui Chen, Zhou Feng, Lingxia Min, Weiwei Deng, Mingliang Tan, Jian Hong, Qiuwen Gong, Dongyun Zhang, Hongliang Liu, Jingming Hou   +9 more
doaj   +1 more source

Artificial intelligence for adaptive neuromodulation in drug‐resistant epilepsy

Epilepsia, EarlyView.
Abstract Drug‐resistant epilepsy (DRE) affects nearly one third of people with epilepsy and is associated with substantial cognitive, psychiatric, and mortality burdens. For patients who are not candidates for resection or laser interstitial thermal therapy, neuromodulation therapies such as vagus nerve stimulation, deep brain stimulation, and ...
Amir Hossein Daraie, Arianna Damiani, Mahsa Khoshkhou, Luis A. Sanchez, Rachel J. Smith, Shruti H. Agashe, Jorge A. Gonzalez‐Martinez, Jennifer Hopp, Adam S. Charles, Sridevi V. Sarma, Joon‐Yi Kang   +10 more
wiley   +1 more source

The Role of the Vagus Nerve in Depressive Disorders: A Literature Review and the Potential of Vagotomy to Create a Depression Phenotype in Rodents

Acta Medica Bulgarica
Major depressive disorder (MDD) affects 280 million people worldwide and is a major global health burden due to its link with suicide, physical comorbidities, and inadequate response to pharmacotherapy in many patients. The monoamine theory of depression
Ataker F., Pencheva D., Bakalov D.
doaj   +1 more source

The potential of invasive and non-invasive vagus nerve stimulation to improve verbal memory performance in epilepsy patients

Scientific Reports, 2022
It has been demonstrated that acute vagus nerve stimulation (VNS) improves word recognition memory in epilepsy patients. Transcutaneous auricular vagus nerve stimulation (taVNS) has gained interest as a non-invasive alternative to improve cognition.
Ann Mertens, Stefanie Gadeyne, Emma Lescrauwaet, Evelien Carrette, Alfred Meurs, Veerle De Herdt, Frank Dewaele, Robrecht Raedt, Marijke Miatton, Paul Boon, Kristl Vonck   +10 more
doaj   +1 more source

Oligogenic inheritance in epilepsy: A systematic exome‐wide analysis

Epilepsia, EarlyView.
Abstract Objective Genetic factors contribute to the majority of epilepsies, but the exact genetic cause remains unknown in most patients. Incomplete penetrance and variable expressivity are frequent, and recent studies showed a burden of deleterious variants in epilepsy genes, suggesting a role for oligogenic inheritance.
Sarah Duerinckx, Barbara Gravel, Julie Soblet, Benjamin Legros, Susana Ferrao Santos, Wim Van Paesschen, Estelle Rikir, Epi25 Collaborative, Siwei Chen, Zaid Afawi, Quratulain Zulfiqar Ali, Danielle M. Andrade, Mutluay Arslan, Simona Balestrini, Carmen Barba, Tobias Baumgartner, Betül Baykan, Nerses Bebek, Felicitas Becker, Caitlin A. Bennett, Ahmad Beydoun, Francesca Bisulli, Christian Bosselmann, S. Hande Caglayan, Laura Canafoglia, Barbara Castellotti, Francine Chassoux, I‐Jun Chou, Seo‐Kyung Chung, Patrick Cossette, Chantal Depondt, Orrin Devinsky, Dennis J. Dlugos, Viola Doccini, Colin A. Ellis, Thomas N. Ferraro, Lorenzo Ferri, Mark Fitzgerald, Francesco Fortunato, Elena Freri, Tania Giangregorio, Tracy A. Glauser, Aslı Gundogdu‐Eken, Namrata Gupta, Kevin Haas, Erin L. Heinzen, Christian Hengsbach, Olivia Hoeper, Michele Iacomino, Yushi Inoue, Lara Jehi, Symon M. Kariuki, Karl Martin Klein, Susanne Knake, Andreas Koupparis, Ioanna Kousiappa, Roland Krause, Martin Krenn, Heinz Krestel, Wolfram S. Kunz, Austin Lacey, Stephan Lauxmann, Stephanie L. Leech, Gaetan Lesca, David Lewis‐Smith, Calwing Liao, Laura Licchetta, Kuang‐Lin Lin, Tarja Linnankivi, Daniel H. Lowenstein, Colin H.T. Lui, Ida Manna, Paula Marques, Patrick May, Davide Mei, RaAaella Minardi, Barbara Mostacci, Lorenzo Muccioli, Bernd A. Neubauer, Terence J. O'Brien, Savvas S. Papacostas, Elena Parrini, Manuela Pendziwiat, Francesca Ragona, Mark I. Rees, Antonella Riva, Philippe Ryvlin, Andrea Salmon, Ilaria Sammarra, Marcello Scala, Ingrid E. ScheAer, Susanne Schubert‐Bast, Paolo Scudieri, Graeme J. Sills, Sanjay M. Sisodiya, Hannah Stamberger, Ulrich Stephani, Carlotta Stipa, Pasquale Striano, Adam Strzelczyk, Rainer Surges, Toshimitsu Suzuki, Mariagrazia Talarico, George A. Tanteles, Marian Todaro, Meng‐Han Tsai, Birute Tumiene, Dilsad Turkdogan, Luc Valton, Andreas van Baalen, Annalisa Vetro, Yvonne G. Weber, Sarah Weckhuysen, Peter Widdess‐Walsh, Samuel Wiebe, Randi von Wrede, Kazuhiro Yamakawa, Zuhal Yapıcı, Fritz Zimprich, Milena Zizovic, Gábor Zsurka, Benjamin M. Neale, Samuel F. Berkovic, Solve‐RD DITF‐EpiCARE, Marc Abramowicz, Nicholas Allen, Simona Balestrini, Tobias Bartolomaeus, Ravishankara Bellampalli, Katherine Benson, Francesca Bisulli, Christian Boßelmann, Susan Byrne, Laura Canafoglia, Evelina Carapancea, Barbara Castellotti, Gianpiero Cavalleri, Roberta Cilio, Norman Delanty, Christel Depienne, Chantal Depondt, Sarah Duerinckx, Zakaria Eddafir, Kornelia Ellwanger, Silvana Franceschetti, Elena Freri, Hamidah Ghani, Tiziana Granata, Marie Greally, Renzo Guerrini, Tobias B. Haack, Eva Hammar Bouveret, Michele Iacomino, Rami Jamra, Josua Kegele, Christian Korff, Roland Krause, Alma Küchler, Robert Lauerer‐Braun, Damien Lederer, Elsa Leitão, Holger Lerche, Gaëtan Lesca, David Lewis‐Smith, Laura Licchetta, Frédéric Masclaux, Patrick May, Davide Mei, Cyril Mignot, Charissa Millevert, Raffaella Minardi, Patrick Moloney, Hiltrud Muhle, Mary O. Reghan, Joohyun Park, Elena Parrini, Manuela Pendziwiat, Konrad Platzner, Johanna Pohl, Mary Sandrine, Marcello Scala, Sanjay Sisodiya, Noor Smal, Hannah Stamberger, Pasquale Striano, Roxane van Heurck, Christina Vosseler‐Wolf, David Webb, Sarah Weckhuysen, Federico Zara, Alec Aeby, Guillaume Smits, Chantal Depondt   +192 more
wiley   +1 more source

Effects of vagal nerve stimulation parameters on heart rate variability in epilepsy patients

Frontiers in Neurology
IntroductionVagal nerve stimulation (VNS) is used as an alternative treatment in drug-resistant epilepsy patients. Effects of VNS on the cardiac autonomic system are controversial.
Ahmet Genç, Firdevs Ezgi Uçan Tokuç, Meltem Korucuk   +2 more
doaj   +1 more source

Differential effects of vagus nerve stimulation paradigms guide clinical development for Parkinson’s disease

Brain Stimulation, 2020
Background: Vagus nerve stimulation (VNS) modifies brain rhythms in the locus coeruleus (LC) via the solitary nucleus. Degeneration of the LC in Parkinson’s disease (PD) is an early catalyst of the spreading neurodegenerative process, suggesting that ...
Ariana Q. Farrand, Ryan S. Verner, Ryan M. McGuire, Kristi L. Helke, Vanessa K. Hinson, Heather A. Boger   +5 more
doaj   +1 more source

Bi-level VNS therapy with different therapy modes at night and daytime improves seizures and quality of life in a patient with drug-resistant epilepsy

Epilepsy & Behavior Reports, 2023
Induction or aggravation of sleep apnea is a known side effect of vagus nerve stimulation (VNS). We report the case of a 44 year old male with drug-resistant epilepsy and depression who did not experience any seizure reduction after 1 year of VNS but a ...
Berthold R. Voges
doaj   +1 more source

Effects of VNS on HRV using Poincaré analysis.

, 2018
Representative Poincaré plots of (A) P-VNS and (B) S-VNS (10%) during VNS stimulation (ON) at 10 Hz and 30 Hz demonstrating the elliptical fitting of the beat-distribution cloud and the standard deviation of short-term (SD1) and long-term (SD2 ...
Elizabeth M. Annoni (5029715), Bruce H. KenKnight (5029721), Elena G. Tolkacheva (3942389), Imad Libbus (5029718), Kanchan Kulkarni (5029712), Steven W. Lee (5029724)   +5 more
core   +1 more source

Low‐intensity focused ultrasound neuromodulation for drug‐resistant epilepsy: A randomized, sham‐controlled crossover trial

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to evaluate the safety, feasibility, and efficacy of low‐intensity focused ultrasound (LIFU) as a noninvasive neuromodulation technique in patients with drug‐resistant epilepsy (DRE). Methods In this pilot, single‐blind, randomized sham‐controlled crossover trial, 12 patients with DRE underwent both LIFU and
Chien‐Chen Chou, Yen‐Cheng Shih, Yi‐Hsiu Chen, Po‐Tso Lin, Chun‐Fu Lin, Po‐Chun Chu, Hao‐Li Liu, Cheng‐Chia Lee, Hsiang‐Yu Yu   +8 more
wiley   +1 more source