Results 91 to 100 of about 10,634 (223)

Artemia salina Toxicity Assay: Standardization in a 24‐Well Microplate

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Bioassays with Artemia sp. are widely used in aquatic, environmental, and human toxicology as an initial tool to investigate the toxicity of plant extracts, isolated compounds, drugs, and products of natural or synthetic origin. These assays allow for the estimation of the median lethal concentration (LC50) and guide subsequent studies in ...
Matheus Pires Miranda   +4 more
wiley   +1 more source

Volatile anesthetics in cardiac surgery: the impalpable benefit

open access: yes, 2018
Nowadays, there are numerous studies demonstrating that volatile anesthetics reduce mortality and morbidity with a cardio-protective effect. The mechanisms involved in protecting perioperative cardiac ischemic damage provided by desflurane and ...
Candela, Chiara   +4 more
core  

Volatile anesthetics inhibit voltage-dependent Ca2+ channels in porcine tracheal smooth muscle cells

open access: yes, 1995
The relaxation of airway smooth muscle by volatile anesthetics is associated with a decreased concentration of intracellular free Ca2+. We hypothesized that inhibition of the entry of extracellular Ca2+ contributes to the relaxation.
M. Yamakage   +2 more
core   +1 more source

Effects of surgery and anesthetic choice on immunosuppression and cancer recurrence

open access: yesJournal of Translational Medicine, 2018
Background The relationship between surgery and anesthetic-induced immunosuppression and cancer recurrence remains unresolved. Surgery and anesthesia stimulate the hypothalamic–pituitary–adrenal (HPA) axis and sympathetic nervous system (SNS) to cause ...
Ryungsa Kim
doaj   +1 more source

Capture of isoflurane from anaesthetised dogs and cats following methadone, medetomidine and ketamine administration

open access: yesVeterinary Record, EarlyView.
Abstract Background Volatile anaesthetic agents contribute to climate change, and reducing this impact is a commendable ambition. We evaluated the efficiency of a veterinary capture device for isoflurane (VET‐can/VET‐dock, SageTech Veterinary) in anaesthetised cats and dogs.
Florence Hillen, David Yates, Kate White
wiley   +1 more source

MortalitY in caRdIAc surgery (MYRIAD): A randomizeD controlled trial of volatile anesthetics. Rationale and design [PDF]

open access: yes, 2017
Objective There is initial evidence that the use of volatile anesthetics can reduce the postoperative release of cardiac troponin I, the need for inotropic support, and the number of patients requiring prolonged hospitalization following coronary artery ...
Gemma, Marco   +167 more
core   +1 more source

Effects of perioperative anesthetics on the postoperative prognosis of patients undergoing surgery for cervical cancer

open access: yesFrontiers in Pharmacology
Cervical cancer is a common malignancy among women, and tumor excision is the most common surgical intervention. Anesthetics used during surgery include general intravenous, volatile, local anesthetics, sedative and analgesic. Studies have shown that the
Linyan Deng   +14 more
doaj   +1 more source

The Agents of Climate Justice in Healthcare

open access: yesBioethics, EarlyView.
ABSTRACT This paper addresses the critical issue of decarbonising healthcare systems to help combat climate change. I focus on identifying the ‘agents of justice’ responsible for this transformation. Beginning with the claim that healthcare's greenhouse gas emissions cause injustice, the paper assumes that achieving a net zero healthcare system is ...
Joshua Parker
wiley   +1 more source

Methaemoglobinaemia: From pathophysiology to contemporary clinical management

open access: yesBritish Journal of Haematology, EarlyView.
Summary Methaemoglobin (MetHb) is an oxidised form of haemoglobin (Hb) unable to bind oxygen. Raised levels of MetHb reduce the blood's oxygen‐carrying capacity, causing potentially severe hypoxaemia and possible death. The condition arises from three main pathologies: mutations in globin genes causing Haemoglobin‐M, inherited deficiency of the enzyme ...
Alexander J. Twine, David C. Rees
wiley   +1 more source

Differential protective effects of volatile anesthetics against renal ischemia-reperfusion injury in vivo

open access: yes, 2004
Background: Volatile anesthetics protect against cardiac ischemia-reperfusion injury via adenosine triphosphate-dependent potassium channel activation.
M.S Ayuko Ota-Setlik   +4 more
core  

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