Results 51 to 60 of about 26,348 (308)

G6PC Downregulation Promotes Renal Calcium Oxalate Stone Formation via Lactate‐Induced SNAIL1 K206 Lactylation and Epithelial‐Mesenchymal Transition

Advanced Science, EarlyView.
In renal calcium oxalate stone formation, G6PC downregulation leads to lactate accumulation. This lactate mediates CBP/p300‐dependent lactylation of SNAIL1 at K206, promoting its nuclear translocation. Nuclear SNAIL1 activates the TGF‐β/SMAD3 pathway, driving epithelial‐mesenchymal transition and fibrosis, which ultimately facilitates crystal ...
Kai Liu, Boming Zhang, Ruixin Fan, Chen Duan, Yangjun Zhang, Huahui Wu, Xiangyang Yao, Xiongmin Mao, Bo Li, Youmiao Zeng, Zhenzhen Xu, Yang Wang, Mengcheng Luo, Xinyu Xu, Ninghan Feng, Heng Li, Hua Xu   +16 more
wiley   +1 more source

Fine description and geologic modeling for volcanic gas reservoirs

Petroleum Exploration and Development, 2010
To understand the geology of volcanic gas reservoir development, research was carried out on volcanic rock, body lithology, lithofacies, fractures, gas and water zones, reservoir classification, and geologic modeling for volcanic gas reservoirs.
Song Xinmin, Ran Qiquan, Sun Yuanhui, Wang Yongjun, Yan Lin, Chen Fuli   +5 more
doaj   +1 more source

From Dome to Disease: The Respiratory Toxicity of Volcanic Cristobalite [PDF]

, 2012
Exposure to fine-grained volcanic ash can potentially cause acute and chronic respiratory disease. The toxicity of ash is likely to vary depending on the type and style of eruption; eruptions at dome-forming volcanoes, in particular, can produce ash ...
DAMBY, DAVID,ERNEST
core  

Detailed studies and stabilization methods of volcanic rocky slopes in coastal areas, Canary Islands, Spain

, 2010
Natural relief on mountainous volcanic islands has deep ravines, steep rocky slopes and high coastal cliffs. Volcanic formations have very heterogeneous rocks and soils. Besides, civil and building works sometimes include high cuts on the terrain and, as
R García-Ferrera, Lomoschitz, A., García-Ferrera, R., A Lomoschitz, A Cilleros, Cilleros, A.   +5 more
core   +1 more source

The RNA‐Binding Protein PARN Remodeled 3′ UTR Structure Defines Poly(A)‐Loading Sites to Mediate Immunoglobulin Homeostasis

Advanced Science, EarlyView.
ABSTRACT Class Switch Recombination (CSR) is essential for generating high‐affinity antibody isotypes from IgM during adaptive humoral responses. Despite well‐established roles for various transcription factors, whether CSR is subject to dedicated post‐transcriptional control represents a significant gap in knowledge.
Siyuan Sun, Chen Yang, Xiaoyu Wang, Naijing Hu, Shengyao Zhang, Xinchun Li, Yu Chen, Jianan Zhai, Xiangfeng Tang, Wei Lu, Chenxu Lu, Changchang Cao, Weiru Yu, Wenhao Wu, Xiaonan Nie, Fengchao Wang, Bing Fang, Fazheng Ren, Yixuan Li, Juan Chen   +19 more
wiley   +1 more source

Activity Enhancement Study of Xinjiang Silica-Alumina Volcanic Rock Powder through Different Activation Processes

Applied Sciences
In response to the dilemma of the scarcity of mineral additions and the high cost of long-distance transport in Hotan, Xinjiang, China, this paper presented an activation process study on the feasibility of volcanic rock powders unique to this region as ...
Shuhong Yang, Yingjie Wu, Huaiyi Wang, Guiquan Yang, Xiangyi Ding, Zhaoxuan Xia   +5 more
doaj   +1 more source

Discrimination of hot versus cold avalanche deposits: Implications for hazard assessment at Mount Meager, B.C. [PDF]

Natural Hazards and Earth System Sciences, 2003
The surficial deposits surrounding the Mount Meager volcanic complex include numerous avalanche deposits. These deposits share many attributes: (a) they are nearly monolithologic and comprise mainly intermediate volcanic rock clasts, (b) they lack ...
M. L. Stewart, J. K. Russell, C. J. Hickson   +2 more
doaj  

Volcanic and sedimentary processes in phreatomagmatic volcanoes [PDF]

, 1982
Phreatomagmatic volcanoes form when ascending magma explosively interacts with surface or groundwater at shallow depths. Three types of phreatomagmatic activity are recognised- phreaticp phreatomagmatic (s. s. ) and surtseyan - based on the degree of
Leys, C.A., Leys, Clyde Andrew
core  

Mitochondrial Carrier SLC25A13 Drives Ferroptosis Resistance and Immune Evasion via a STAT3–IFI6 Circuit in Breast Cancer

Advanced Science, EarlyView.
SLC25A13 is identified as an immunometabolic driver of triple‐negative breast cancer that sustains ferroptosis resistance and immune evasion through a STAT3–IFI6 circuit. Pharmacologic degradation of SLC25A13 restores ferroptosis sensitivity and enhances anti‐PD‐1 efficacy, highlighting a strategy to convert immune‐cold tumors into immunotherapy ...
Yingze Zhu, Yuhan Tang, Yingcui Chen, Zhuoqi Zhang, Yige Lu, Xinyue Wang, Qiyuan Shi, Wenhui Zhao, Hui Pang   +8 more
wiley   +1 more source

Diagenetic Evolution of Syngenetic Volcanogenic Sediment and Their Influence on Sandstone Reservoir: A Case Study in the Southern Huizhou Sag, Pearl River Mouth Basin, Northern South China Sea

Journal of Marine Science and Engineering
The Paleogene sandstone reservoir of Huizhou Sag is an important target for deep exploration in the Pearl River Mouth Basin, South China Sea. Because of the intense volcanic activity, it had a significant impact on the development of reservoirs, making ...
Jiahao Chen, Hongtao Zhu, Guangrong Peng, Lin Ding, Zhiwei Zeng, Wei Wang, Wenfang Tao, Fengjuan Zhou   +7 more
doaj   +1 more source