Results 141 to 150 of about 681,564 (359)

Propofol inhibits the voltage-gated sodium channel NaChBac at multiple sites. [PDF]

open access: yes, 2018
Voltage-gated sodium (NaV) channels are important targets of general anesthetics, including the intravenous anesthetic propofol. Electrophysiology studies on the prokaryotic NaV channel NaChBac have demonstrated that propofol promotes channel activation ...
Bondarenko, Vasyl   +12 more
core   +1 more source

Paired Assessment of Volatile Anesthetic Concentrations with Synaptic Actions Recorded In Vitro

open access: yesPLoS ONE, 2008
The volatile anesthetic isoflurane poses a number of experimental challenges in the laboratory. Due to its rapid evaporation, the open conditions of most in vitro electrophysiological recording systems make the determination of actual isoflurane ...
S. McDougall   +5 more
semanticscholar   +1 more source

Practical Applications of Secondary/Extractive Electrospray Ionization (SESI): A Versatile Tool for Real‐Time Chemical Analysis

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT In the 1980s, researchers discovered the remarkable ability of electrospray plumes to effectively ionize gas‐phase molecules via secondary ionization. Around 20 years later—coinciding with the ambient mass spectrometry revolution—secondary electrospray ionization (SESI) and extractive electrospray ionization (EESI) coupled to mass spectrometry
Xin Luo   +5 more
wiley   +1 more source

Measuring the Anesthetic Response to Chloroform and Isoflurane in General Anesthesia Mutants in Drosophila melanogaster

open access: yesAnesthesia Research
Objectives: Comparative analyses of anesthetic agents on mutants with altered anesthetic sensitivity remain limited in the current literature. This study examines the sensitivity of various Drosophila melanogaster wild-type strains and mutants to the ...
Ekin Daplan   +2 more
doaj   +1 more source

Are local anesthesia vials similar to champagne: Do they lose their potency once opened?: An in vitro study

open access: yesContemporary Clinical Dentistry, 2017
Background and Objectives: Epinephrine is volatile and unstable on exposure to air. Addition of sodium metabisulfite as an antioxidant has been effective, but there are no clear-cut consensus on its efficiency in retarding the oxidation that sets in once
P S Gopinath Thilak   +3 more
doaj   +1 more source

Anesthetic and analgesic management of a skunk (Mephitis mephitis) undergoing a laminectomy for cauda equina compression [PDF]

open access: yes, 2010
A 6-year-old, male striped skunk (Mephitis mephitis) weighing 5.9 kg was anesthetized for diagnostic imaging procedures and subsequently for a laminectomy at level L6/S1 as treatment of lumbosacral stenosis. On both occasions, anesthesia was induced by a
Gozalo Marcilla, Miguel   +5 more
core  

Efficient analysis of toxicity and mechanisms of isoflurane on postoperative delirium by network toxicology and molecular docking

open access: yesNeuroprotection, EarlyView.
Abstract Postoperative delirium (POD), a prevalent neurological complication in older surgical patients, adversely affects recovery. Isoflurane, a common inhalational anesthetic, exhibits neurotoxic potential, but its role in POD pathogenesis remains unclear.
Zhiming Dai   +3 more
wiley   +1 more source

Semiochemical applications for managing the grey field slug (Deroceras reticulatum Müller), a major pest of arable crops

open access: yesPest Management Science, EarlyView.
Trends in semiochemical research highlight promising attractants and repellents for ‘push–pull’ pest control strategies of the grey field slug. Extracts from plants, predators, entomopathogenic fungi, and essential oils demonstrate potential in modifying grey field slug behaviour, inducing avoidance, antifeeding responses, or mortality, offering ...
Suleiman Mustapha   +5 more
wiley   +1 more source

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