Results 111 to 120 of about 1,098,953 (338)

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

Advanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu, Hongjie Dai, Xiaocui Zhong, Qibin Li, Hui Yuan, Yang Yang, Daiyong Huang, Lei Zhang, Rui Ran, Tian He, Yuanzhi Huang, Silas Villas‐Boas, Sergey Tumanov, Richard D. Cannon, Boris Novakovic, Richard Saffery, Yuhao Zhang, Xiaojing Dong, Ting‐Li Han   +18 more
wiley   +1 more source

Sex‐Specific Regulation of Glycemic Homeostasis by Theabrownin from Pu‐erh Tea

Advanced Science, EarlyView.
Pu‐erh tea's key component, theabrownin (TB), lowers blood glucose in a sex‐specific manner. In females, estrogen boosts intestinal MUC2 production, which dramatically enhances TB's ability to inhibit the carbohydrate‐digesting enzyme α‐glucosidase.
Yang Li, Junliang Kuang, Dan Zheng, Jieyi Wang, Kun Ge, Chun Qu, Xiaojiao Zheng, Zhenxing Ren, Fengjie Huang, Mingliang Zhao, Yimin Sun, Huiheng Zhang, Keke Ding, Xixi Xia, Yajun Tang, Lu Liu, Jian Zhou, Fei Gao, Xiaohui Ma, Yongquan Xu, Guoxiang Xie, Aihua Zhao, Wei Jia   +22 more
wiley   +1 more source

The influence of probabilistic volcanic hazard map properties on hazard communication

Journal of Applied Volcanology, 2015
Probabilistic volcanic hazard analysis is becoming an increasingly popular component of volcanic risk reduction strategies worldwide. While probabilistic hazard analyses offer many advantages for decision-making, displaying the statistical results of ...
M. Thompson, J. Lindsay, J. Gaillard
semanticscholar   +1 more source

Volcanic hazard mapping in Indonesia

, 1999
Indonesia is a wide archipelago where 129 active volcanoes are located. It means that about 13% of active volcanoes all over the world are located in the Indonesian archipelago. The volcanoes are located along the 7,000 km tectonic belt through Sumatera,
Editor Geological Society of Malaysia
core  

Multi-volcanic Hazard Impact Assessment for Residential Buildings in the Auckland Volcanic Field, New Zealand [PDF]

, 2019
Volcanic eruptions can produce many hazards which can impact society yet many cities, including Auckland, are built on or near active volcanoes. Auckland rests on the Auckland Volcanic Field (AVF), an active volcanic field of 500km2, including 53 ...
Allen, Nicole, Stewart, Carol, Wilson, Thomas, Scott, Allan, Kennedy, Ben   +4 more
core  

Re-assessing volcanic hazard maps for improving volcanic risk communication: application to Stromboli active volcanic island (Italy)

, 2010
Hazard and risk maps are tools for both mitigating against risk and informing and preparing the general public. Recent studies have highlighted that volcanic hazard and risk maps used during emergencies can be difficult to interpret. Our research focuses
Isaia, R., Barclay, Jenni, Nave, R., Nave, Rosella, Vilardo, Giuseppe, Giuseppe Vilardo, Rosella Nave, Jenny Barclay, Vilardo, G., Barclay, J., Barclay, Jenny, Roberto Isaia, Isaia, Roberto   +12 more
core   +1 more source

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

Advanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang, Yan Wang, Yi Qin, Luohai Chen, Xiaowu Xu, Guixiong Fan, Desheng Jing, Miaoyan Wei, Xianjun Yu, Junfeng Xu, Shunrong Ji, Jie Chen   +11 more
wiley   +1 more source

Volcanic Hazard Assessments for Nuclear Installations: Methods and Examples in Site Evaluation

, 2016
Volcanic hazards assessments for critical facilities, such as nuclear power plants, often must consider the potential effects from phenomena that have very low likelihoods of occurrence.
W. Aspinall, S. Charbonnier, C. Connor, L. Connor, A. Costa, L. Courtland, H. D. Granados, A. R. Godoy, K. Hibino, B. Hill, J. Komorowski, S. McNutt   +11 more
semanticscholar   +1 more source

PREFACE SPECIAL ISSUE: NEW ANALYTICAL TECHNIQUES FOR UNDERSTANDING VOLCANIC SYSTEMS, FROM MAGMA GENERATION TO THE EMPLACEMENT OF VOLCANIC PRODUCTS

, 2018
The development of new bi- and tri-dimensional (2D, 3D) analytical techniques of volcanic materials representsa new frontier in the world of modern volcanology. These advances not only offer important andreliable information on, e.g., magma vesiculation,
Dioguardi, Fabio, Mele, Daniela, de\u27 Michieli Vitturi, Mattia, de' Michieli Vitturi, Mattia   +3 more
core   +1 more source

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

Advanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang, Cancan Yao, Yan Chen, Ke Cai, Zhouping Lu, Boxuan Wu, Kun Yu, Yan Shi, Jianyuan Zhao, Xiangyu Zhou   +9 more
wiley   +1 more source