Results 51 to 60 of about 5,762,967 (332)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Rheology and early microstructure evolution of fresh ultra-high performance concrete with polycarboxylate superplasticizer

open access: yesCase Studies in Construction Materials, 2022
Polycarboxylate superplasticizer (PCE) is a key ingredient in the preparation of ultra-high performance concrete (UHPC). However, it is still unclear how PCE affects hydration and microstructure evolution of UHPC, and how it changes the rheological ...
Chong Zhang   +4 more
doaj   +1 more source

All-aromatic biphenylene end-capped polyquinoline and polyimide matrix resins [PDF]

open access: yes, 1985
Biphenylene end-capped polyquinoline and polyimide resins afford low void content graphite-reinforced composites with good initial properties. However, with both resins, rapid degradation occurs during oxidative isothermal aging at elevated temperatures.
Alston, W. B.   +2 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Drainage Performance of Long Longitudinal Slope and High Safety Permeable Asphalt Pavement

open access: yesBuildings, 2023
Permeable asphalt pavement refers to an asphalt mixture layer with an air void content of more than 18% and internal water permeability and drainage capabilities that can quickly drain away water on the road surface, improve rainy day travel safety, and ...
Haocheng Liu   +6 more
doaj   +1 more source

Effect of sand gradation and fines type on the liquefaction behaviour of sand-fines mixtures [PDF]

open access: yes, 1996
Equivalent granular void ratio and equivalent granular steady state line was used as the common basis for synthesizing test results. In isolating the influence of host sand, two sand-fines mixes with different host sand, but the same fines type and ...
Rahman, M.M., Lo, S.R.
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Laser-induced microexplosion confined in a bulk of silica: formation of nanovoids [PDF]

open access: yes, 2016
We report on the nanovoid formation inside synthetic silica, viosil, by single femtosecond pulses of 30–100nJ energy, 800nm wavelength, and 180fs duration.
Gamaly, Eugene G   +4 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

High Temperature VARTM of Phenylethynyl Terminated Imides [PDF]

open access: yes, 2009
LaRC phenylethynyl terminated imide (PETI) resins were processed into composites using high temperature vacuum assisted resin transfer molding (VARTM). Although initial runs yielded composites with high void content, process modifications reduced voids ...
Britton, Sean M.   +7 more
core   +3 more sources

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