Results 141 to 150 of about 24,266 (288)

Mechanisms underlying neonate-specific metabolic effects of volatile anesthetics

open access: gold, 2021
Julia Stokes   +13 more
openalex   +1 more source

Associations of Intraoperative Hypotension and Vasopressor Administration With Postoperative Acute Kidney Injury in Children Undergoing Liver Transplantation: A Retrospective Cohort Study

open access: yesPediatric Anesthesia, EarlyView.
ABSTRACT Background Both intraoperative hypotension (IOH) and vasopressor administration are independently associated with postoperative acute kidney injury (AKI) in adults undergoing major noncardiac surgery. Whether these associations extend to children undergoing major noncardiac surgery, such as liver transplantation, remains unknown.
Theodora Wingert   +7 more
wiley   +1 more source

Volatile Anesthetic Sevoflurane Precursor 1,1,1,3,3,3-Hexafluoro-2-Propanol (HFIP) Exerts an Anti-Prion Activity in Prion-Infected Culture Cells. [PDF]

open access: yesNeurochem Res, 2021
Shimizu T   +9 more
europepmc   +1 more source

Effects of General Anesthetics on Excitatory and Inhibitory Synaptic Transmission in Area CA1 of the Rat Hippocamptls In Vitro [PDF]

open access: yes, 1999
It is unclear whether general anesthetics induce enhancement of neural inhibition and/or attenuation of neural excitation.We studied the effects of pentobarbital (5xl0^mol/L), propofol (5x10^ mol/L), ketamine (10^ mol/L), halothane (1.5 vol%) and ...
Wakasugi Masahiro
core   +1 more source

Cardiac‐specific Kv1.1 deficiency alters cardiomyocyte electrophysiology without modifying overall cardiac function or arrhythmia susceptibility

open access: yesExperimental Physiology, EarlyView.
Abstract The leading cause of epilepsy‐related mortality is sudden unexpected death in epilepsy (SUDEP), resulting from seizure‐induced cardiorespiratory arrest by mechanisms that remain unresolved. Mutations in ion channel genes expressed in both brain and heart represent SUDEP risk factors because they can disrupt neural and cardiac rhythms ...
Kelsey Halvorson   +11 more
wiley   +1 more source

Sex‐specific differences in mortality and neurocardiac interactions in the Kv1.1 knockout mouse model of sudden unexpected death in epilepsy (SUDEP)

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The Kcna1 knockout mouse model of sudden unexpected death in epilepsy (SUDEP) exhibits sex‐specific differences in SUDEP risk. Female mice exhibit a lower SUDEP risk than males, despite similar seizure characteristics and interictal cardiac function across sexes.
Kelsey Paulhus   +11 more
wiley   +1 more source

Volatile Anesthetic Sevoflurane Attenuates Toll-Like Receptor 1/2 Activation. [PDF]

open access: yesAnesth Analg, 2020
Mitsui Y   +5 more
europepmc   +1 more source

Synergistic roles of aquaporin 5 and intra‐ and extracellular carbonic anhydrases in promoting CO2 diffusion across the Xenopus oocyte plasma membrane

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Fick's law: JCO2=PM*,CO2±hAQP5·([CO2]os±bCA−[CO2]is±hCAII)TransmembraneCO2gradient${J}_{{\mathrm{CO}}_{2}}=\underset{\pm \mathrm{hAQP}5}{\underset{}{{P}_{\mathrm{M}^\ast ,{\mathrm{CO}}_{2}}}}\, \cdot \underset{\mathrm{Transmembrane}\ {\mathrm{CO}}_{2}\ \mathrm{gradient}}{\underset{}{(\underset{\pm \mathrm{bCA}}{\underset ...
Deng‐Ke Wang   +2 more
wiley   +1 more source

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