Results 61 to 70 of about 125,224 (248)

Strengthening of hollow core precast prestressed reinforced concrete slabs using different techniques

Cogent Engineering
Hollow-core precast prestressed reinforced concrete (HCPPRC) slabs have been widely available since the 1980s in different structures due to many advantages.
Abd Elmegeed Abd Elhameed, Eslam Ali, Ragab Mahmoud, Ahmed Eisa, Mohamed H. El-Feky, Peter Sabol, Dušan Katunský   +6 more
doaj   +1 more source

Geomechanical analysis of the impact of the new tunnels construction in the vicinity of existing underground subway structures on the state of the soil massif

Записки Горного института, 2023
The specificity of the behavior of the soil massif near the tunnel under construction in difficult mining conditions is considered. It was revealed through the joint interpretation of the results of geophysical measurements in the tunnel and computer ...
Vladimir V. Nabatov, Aleksandr S. Voznesenskii   +1 more
doaj  

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Responsibility voids [PDF]

, 2010
We present evidence for the existence of 'responsibility voids' in committee decision-making, that is, the existence of situations where no member of a committee can individually be held morally responsible for the outcome.
Van Hees, Martin, Braham, Matthew, Matthew Braham, van Hees, M.V.B.P.M, Martin VanHees   +4 more
core   +1 more source

Numerical simulation of self-piercing riveting process (SRP) using continuum damage mechanics modelling

Fracture and Structural Integrity, 2018
The extended Bonora damage model was used to investigate joinability of materials in self-piercing riveting process. This updated model formulation accounts for void nucleation and growth process and shear-controlled damage which is critical for shear ...
Nicola Bonora, Gabriel Testa, Gianluca Iannitti, Andrew Ruggiero, Domenico Gentile   +4 more
doaj  

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

A Laboratory Investigation into the Effects of the Aggregated Related Facts of Critical VMA in Asphalt Paving Mixtures: TR-415, June 2000 [PDF]

, 2000
This report summarizes research conducted at Iowa State University on behalf of the Iowa Department of Transportation, focusing on the volumetric state of hot-mix asphalt (HMA) mixtures as they transition from stable to unstable configurations.

core  

Responsibility voids and cooperation [PDF]

, 2018
Do responsibility voids exist? That is, are there situations in which the group is collectively morally responsible for some outcome although no member can be held individually morally responsible for it?
Duijf, H.W.A., Hein Duijf
core   +2 more sources

Experimental investigation of the influence of internal defects (voids, wrinkles) on the shear properties of CFRP

Fracture and Structural Integrity
The study focuses on examining the impact of internal manufacturing defects (voids and wrinkles) on the mechanical behavior of structural carbon fiber reinforced polymers (CFRP) under shear loading.
Stanislav Slovikov, Dmitriy Lobanov
doaj   +3 more sources