Results 91 to 100 of about 10,634 (223)
Artemia salina Toxicity Assay: Standardization in a 24‐Well Microplate
ABSTRACT Bioassays with Artemia sp. are widely used in aquatic, environmental, and human toxicology as an initial tool to investigate the toxicity of plant extracts, isolated compounds, drugs, and products of natural or synthetic origin. These assays allow for the estimation of the median lethal concentration (LC50) and guide subsequent studies in ...
Matheus Pires Miranda +4 more
wiley +1 more source
Volatile anesthetics in cardiac surgery: the impalpable benefit
Nowadays, there are numerous studies demonstrating that volatile anesthetics reduce mortality and morbidity with a cardio-protective effect. The mechanisms involved in protecting perioperative cardiac ischemic damage provided by desflurane and ...
Candela, Chiara +4 more
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Volatile anesthetics inhibit voltage-dependent Ca2+ channels in porcine tracheal smooth muscle cells
The relaxation of airway smooth muscle by volatile anesthetics is associated with a decreased concentration of intracellular free Ca2+. We hypothesized that inhibition of the entry of extracellular Ca2+ contributes to the relaxation.
M. Yamakage +2 more
core +1 more source
Effects of surgery and anesthetic choice on immunosuppression and cancer recurrence
Background The relationship between surgery and anesthetic-induced immunosuppression and cancer recurrence remains unresolved. Surgery and anesthesia stimulate the hypothalamic–pituitary–adrenal (HPA) axis and sympathetic nervous system (SNS) to cause ...
Ryungsa Kim
doaj +1 more source
Abstract Background Volatile anaesthetic agents contribute to climate change, and reducing this impact is a commendable ambition. We evaluated the efficiency of a veterinary capture device for isoflurane (VET‐can/VET‐dock, SageTech Veterinary) in anaesthetised cats and dogs.
Florence Hillen, David Yates, Kate White
wiley +1 more source
MortalitY in caRdIAc surgery (MYRIAD): A randomizeD controlled trial of volatile anesthetics. Rationale and design [PDF]
Objective There is initial evidence that the use of volatile anesthetics can reduce the postoperative release of cardiac troponin I, the need for inotropic support, and the number of patients requiring prolonged hospitalization following coronary artery ...
Gemma, Marco +167 more
core +1 more source
Cervical cancer is a common malignancy among women, and tumor excision is the most common surgical intervention. Anesthetics used during surgery include general intravenous, volatile, local anesthetics, sedative and analgesic. Studies have shown that the
Linyan Deng +14 more
doaj +1 more source
The Agents of Climate Justice in Healthcare
ABSTRACT This paper addresses the critical issue of decarbonising healthcare systems to help combat climate change. I focus on identifying the ‘agents of justice’ responsible for this transformation. Beginning with the claim that healthcare's greenhouse gas emissions cause injustice, the paper assumes that achieving a net zero healthcare system is ...
Joshua Parker
wiley +1 more source
Methaemoglobinaemia: From pathophysiology to contemporary clinical management
Summary Methaemoglobin (MetHb) is an oxidised form of haemoglobin (Hb) unable to bind oxygen. Raised levels of MetHb reduce the blood's oxygen‐carrying capacity, causing potentially severe hypoxaemia and possible death. The condition arises from three main pathologies: mutations in globin genes causing Haemoglobin‐M, inherited deficiency of the enzyme ...
Alexander J. Twine, David C. Rees
wiley +1 more source
Background: Volatile anesthetics protect against cardiac ischemia-reperfusion injury via adenosine triphosphate-dependent potassium channel activation.
M.S Ayuko Ota-Setlik +4 more
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