Results 171 to 180 of about 10,634 (223)

Cardioprotection with Volatile Anesthetics in Cardiac Surgery

Asian Cardiovascular and Thoracic Annals, 2008
Myocardial ischemia during the perioperative period is a major cause of morbidity and mortality after surgery. Experimental data indicate that clinical concentrations of volatile anesthetics protect the myocardium from ischemia and reperfusion injury, as shown by decreased infarct size and more rapid postoperative recovery of contractile function ...
Lorsomradee, Suraphong, Cromheecke, Stefanie, Lorsomradee, Sratwadee, de Hert, Stefan G.   +3 more
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Anesthetic action of volatile anesthetics by using Paramecium as a model

Journal of Huazhong University of Science and Technology [Medical Sciences], 2012
Although empirically well understood in their clinical administration, volatile anesthetics are not yet well comprehended in their mechanism studies. A major conundrum emerging from these studies is that there is no validated model to assess the presumed candidate sites of the anesthetics.
Younian Xu, Shihai Zhang
exaly   +3 more sources

Volatile Anesthetics and Cardiac Function

Seminars in Cardiothoracic and Vascular Anesthesia, 2006
All volatile anesthetics have been shown to induce a dose-dependent decrease in myocardial contractility and cardiac loading conditions. These depressant effects decrease myocardial oxygen demand and may, therefore, have a beneficial role on the myocardial oxygen balance during myocardial ischemia.
de Hert, Stefan G.
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Drug Interactions: Volatile Anesthetics and Opioids

Journal of Clinical Anesthesia, 1997
Multiple drugs are used to provide anesthesia. Volatile anesthetics are commonly combined with opioids. Several studies have demonstrated that small doses of opioid (i.e., within the analgesic range) result in a marked reduction in minimum alveolar concentration (MAC) of the volatile anesthetic that will prevent purposeful movement in 50% of patients ...
P S Glass, T J Gan, B Ginsberg
exaly   +3 more sources

Volatile Anesthetics Reduce Mortality in Cardiac Surgery

Journal of Cardiothoracic and Vascular Anesthesia, 2009
Objectives: A recent meta-analysis suggested that volatile anesthetics reduce postoperative mortality after cardiac surgery. Nonetheless, whether volatile anesthetics improve the outcome of cardiac surgical patients is still a matter of debate.
Giuseppe Biondi-Zoccai, Giovanni Landoni, Imad Sheiban   +2 more
exaly   +3 more sources

Cardioprotection by volatile anesthetics

Vascular Pharmacology, 2005
Preconditioning describes a very powerful endogenous mechanism by which the heart may be protected against ischemia and reperfusion injury. Transient administration of a volatile anesthetic before a prolonged ischemic episode reduces myocardial infarct size to a degree comparable to that observed during ischemic preconditioning.
Martin W, Bienengraeber, Dorothee, Weihrauch, Judy R, Kersten, Paul S, Pagel, David C, Warltier   +4 more
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Mutagenicity of Volatile Anesthetics

Anesthesiology, 1976
The mutagenicity of halothane was tested in an in-vitro microbial assay system employing two histidine-dependent mutants of Salmonella typhimurium, TA98 and TA100, Halothane in concentrations ranging from 0.1 to 30 per cent was incubated with bacteria in the presence or absence of a metabolic activation system prepared from either rat liver treated ...
J M, Baden, M, Brinkenhoff, R S, Wharton, B A, Hitt, V F, Simmon, R I, Mazze   +5 more
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Preconditioning of the Myocardium by Volatile Anesthetics

Current Medicinal Chemistry-Cardiovascular & Hematological Agents, 2004
Cardiovascular disease continues to be a major health problem. Tremendous efforts have been invested in clinical and laboratory research in the hopes of decreasing the risk of patients with cardiovascular disease undergoing cardiac and non-cardiac surgeries.
Wai-Meng, Kwok, Kei, Aizawa
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Volatile anesthetic-induced preconditioning

Perfusion, 2013
The myocardium has an innate ability to protect itself from ischemic events. This protection occurs when the myocardium is exposed to a brief ischemic period prior to a more extreme ischemic event. This is termed ischemic preconditioning.
T, Swyers, D, Redford, D F, Larson
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[Volatile anesthetics].

Der Anaesthesist, 2004
None of the currently available inhaled anesthetics has all of the properties of an "ideal" inhaled agent. The exceptionally low solubility of desflurane and sevoflurane offers a significantly greater precision of control over maintenance of anesthesia and a potential for a more rapid recovery from anesthesia than other inhaled anesthetics. Sevoflurane
M, Loscar, P, Conzen
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