Results 51 to 60 of about 339,821 (318)

Tensor anisotropy as a tracer of cosmic voids

, 2015
We present a new method to find voids in cosmological simulations based on the tidal and the velocity shear tensors definitions of the cosmic web. We use the fractional anisotropy (FA) computed from the eigenvalues of each web scheme as a void tracer. We
Bustamante, Sebastian, Forero-Romero, Jaime E.   +1 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Lensing Measurements of the Mass Distribution in SDSS Voids

, 2015
We measure weak lensing mass profiles of voids from a volume-limited sample of SDSS Luminous Red Galaxies (LRGs). We find voids using an algorithm designed to maximize the lensing signal by dividing the survey volume into 2D slices, and then finding ...
Clampitt, Joseph, Jain, Bhuvnesh
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

The Hierarchical Structure and Dynamics of Voids

, 2012
Contrary to the common view voids have very complex internal structure and dynamics. Here we show how the hierarchy of structures in the density field inside voids is reflected by a similar hierarchy of structures in the velocity field.
A. S. Szalay, Aaronson, Aragon-Calvo, Aragon-Calvo, Aragón-Calvo, Bardeen, Beacom, Bernardeau, Bertschinger, Bertschinger, Biswas, Blumenthal, Bond, Bond, Ceccarelli, Chongchitnan, Colberg, Colberg, Colberg, Colless, Dekel, Doroshkevich, Dressler, Dubinski, Einasto, Einasto, Einasto, Einasto, Einasto, Fillmore, Florack, Furlanetto, Gauch, Geller, Gottlöber, Hausman, Hoffman, Icke, Joeveer, Karachentsev, Kereš, Kirshner, Klypin, Klypin, Klypin, Kofman, Kreckel, Kreckel, Kreckel, Lacey, Lavaux, Lee, Little, Lynden-Bell, M. A. Aragon-Calvo, Mathis, Melott, Melott, Melott, Moore, Nasonova, Neyrinck, Padilla, Paranjape, Park, Patiri, Peebles, Peimbert, Platen, Platen, Romano-Diaz, Romano-Díaz, Sahni, Sato, Schaap, Schaap, Shandarin, Shaya, Sheth, Sheth, Slezak, Sousbie, Springel, Springel, Stanonik, Suhhonenko, Suto, Szomoru, Szomoru, Szomoru, Tarenghi, Tifft, Tully, Tully, van de Weygaert, van de Weygaert, van de Weygaert, van de Weygaert, van de Weygaert, Weistrop, Weistrop, Wong, Zel'dovich, Zeldovich   +103 more
core   +1 more source

Tracing the gravitational potential using cosmic voids [PDF]

, 2017
The properties of large underdensities in the distribution of galaxies in the Universe, known as cosmic voids, are potentially sensitive probes of fundamental physics.
Crittenden, Robert, Hotchkiss, Shaun, Nadathur, Seshadri   +2 more
core   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Cosmic voids in coupled dark energy cosmologies: the impact of halo bias

, 2015
In this work we analyse the properties of cosmic voids in standard and coupled dark energy cosmologies. Using large numerical simulations, we investigate the effects produced by the dark energy coupling on three statistics: the filling factor, the size ...
Baldi, Marco, Marulli, Federico, Moscardini, Lauro, Pollina, Giorgia   +3 more
core   +1 more source

The Size and Shape of Local Voids [PDF]

, 2001
We study the size and shape of low density regions in the local universe which we identify in the smoothed density field of the PSCz flux limited IRAS galaxy catalogue.
Basilakos, Blaes, Branchini, Branchini, Carter, Cole, Coles, Einasto, Eke, El-Ad, El-Ad, El-Ad, Haynes, Hoyle, Jeveer, Kaiser, Kauffmann, Kauffmann, Kirshner, Manolis Plionis, Melott, Melott, Mller, Peebles, Plionis, Plionis, Regs, Rood, Rowan-Robinson, Ryden, Sahni, Saunders, Saunders, Spyros Basilakos, Stavrev, Van de Weygaert, White, Yahil, Zeldovich   +38 more
core   +4 more sources