Results 31 to 40 of about 26,348 (308)

Flash Assembloids: A Rapid Biofabrication of a Platform for Modeling Early Glioblastoma Invasion at the Glioblastoma–Brain Organoid Interfaces

Advanced Healthcare Materials, EarlyView.
This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang, Henry Robert Howard, Shihui Chen, Won‐Young Choi, Summer Cao, Arthur Chien, Kevin Zou, Michael Kassiou, Fabien Delerue, Ho Sang Jung, Yeonju Park, Young Mee Jung, Yong‐Dae Kwon, Karrie M. Kiang, Gilberto Ka‐Kit Leung, Ryohichi Sugimura, Ann‐Na Cho, Sang Jin Lee   +17 more
wiley   +1 more source

Evaluation of Support Types of Volcanic Clastic Sand and Gravels Based on Electrical Imaging Logging

Cejing jishu, 2023
The combined effect of river transport and volcanic action during the deposition of volcanic clastic sand conglomerate causes large variations in rock grain size and complex pore structure of different grain size combinations, which affects the reservoir
ZHAO Xiaoqing, WANG Xiangyu, ZHANG Zhiguo, ZHANG Weifeng, CHEN Haifeng   +4 more
doaj   +1 more source

Perivascular Matrix Densification Dysregulates Angiogenesis and Activates Pro‐Inflammatory Endothelial Cells

Advanced Science, EarlyView.
Perivascular matrix densification promotes the emergence of aberrant endothelial tip cells (ATECs) that invade and persist within fibrotic microenvironments. Using in vivo lineage tracing and a human microvessel model, this study shows that fibrous matrix cues destabilize VE‐cadherin–mediated junctions to gate TGF‐β signaling, inducing a pro ...
Jingyi Xia, William Y. Wang, Kyle A. Jacobs, Kairav Maniar, Daphne Lin, Evan H. Jarman, Daniel L. Matera, Kristen Loesel, Christopher D. Davidson, Harrison L. Hiraki, Xiaotian Tan, Eve H. Shikanov, Robert N. Kent, Carole Parent, Xudong Fan, Ariella Shikanov, Matthew L. Kutys, Brendon M. Baker   +17 more
wiley   +1 more source

Geotechnical properties of volcanic materials of the Mount Erciyes

, 2010
3rd International Workshop on Rock Mechanics and Geo-Engineering in Volcanic Environments -- MAY 31-JUN 03, 2010 -- Puerto de la Cruz, SPAINThe Mount Erciyes (3917 m) is the largest volcanic mountain of Central Anatolia (Turkey) and situated 15 km south ...
Yuksek, S., Demirci, A.
core   +2 more sources

Unraveling the Molecular Mechanisms Underlying Spontaneous Multipolar Mitosis Through CIN‐seq

Advanced Science, EarlyView.
Multipolar mitosis, a hallmark of chromosomal instability (CIN), drives tumor heterogeneity but is challenging to study in live cells. Using CIN‐seq, a single‐cell multiomics method, we profiled rare CIN events and identified mechanisms associated with viable multipolar mitosis, including PTEN attenuation, Rho GTPase‐driven cytokinesis failure, and ...
Pin‐Rui Su, Ting‐Chun Chou, Maria Teresa López‐Cascales, Junfeng Huang, Tsai‐Ying Chen, Sjoukje van Wieren, Chan Li, Cecile Beerens, Li You, Jelle Storteboom, Miao‐Ping Chien   +10 more
wiley   +1 more source

Comparison of geochemical characteristics and forming environment of volcanic rocks in Northern Xinjiang and the Songliao Basin, China

Journal of Natural Gas Geoscience, 2017
The tectonic settings of Northern Xinjiang, Songliao Basin, and its peripheral areas all belong to the Paleoasian orogenic region. Their main structures are all composed of multiple continental segments and peripheral fold belts. Similar tectonic setting
Yanzhao Wei, Xia Zhao, Shan Lu, Zhongying Zhao   +3 more
doaj   +1 more source

Rhyolitic Ash Promoting Organic Matter Enrichment in a Shallow Carbonate Platform: A Case Study of the Maokou Formation in Eastern Sichuan Basin

Frontiers in Earth Science, 2022
Volcanic ash improves the amount of nutritive elements in the lake and ocean, but it is not fully understood how volcanic ash influences the total organic matter content (TOC) and bio-precursor, and the scope.
Qingqiang Meng, Qingqiang Meng, Qingqiang Meng, Qian Pang, Guang Hu, Zhijun Jin, Zhijun Jin, Zhijun Jin, Donhya Zhu, Donhya Zhu, Jiayi Liu, Jiayi Liu, Chuanwen Zhang   +12 more
doaj   +1 more source

The Microbial Habitability of Weathered Volcanic Glass Inferred from Continuous Sensing Techniques [PDF]

, 2011
Basaltic glasses (hyaloclastite) are a widespread habitat for life in volcanic environments, yet their interior physical conditions are poorly characterized.
Bagshaw, Elizabeth A., Wadham, Jemma L., Venugopalan, T., Matt Mowlem, Cockell, C. S., Jemma L. Wadham, Bagshaw, Elizabeth, Magan, N., Tong Sun, Elizabeth A. Bagshaw, Croxford, Anthony J., Mowlem, M., Cockell, Charles S., Bagshaw, EA, Charles S. Cockell, Naresh Magan, Wadham, JL, T. Venugopalan, Anthony J. Croxford, Sun, Tong, Mowlem, Matt, Sun, T., Magan, Naresh, Croxford, AJ   +23 more
core   +1 more source

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

Advanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang, Yan Wang, Yi Qin, Luohai Chen, Xiaowu Xu, Guixiong Fan, Desheng Jing, Miaoyan Wei, Xianjun Yu, Junfeng Xu, Shunrong Ji, Jie Chen   +11 more
wiley   +1 more source

Cigarette Smoke‐Induced Alveolar Macrophage Senescence via GEM/SIRT3‐Mediated Mitochondrial Dysfunction

Advanced Science, EarlyView.
Cigarette smoke accelerates the aging of immune cells in the lung. By combining human single‐cell sequencing, cell culture, and mouse models, the authors show that the protein GEM drives mitochondrial damage and senescence in alveolar macrophages by suppressing SIRT3.
Jin Wang, Meidan Wei, Xiangrong Song, Jiaxin Zhang, Lisha Zhang, Sixian Chen, Yaoyu Hu, Hui Gao, Jianxiang Li   +8 more
wiley   +1 more source