Results 41 to 50 of about 38,057 (315)

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

Advanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang, Yan Wang, Yi Qin, Luohai Chen, Xiaowu Xu, Guixiong Fan, Desheng Jing, Miaoyan Wei, Xianjun Yu, Junfeng Xu, Shunrong Ji, Jie Chen   +11 more
wiley   +1 more source

Fracture mechanics of volcanic eruptions [PDF]

, 2009
Seismology is a key tool in the forecasting of volcanic eruptions. The onset of an eruption is often preceded and accompanied by an increase in local seismic activity, driven by fracturing within the edifice.
Matthews, C., Matthews, C
core  

Sr-Nd isotope geochemistry of the early Precambrian sub-alkaline mafic igneous rocks from the southern Bastar craton, Central India [PDF]

, 2009
Sr–Nd isotope data are reported for the early Precambrian sub-alkaline mafic igneous rocks of the southern Bastar craton, central India. These mafic rocks are mostly dykes but there are a few volcanic exposures.
Ellam, R.M., Ellam, Rob M., Gautam, Gulab C., Srivastava, R.K., Gautam, G.C., Srivastava, Rajesh K.   +5 more
core   +1 more source

Cigarette Smoke‐Induced Alveolar Macrophage Senescence via GEM/SIRT3‐Mediated Mitochondrial Dysfunction

Advanced Science, EarlyView.
Cigarette smoke accelerates the aging of immune cells in the lung. By combining human single‐cell sequencing, cell culture, and mouse models, the authors show that the protein GEM drives mitochondrial damage and senescence in alveolar macrophages by suppressing SIRT3.
Jin Wang, Meidan Wei, Xiangrong Song, Jiaxin Zhang, Lisha Zhang, Sixian Chen, Yaoyu Hu, Hui Gao, Jianxiang Li   +8 more
wiley   +1 more source

Exploration breakthrough and hydrocarbon accumulation conditions of Mesozoic volcanic rocks in Bodong Low Uplift, Bohai Bay Basin, China

Petroleum Exploration and Development
The Mesozoic volcanic rocks of the Bodong Low Uplift in the Bohai Bay Basin have been studied and explored for years. In 2024, the LK7-A well drilled in this region tested high-yield oil and gas flows from volcanic weathered crust.
Changgui XU, Haifeng YANG, Lei CHEN, Yanfei GAO, Shaofeng BU, Qi LI   +5 more
doaj   +1 more source

The Archaean to Proterozoic igneous rocks of the Pilbara region, Western Australia –internationally significant geology of a globally unique potential geopark

International Journal of Geoheritage and Parks, 2019
The Pilbara region of Western Australia, covering some 500 km × 500 km, provides a diversity of Archaean to Proterozoic igneous rocks in a relatively compact area that records a younging southward crustal history of igneous activity, sedimentation, early
V. Semeniuk, M. Brocx
doaj   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Volcanic rocks in the 21st century: Multifaceted applications for sustainable development

Green Technologies and Sustainability
Volcanic rocks, with their diverse physicochemical properties, are pivotal in numerous scientific and industrial applications. This review comprehensively examines the multifaceted uses of volcanic rocks, focusing on their roles in sustainable ...
Hang Yang, Hongli Diao, Shibin Xia
doaj   +1 more source

Geochemistry and tectonic setting of volcanic rocks in the Mahiroud volcano-plutonic complex, Southeast of Sarbisheh (Eastern Iran) [PDF]

پترولوژی
Introduction Mahiroud volcano-plutonic complex as an anticline (Lahnu-Mahiroud) forms a part of the Sistan suture zone (SiSuZ), and lies in the northern part of the Sistan suture zone (SiSuZ). According to Tirrul et al.
Sahar Benrashidiyan, Ahmad Ahmadi Khalaji, Peyman Eskandarnia, Shahriar Keshtgar, Zahra Tahmasbi   +4 more
doaj   +1 more source

PORE STRUCTURES AND RESERVOIR CHARACTERISTICS OF VOLCANIC ROCKS IN THE CARBONIFEROUS BATAMAYINEISHAN FORMATION IN THE SHUANGJINGZI AREA, EASTERN JUNGGAR BASIN (WESTERN CHINA)

Rudarsko-geološko-naftni Zbornik, 2021
Junggar Basin is one of the largest sedimentary basins in Northwest China. Carboniferous oil and gas fields have been found in different areas in the eastern part of the Junggar Basin on a large scale, indicating that the Carboniferous rocks of the ...
Masab Ali, Bian Weihua, Yang Kaikai, Muhammad Sabeh Khan Panni   +3 more
doaj   +1 more source